Mutagenetix > Incidental Mutation

Incidental Mutation 'R0415:Eml6'

40257

Institutional Source

Beutler Lab

Gene Symbol

Eml6

Ensembl Gene

ENSMUSG00000044072

Gene Name

echinoderm microtubule associated protein like 6

Synonyms

MMRRC Submission

038617-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.223) question?

Stock #

R0415 (G1)

Quality Score

208

Status

Validated

Chromosome

Chromosomal Location

29743048-30026033 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 29749392 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 1787 (V1787A)

Ref Sequence

ENSEMBL: ENSMUSP00000051080 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058902] [ENSMUST00000137689]

AlphaFold

Q5SQM0

Predicted Effect

possibly damaging
Transcript: ENSMUST00000058902
AA Change: V1787A

PolyPhen 2 Score 0.836 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000051080
Gene: ENSMUSG00000044072
AA Change: V1787A

Domain	Start	End	E-Value	Type
low complexity region	36	47	N/A	INTRINSIC
WD40	49	91	1.79e-1	SMART
WD40	94	136	1.42e-4	SMART
WD40	139	178	5.31e-4	SMART
WD40	184	224	8.84e1	SMART
WD40	225	263	3.75e-4	SMART
WD40	313	353	4.69e-5	SMART
WD40	356	394	2.22e0	SMART
WD40	397	436	1.72e0	SMART
WD40	505	546	1.7e2	SMART
WD40	552	592	4.55e-3	SMART
low complexity region	613	625	N/A	INTRINSIC
Pfam:HELP	653	715	1.9e-22	PFAM
WD40	716	757	9.24e-1	SMART
WD40	760	802	6.53e-4	SMART
WD40	805	844	2.98e-1	SMART
WD40	856	891	8.52e1	SMART
WD40	892	929	2.09e-2	SMART
WD40	986	1026	1.18e-1	SMART
WD40	1032	1068	3.44e0	SMART
WD40	1071	1111	2.58e-1	SMART
WD40	1180	1221	9.24e-1	SMART
WD40	1227	1267	3.85e-1	SMART
low complexity region	1280	1291	N/A	INTRINSIC
Pfam:HELP	1329	1402	5e-15	PFAM
WD40	1404	1447	2.66e0	SMART
WD40	1450	1492	1.85e0	SMART
WD40	1495	1534	2.97e0	SMART
WD40	1543	1582	7.1e1	SMART
WD40	1584	1629	9.51e1	SMART
WD40	1675	1715	3.05e-4	SMART
WD40	1718	1758	8.84e1	SMART
WD40	1759	1798	7.16e-1	SMART
WD40	1869	1910	1.53e1	SMART
WD40	1916	1956	4.62e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123881

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000137017

Predicted Effect

probably benign
Transcript: ENSMUST00000137689

SMART Domains

Protein: ENSMUSP00000116197
Gene: ENSMUSG00000044072

Domain	Start	End	E-Value	Type
SCOP:d2bbkh_	14	72	9e-8	SMART
Blast:WD40	22	64	1e-24	BLAST

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000142651

Meta Mutation Damage Score

0.0844

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.7%
20x: 93.6%

Validation Efficiency

97% (99/102)

