Incidental Mutation 'R4755:Cd109'
| ID |
404195 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cd109
|
| Ensembl Gene |
ENSMUSG00000046186 |
| Gene Name |
CD109 antigen |
| Synonyms |
Gov platelet alloantigens, 9930012E15Rik |
| MMRRC Submission |
042033-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4755 (G1)
|
| Quality Score |
205 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
78615546-78716253 bp(+) (GRCm38) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
CATTTATTTATTTATTTATTTATTTATTTATTTAT to CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT
at 78712500 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091330
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093812]
|
| AlphaFold |
Q8R422 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093812
|
| SMART Domains |
Protein: ENSMUSP00000091330
Gene: ENSMUSG00000046186
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
129 |
220 |
1.5e-16 |
PFAM |
|
A2M_N_2
|
470 |
601 |
8.89e-32 |
SMART |
|
A2M
|
695 |
786 |
2.07e-32 |
SMART |
|
Pfam:Thiol-ester_cl
|
912 |
941 |
2.6e-20 |
PFAM |
|
Pfam:A2M_comp
|
961 |
1197 |
1.9e-65 |
PFAM |
|
low complexity region
|
1265 |
1275 |
N/A |
INTRINSIC |
|
A2M_recep
|
1311 |
1395 |
2.06e-27 |
SMART |
|
low complexity region
|
1422 |
1437 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
96% (112/117) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
PHENOTYPE: Mice homozygous for a null mutation display epidermal hyperplasia and thickening, sebaceous gland hyperplasia and transient impairment of hair growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930449A18Rik |
T |
A |
3: 59,825,859 (GRCm38) |
|
noncoding transcript |
Het |
| Accs |
T |
C |
2: 93,841,337 (GRCm38) |
E236G |
probably damaging |
Het |
| Agrn |
C |
T |
4: 156,173,522 (GRCm38) |
|
probably benign |
Het |
| Ahi1 |
A |
G |
10: 21,055,047 (GRCm38) |
I929V |
possibly damaging |
Het |
| Akap5 |
C |
A |
12: 76,327,807 (GRCm38) |
C4* |
probably null |
Het |
| Amotl2 |
A |
T |
9: 102,720,480 (GRCm38) |
H146L |
probably damaging |
Het |
| Ank1 |
A |
G |
8: 23,104,974 (GRCm38) |
N666S |
probably damaging |
Het |
| Atp10d |
A |
T |
5: 72,246,166 (GRCm38) |
T373S |
probably benign |
Het |
| Bpifb9b |
T |
A |
2: 154,319,694 (GRCm38) |
M582K |
probably benign |
Het |
| Brca2 |
T |
A |
5: 150,559,987 (GRCm38) |
|
probably null |
Het |
| C130079G13Rik |
C |
T |
3: 59,936,314 (GRCm38) |
A143V |
probably benign |
Het |
| C330021F23Rik |
A |
T |
8: 3,583,922 (GRCm38) |
S8C |
probably damaging |
Het |
| Ccdc149 |
A |
G |
5: 52,404,151 (GRCm38) |
V229A |
probably damaging |
Het |
| Cdk5rap2 |
A |
G |
4: 70,238,425 (GRCm38) |
S1617P |
probably damaging |
Het |
| Cenpk |
A |
T |
13: 104,249,512 (GRCm38) |
H305L |
probably benign |
Het |
| Cenpk |
A |
T |
13: 104,230,871 (GRCm38) |
M37L |
probably benign |
Het |
| Ces5a |
C |
A |
8: 93,535,677 (GRCm38) |
A11S |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,928,361 (GRCm38) |
E186G |
probably damaging |
Het |
| Cfh |
T |
A |
1: 140,088,808 (GRCm38) |
I593F |
probably damaging |
Het |
| Clstn2 |
C |
T |
9: 97,445,673 (GRCm38) |
V961I |
probably benign |
Het |
| Cog5 |
T |
A |
12: 31,869,406 (GRCm38) |
|
probably null |
Het |
| Col4a4 |
T |
C |
1: 82,541,174 (GRCm38) |
D100G |
unknown |
Het |
| Cyp3a41a |
T |
C |
5: 145,715,506 (GRCm38) |
D61G |
probably damaging |
Het |
| Dnah10 |
A |
G |
5: 124,747,745 (GRCm38) |