Allele List at MGI

Other mutations in this stock

Total: 98 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933427G23Rik	A	T	5: 23,831,050 (GRCm38)		noncoding transcript	Het
Acox2	A	G	14: 8,243,835 (GRCm38)		probably benign	Het
Adgb	T	C	10: 10,431,067 (GRCm38)		probably null	Het
Adgra3	C	A	5: 49,961,757 (GRCm38)		probably benign	Het
Adgre4	G	A	17: 55,852,288 (GRCm38)	V658I	probably benign	Het
Ahnak	A	G	19: 9,012,871 (GRCm38)		probably benign	Het
Anapc2	A	G	2: 25,278,325 (GRCm38)	T159A	probably damaging	Het
Arfgef3	A	G	10: 18,613,127 (GRCm38)		probably benign	Het
Atf7ip	C	T	6: 136,560,012 (GRCm38)	S81L	possibly damaging	Het
Cacna1i	A	G	15: 80,368,830 (GRCm38)		probably benign	Het
Camk1	A	T	6: 113,341,891 (GRCm38)	Y20*	probably null	Het
Ccdc40	T	C	11: 119,232,118 (GRCm38)	Y249H	possibly damaging	Het
Cd109	T	A	9: 78,712,615 (GRCm38)	S1380T	probably benign	Het
Cfap57	A	T	4: 118,569,431 (GRCm38)	L1107Q	possibly damaging	Het
Col6a4	C	T	9: 106,075,080 (GRCm38)	V540I	probably damaging	Het
Cst9	T	A	2: 148,838,442 (GRCm38)		probably benign	Het
Cul5	C	T	9: 53,667,070 (GRCm38)	V73I	probably benign	Het
Cxcl16	T	A	11: 70,458,748 (GRCm38)	K84*	probably null	Het
Cyp2c29	T	C	19: 39,329,095 (GRCm38)		probably benign	Het
D6Ertd527e	C	G	6: 87,111,524 (GRCm38)	T223S	unknown	Het
Dip2c	C	T	13: 9,568,289 (GRCm38)		probably benign	Het
Dis3	A	T	14: 99,087,456 (GRCm38)	I513N	probably damaging	Het
Dnajc16	A	T	4: 141,789,048 (GRCm38)	L3*	probably null	Het
Dopey1	T	A	9: 86,506,502 (GRCm38)	L480M	probably damaging	Het
Etnk1	A	G	6: 143,180,774 (GRCm38)	N115S	probably damaging	Het
Fryl	T	C	5: 73,098,414 (GRCm38)	Y758C	probably damaging	Het
Gbp4	G	A	5: 105,121,106 (GRCm38)	R394C	possibly damaging	Het
Ggnbp2	A	C	11: 84,833,225 (GRCm38)		probably benign	Het
Gm7137	A	G	10: 77,788,173 (GRCm38)		probably benign	Het
Gstm2	T	A	3: 107,984,006 (GRCm38)	Q132L	probably benign	Het
Habp2	T	C	19: 56,317,717 (GRCm38)		probably benign	Het
Hectd2	T	C	19: 36,584,884 (GRCm38)		probably benign	Het
Htr6	A	G	4: 139,062,081 (GRCm38)	I291T	possibly damaging	Het
Ighg2c	T	C	12: 113,287,910 (GRCm38)	D199G	unknown	Het
Itih2	A	G	2: 10,105,615 (GRCm38)		probably benign	Het
Kcnab2	A	G	4: 152,395,136 (GRCm38)	F248S	probably benign	Het
Kcnc4	T	C	3: 107,445,433 (GRCm38)	K610E	probably damaging	Het
Kcnk16	T	A	14: 20,262,975 (GRCm38)		probably null	Het
Kndc1	C	T	7: 139,930,124 (GRCm38)	T1293I	probably damaging	Het
Lcp1	A	T	14: 75,227,006 (GRCm38)	I556F	possibly damaging	Het
Lrrc8d	T	C	5: 105,811,865 (GRCm38)	L47P	probably damaging	Het
Lyst	T	C	13: 13,711,610 (GRCm38)		probably benign	Het
Macrod2	G	A	2: 142,210,145 (GRCm38)		probably null	Het
Micalcl	C	T	7: 112,381,028 (GRCm38)	R70C	probably damaging	Het
Mllt3	ACTGCTGCTGCTGCTGCTGCT	ACTGCTGCTGCTGCTGCT	4: 87,841,339 (GRCm38)		probably benign	Het
Msh3	A	G	13: 92,346,786 (GRCm38)	V283A	possibly damaging	Het
Nup205	T	C	6: 35,214,634 (GRCm38)		probably benign	Het
Nxpe2	T	C	9: 48,326,614 (GRCm38)	T114A	probably damaging	Het
Olfr1023	A	T	2: 85,887,438 (GRCm38)	I213F	possibly damaging	Het
Olfr1034	A	T	2: 86,047,055 (GRCm38)	H191L	probably benign	Het
Olfr229	A	G	9: 39,909,983 (GRCm38)	Y60C	probably damaging	Het
Olfr78	C	T	7: 102,742,087 (GRCm38)	M305I	probably benign	Het
Olfr893	A	T	9: 38,209,973 (GRCm38)	M305L	probably benign	Het
Pard3	G	A	8: 127,610,566 (GRCm38)	G1221D	probably damaging	Het
Pax5	G	A	4: 44,691,886 (GRCm38)	A120V	probably damaging	Het
Pcsk6	C	T	7: 66,033,874 (GRCm38)	R746C	probably damaging	Het
Pif1	G	A	9: 65,588,051 (GRCm38)	C81Y	probably benign	Het
Plcb1	A	G	2: 135,337,499 (GRCm38)	Y609C	probably damaging	Het
Plcd4	C	A	1: 74,552,097 (GRCm38)	S217Y	probably damaging	Het
Plxna1	G	A	6: 89,357,336 (GRCm38)	H104Y	probably benign	Het
Polr2k	A	G	15: 36,175,456 (GRCm38)	Y45C	probably damaging	Het
Pqlc3	C	A	12: 16,997,710 (GRCm38)		probably benign	Het
Prex1	A	G	2: 166,586,699 (GRCm38)		probably benign	Het
Pth2r	A	G	1: 65,388,439 (GRCm38)	M424V	probably benign	Het
Pygm	A	G	19: 6,391,366 (GRCm38)	R464G	probably benign	Het
Rad51c	A	G	11: 87,397,655 (GRCm38)	L234P	probably damaging	Het
Rnf145	A	G	11: 44,525,138 (GRCm38)	Y60C	probably damaging	Het
Rnf167	T	C	11: 70,649,699 (GRCm38)	I135T	probably damaging	Het
Rnf213	A	T	11: 119,414,469 (GRCm38)	I509F	probably damaging	Het
Ryr2	T	C	13: 11,869,156 (GRCm38)	S213G	probably damaging	Het
Selenbp1	T	C	3: 94,936,913 (GRCm38)	V27A	possibly damaging	Het
Selenof	T	G	3: 144,577,692 (GRCm38)	L14R	probably damaging	Het
Sfswap	A	T	5: 129,504,126 (GRCm38)	D121V	probably damaging	Het
Slc25a34	C	A	4: 141,620,469 (GRCm38)	M300I	possibly damaging	Het
Slc34a3	T	G	2: 25,229,110 (GRCm38)	T583P	probably benign	Het
Smg1	C	A	7: 118,182,468 (GRCm38)	A1199S	probably benign	Het
Spint1	A	G	2: 119,245,615 (GRCm38)	T231A	probably damaging	Het
Sptbn1	A	C	11: 30,149,576 (GRCm38)	N229K	probably damaging	Het
Sult2b1	A	G	7: 45,730,092 (GRCm38)		probably benign	Het
Tas2r123	A	T	6: 132,847,838 (GRCm38)	M233L	probably damaging	Het
Tbcel	C	A	9: 42,444,500 (GRCm38)	C139F	probably benign	Het
Thbs2	A	C	17: 14,679,973 (GRCm38)	S573A	probably benign	Het
Tmem132c	A	G	5: 127,563,705 (GRCm38)	E980G	probably damaging	Het
Tmem247	G	T	17: 86,922,322 (GRCm38)	C197F	probably damaging	Het
Tmem251	T	A	12: 102,744,876 (GRCm38)	Y119*	probably null	Het
Tmem43	C	A	6: 91,482,318 (GRCm38)	P257Q	probably benign	Het
Tmprss13	A	G	9: 45,337,132 (GRCm38)		probably null	Het
Trove2	G	T	1: 143,760,075 (GRCm38)	N444K	probably benign	Het
Ubr5	T	C	15: 37,972,980 (GRCm38)	T2626A	probably damaging	Het
Vmn1r196	T	A	13: 22,293,836 (GRCm38)	V215D	probably damaging	Het
Vmn1r22	G	T	6: 57,900,332 (GRCm38)	T220K	probably benign	Het
Vmn2r116	G	A	17: 23,387,279 (GRCm38)	M388I	possibly damaging	Het
Vmn2r74	A	C	7: 85,961,410 (GRCm38)	C25G	probably damaging	Het
Xndc1	T	C	7: 102,080,616 (GRCm38)		probably benign	Het
Zfp282	A	G	6: 47,897,881 (GRCm38)	D340G	probably damaging	Het
Zfp282	T	A	6: 47,905,053 (GRCm38)	I558N	possibly damaging	Het
Zfp316	T	A	5: 143,264,491 (GRCm38)	T56S	unknown	Het
Zfp345	A	G	2: 150,474,559 (GRCm38)		probably benign	Het

Other mutations in Eml6

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01071:Eml6	APN	11	29,850,816 (GRCm38)	critical splice donor site	probably null
IGL01407:Eml6	APN	11	29,755,021 (GRCm38)	nonsense	probably null
IGL01434:Eml6	APN	11	29,819,090 (GRCm38)	missense	probably damaging	1.00
IGL01578:Eml6	APN	11	29,850,870 (GRCm38)	missense	probably benign	0.02
IGL01780:Eml6	APN	11	29,805,175 (GRCm38)	missense	probably benign	0.17
IGL01821:Eml6	APN	11	29,821,699 (GRCm38)	missense	probably benign	0.00
IGL01837:Eml6	APN	11	29,777,055 (GRCm38)	missense	probably benign	0.00
IGL01904:Eml6	APN	11	29,838,613 (GRCm38)	nonsense	probably null
IGL01972:Eml6	APN	11	29,838,451 (GRCm38)	missense	possibly damaging	0.67
IGL02134:Eml6	APN	11	29,759,066 (GRCm38)	missense	probably benign	0.13
IGL02192:Eml6	APN	11	29,805,743 (GRCm38)	missense	probably benign	0.00
IGL02377:Eml6	APN	11	29,777,282 (GRCm38)	missense	probably damaging	0.98
IGL02584:Eml6	APN	11	29,749,387 (GRCm38)	missense	probably damaging	0.99
IGL02587:Eml6	APN	11	29,784,236 (GRCm38)	missense	possibly damaging	0.92
IGL02810:Eml6	APN	11	29,849,016 (GRCm38)	missense	possibly damaging	0.94
IGL02873:Eml6	APN	11	29,880,700 (GRCm38)	missense	probably benign	0.10
IGL02880:Eml6	APN	11	29,749,959 (GRCm38)	missense	probably benign	0.03
IGL03289:Eml6	APN	11	29,795,328 (GRCm38)	missense	possibly damaging	0.49
IGL03301:Eml6	APN	11	29,764,083 (GRCm38)	missense	probably benign	0.18
IGL03386:Eml6	APN	11	29,749,934 (GRCm38)	missense	probably benign
IGL03407:Eml6	APN	11	29,906,330 (GRCm38)	missense	probably damaging	1.00
PIT4453001:Eml6	UTSW	11	29,802,489 (GRCm38)	missense	probably damaging	1.00
R0125:Eml6	UTSW	11	29,882,088 (GRCm38)	missense	probably benign	0.19
R0240:Eml6	UTSW	11	29,792,367 (GRCm38)	missense	possibly damaging	0.84
R0240:Eml6	UTSW	11	29,792,367 (GRCm38)	missense	possibly damaging	0.84
R0271:Eml6	UTSW	11	29,848,949 (GRCm38)	missense	possibly damaging	0.48
R0304:Eml6	UTSW	11	29,777,441 (GRCm38)	missense	probably benign	0.00
R0449:Eml6	UTSW	11	29,893,213 (GRCm38)	missense	probably benign	0.01
R0538:Eml6	UTSW	11	29,760,010 (GRCm38)	splice site	probably benign
R0671:Eml6	UTSW	11	29,805,065 (GRCm38)	missense	probably benign	0.00
R0766:Eml6	UTSW	11	29,831,219 (GRCm38)	splice site	probably benign
R0800:Eml6	UTSW	11	29,749,877 (GRCm38)	missense	probably benign	0.08
R0841:Eml6	UTSW	11	29,777,430 (GRCm38)	missense	probably benign	0.41
R0879:Eml6	UTSW	11	29,850,816 (GRCm38)	critical splice donor site	probably null
R1061:Eml6	UTSW	11	29,777,267 (GRCm38)	missense	probably damaging	1.00
R1145:Eml6	UTSW	11	29,777,430 (GRCm38)	missense	probably benign	0.41
R1145:Eml6	UTSW	11	29,777,430 (GRCm38)	missense	probably benign	0.41
R1172:Eml6	UTSW	11	29,749,824 (GRCm38)	missense	possibly damaging	0.54
R1173:Eml6	UTSW	11	29,749,824 (GRCm38)	missense	possibly damaging	0.54
R1174:Eml6	UTSW	11	29,749,824 (GRCm38)	missense	possibly damaging	0.54
R1199:Eml6	UTSW	11	29,755,044 (GRCm38)	missense	possibly damaging	0.93
R1311:Eml6	UTSW	11	29,831,088 (GRCm38)	splice site	probably benign
R1312:Eml6	UTSW	11	29,831,219 (GRCm38)	splice site	probably benign
R1355:Eml6	UTSW	11	29,833,085 (GRCm38)	missense	probably benign	0.03
R1370:Eml6	UTSW	11	29,833,085 (GRCm38)	missense	probably benign	0.03
R1457:Eml6	UTSW	11	30,024,459 (GRCm38)	missense	probably damaging	1.00
R1486:Eml6	UTSW	11	29,805,114 (GRCm38)	missense	possibly damaging	0.83
R1511:Eml6	UTSW	11	29,818,374 (GRCm38)	missense	probably damaging	1.00
R1532:Eml6	UTSW	11	29,792,256 (GRCm38)	splice site	probably null
R1642:Eml6	UTSW	11	29,777,001 (GRCm38)	critical splice donor site	probably null
R1682:Eml6	UTSW	11	29,759,065 (GRCm38)	missense	probably benign	0.13
R1687:Eml6	UTSW	11	29,833,187 (GRCm38)	missense	probably damaging	1.00
R1699:Eml6	UTSW	11	29,746,282 (GRCm38)	nonsense	probably null
R1796:Eml6	UTSW	11	29,881,975 (GRCm38)	missense	probably benign	0.19
R1797:Eml6	UTSW	11	29,882,041 (GRCm38)	missense	probably benign	0.09
R1837:Eml6	UTSW	11	29,749,802 (GRCm38)	splice site	probably null
R1874:Eml6	UTSW	11	29,831,136 (GRCm38)	missense	probably damaging	0.99
R1967:Eml6	UTSW	11	30,024,545 (GRCm38)	missense	probably damaging	1.00
R1969:Eml6	UTSW	11	29,833,075 (GRCm38)	missense	probably benign
R2007:Eml6	UTSW	11	29,848,814 (GRCm38)	critical splice donor site	probably null
R2012:Eml6	UTSW	11	29,831,128 (GRCm38)	missense	possibly damaging	0.85
R2198:Eml6	UTSW	11	29,850,935 (GRCm38)	missense	probably benign	0.01
R2217:Eml6	UTSW	11	29,818,907 (GRCm38)	missense	probably damaging	1.00
R2218:Eml6	UTSW	11	29,818,907 (GRCm38)	missense	probably damaging	1.00
R2403:Eml6	UTSW	11	29,802,434 (GRCm38)	missense	probably benign	0.05
R2520:Eml6	UTSW	11	29,791,993 (GRCm38)	missense	probably damaging	1.00
R2937:Eml6	UTSW	11	29,833,049 (GRCm38)	splice site	probably benign
R2938:Eml6	UTSW	11	29,833,049 (GRCm38)	splice site	probably benign
R3085:Eml6	UTSW	11	29,809,332 (GRCm38)	missense	probably damaging	0.96
R3236:Eml6	UTSW	11	29,831,097 (GRCm38)	critical splice donor site	probably null
R3738:Eml6	UTSW	11	29,803,137 (GRCm38)	missense	probably benign	0.20
R3739:Eml6	UTSW	11	29,803,137 (GRCm38)	missense	probably benign	0.20
R3752:Eml6	UTSW	11	29,809,360 (GRCm38)	missense	probably benign	0.06
R3854:Eml6	UTSW	11	29,749,905 (GRCm38)	missense	possibly damaging	0.76
R3941:Eml6	UTSW	11	29,803,167 (GRCm38)	missense	probably damaging	0.98
R4034:Eml6	UTSW	11	29,803,137 (GRCm38)	missense	probably benign	0.20
R4049:Eml6	UTSW	11	29,838,577 (GRCm38)	missense	probably damaging	1.00
R4108:Eml6	UTSW	11	29,805,136 (GRCm38)	missense	probably damaging	0.98
R4657:Eml6	UTSW	11	29,805,108 (GRCm38)	missense	possibly damaging	0.77
R4662:Eml6	UTSW	11	29,777,390 (GRCm38)	missense	probably damaging	1.00
R4665:Eml6	UTSW	11	29,819,007 (GRCm38)	nonsense	probably null
R4721:Eml6	UTSW	11	29,838,525 (GRCm38)	missense	possibly damaging	0.95
R4729:Eml6	UTSW	11	29,833,204 (GRCm38)	missense	probably damaging	1.00
R4766:Eml6	UTSW	11	29,805,757 (GRCm38)	missense	probably benign	0.22
R4810:Eml6	UTSW	11	29,755,011 (GRCm38)	missense	possibly damaging	0.92
R4831:Eml6	UTSW	11	29,777,052 (GRCm38)	nonsense	probably null
R5035:Eml6	UTSW	11	29,854,187 (GRCm38)	missense	probably benign	0.00
R5064:Eml6	UTSW	11	29,749,300 (GRCm38)	missense	probably benign	0.12
R5103:Eml6	UTSW	11	29,850,905 (GRCm38)	missense	possibly damaging	0.65
R5121:Eml6	UTSW	11	29,744,606 (GRCm38)	missense	probably benign	0.03
R5161:Eml6	UTSW	11	30,024,467 (GRCm38)	missense	probably damaging	0.99
R5211:Eml6	UTSW	11	29,854,145 (GRCm38)	missense	probably benign	0.02
R5268:Eml6	UTSW	11	29,803,108 (GRCm38)	missense	probably benign	0.15
R5390:Eml6	UTSW	11	29,760,096 (GRCm38)	missense	probably damaging	1.00
R5529:Eml6	UTSW	11	29,764,126 (GRCm38)	missense	probably benign	0.04
R6239:Eml6	UTSW	11	29,749,275 (GRCm38)	missense	probably damaging	1.00
R6326:Eml6	UTSW	11	29,819,066 (GRCm38)	missense	probably damaging	1.00
R6395:Eml6	UTSW	11	29,809,321 (GRCm38)	missense	probably benign	0.00
R6476:Eml6	UTSW	11	29,791,971 (GRCm38)	critical splice donor site	probably null
R6483:Eml6	UTSW	11	29,749,875 (GRCm38)	missense	probably benign	0.00
R6701:Eml6	UTSW	11	29,785,748 (GRCm38)	missense	probably damaging	0.98
R6753:Eml6	UTSW	11	29,754,987 (GRCm38)	missense	probably damaging	1.00
R6809:Eml6	UTSW	11	29,803,161 (GRCm38)	missense	probably benign	0.23
R6847:Eml6	UTSW	11	29,818,447 (GRCm38)	missense	probably benign	0.00
R6855:Eml6	UTSW	11	29,751,381 (GRCm38)	splice site	probably null
R7168:Eml6	UTSW	11	29,838,529 (GRCm38)	missense	probably benign	0.01
R7175:Eml6	UTSW	11	29,784,231 (GRCm38)	missense	probably benign	0.00
R7305:Eml6	UTSW	11	29,777,258 (GRCm38)	missense	probably benign	0.01
R7615:Eml6	UTSW	11	29,802,501 (GRCm38)	missense	possibly damaging	0.49
R7692:Eml6	UTSW	11	29,753,085 (GRCm38)	missense	probably damaging	0.98
R7980:Eml6	UTSW	11	29,833,205 (GRCm38)	missense	probably damaging	1.00
R8026:Eml6	UTSW	11	29,749,973 (GRCm38)	missense	possibly damaging	0.63
R8046:Eml6	UTSW	11	29,758,981 (GRCm38)	missense	probably damaging	0.99
R8049:Eml6	UTSW	11	29,893,201 (GRCm38)	missense	possibly damaging	0.95
R8114:Eml6	UTSW	11	29,754,910 (GRCm38)	missense	probably damaging	1.00
R8425:Eml6	UTSW	11	29,755,008 (GRCm38)	missense	probably benign	0.00
R8799:Eml6	UTSW	11	29,758,981 (GRCm38)	missense	probably benign	0.11
R8945:Eml6	UTSW	11	29,753,110 (GRCm38)	missense	probably damaging	0.98
R8977:Eml6	UTSW	11	29,784,182 (GRCm38)	missense	possibly damaging	0.59
R8986:Eml6	UTSW	11	29,805,181 (GRCm38)	missense	possibly damaging	0.92
R9088:Eml6	UTSW	11	29,818,424 (GRCm38)	missense	probably damaging	0.96
R9150:Eml6	UTSW	11	29,805,791 (GRCm38)	missense	probably benign	0.15
R9209:Eml6	UTSW	11	29,831,175 (GRCm38)	missense	probably damaging	1.00
R9288:Eml6	UTSW	11	29,838,641 (GRCm38)	critical splice acceptor site	probably null
R9467:Eml6	UTSW	11	29,819,076 (GRCm38)	missense	probably damaging	0.99
R9481:Eml6	UTSW	11	29,838,641 (GRCm38)	critical splice acceptor site	probably null
R9534:Eml6	UTSW	11	29,784,155 (GRCm38)	missense	possibly damaging	0.45
RF037:Eml6	UTSW	11	29,752,549 (GRCm38)	critical splice acceptor site	probably benign
RF039:Eml6	UTSW	11	29,752,551 (GRCm38)	critical splice acceptor site	probably benign

Predicted Primers

PCR Primer
(F):5'- GGTTGCCCCTGAGACAAGTTAACG -3'
(R):5'- TGCTTCCACAGCAGGCTAATCAAG -3'

Sequencing Primer
(F):5'- CAAGTTAACGAGAAGCATACCTG -3'
(R):5'- CCCACACAGTCTTTTTAGATATGGTG -3'

Posted On

2013-05-23