N655S |
probably benign |
Het |
| Dnaic1 |
C |
G |
4: 41,610,269 (GRCm38) |
T295R |
probably damaging |
Het |
| Dnajc6 |
C |
T |
4: 101,550,799 (GRCm38) |
A44V |
probably damaging |
Het |
| Eif4enif1 |
A |
T |
11: 3,244,016 (GRCm38) |
D960V |
probably damaging |
Het |
| Fam167b |
C |
T |
4: 129,578,342 (GRCm38) |
G12R |
probably damaging |
Het |
| Fam20b |
A |
T |
1: 156,687,496 (GRCm38) |
Y266* |
probably null |
Het |
| Fer1l6 |
T |
A |
15: 58,640,211 (GRCm38) |
V1509D |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,928,483 (GRCm38) |
I105N |
probably damaging |
Het |
| Fmo2 |
T |
C |
1: 162,888,805 (GRCm38) |
D71G |
probably damaging |
Het |
| Folr2 |
T |
C |
7: 101,843,799 (GRCm38) |
T6A |
possibly damaging |
Het |
| Fry |
A |
C |
5: 150,398,254 (GRCm38) |
E1018A |
probably damaging |
Het |
| Gas2l2 |
A |
G |
11: 83,429,367 (GRCm38) |
I21T |
probably damaging |
Het |
| Gfra1 |
T |
C |
19: 58,453,244 (GRCm38) |
Y85C |
probably damaging |
Het |
| Gm9117 |
T |
C |
3: 93,938,786 (GRCm38) |
|
probably null |
Het |
| Gpld1 |
A |
T |
13: 24,979,688 (GRCm38) |
Y43F |
probably benign |
Het |
| Gpld1 |
T |
A |
13: 24,979,692 (GRCm38) |
Y44* |
probably null |
Het |
| Grid2 |
A |
G |
6: 63,908,988 (GRCm38) |
T123A |
probably benign |
Het |
| Grina |
T |
C |
15: 76,249,242 (GRCm38) |
L305P |
probably damaging |
Het |
| Gucy1a1 |
G |
A |
3: 82,094,795 (GRCm38) |
A659V |
probably benign |
Het |
| H2-T10 |
T |
A |
17: 36,118,945 (GRCm38) |
K319* |
probably null |
Het |
| Hey2 |
A |
T |
10: 30,834,304 (GRCm38) |
V151E |
probably benign |
Het |
| Ighv1-69 |
G |
A |
12: 115,623,558 (GRCm38) |
T13I |
probably benign |
Het |
| Il1rap |
C |
A |
16: 26,722,782 (GRCm38) |
A591E |
probably benign |
Het |
| Ildr1 |
T |
C |
16: 36,722,021 (GRCm38) |
L261P |
probably benign |
Het |
| Jak1 |
A |
G |
4: 101,174,157 (GRCm38) |
Y463H |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 41,269,273 (GRCm38) |
I1666V |
probably benign |
Het |
| Lrp1b |
T |
A |
2: 41,471,016 (GRCm38) |
T592S |
probably benign |
Het |
| Lrrc36 |
A |
G |
8: 105,452,144 (GRCm38) |
T445A |
possibly damaging |
Het |
| Ly9 |
G |
A |
1: 171,607,238 (GRCm38) |
S29F |
probably damaging |
Het |
| Mapk7 |
A |
C |
11: 61,490,843 (GRCm38) |
C32W |
probably damaging |
Het |
| March10 |
C |
T |
11: 105,364,476 (GRCm38) |
|
probably benign |
Het |
| Mier2 |
A |
T |
10: 79,549,197 (GRCm38) |
M119K |
probably damaging |
Het |
| Mpv17 |
A |
T |
5: 31,145,982 (GRCm38) |
C59* |
probably null |
Het |
| Mrpl27 |
G |
A |
11: 94,653,833 (GRCm38) |
|
probably benign |
Het |
| Myo18b |
G |
A |
5: 112,874,474 (GRCm38) |
Q351* |
probably null |
Het |
| Myo1a |
A |
G |
10: 127,715,688 (GRCm38) |
I704M |
probably damaging |
Het |
| Nadsyn1 |
A |
G |
7: 143,806,913 (GRCm38) |
C373R |
probably damaging |
Het |
| Nckipsd |
C |
A |
9: 108,814,739 (GRCm38) |
A513E |
probably benign |
Het |
| Neb |
T |
C |
2: 52,220,209 (GRCm38) |
D209G |
probably damaging |
Het |
| Nkapl |
T |
A |
13: 21,468,287 (GRCm38) |
Q52L |
unknown |
Het |
| Nptx2 |
G |
A |
5: 144,546,440 (GRCm38) |
S126N |
probably benign |
Het |
| Olfr13 |
G |
A |
6: 43,174,043 (GRCm38) |
S19N |
probably benign |
Het |
| Olfr653 |
T |
A |
7: 104,580,061 (GRCm38) |
Y138* |
probably null |
Het |
| Olfr829 |
A |
T |
9: 18,857,180 (GRCm38) |
H185L |
probably benign |
Het |
| Olfr917 |
A |
G |
9: 38,665,832 (GRCm38) |
V4A |
probably benign |
Het |
| Pclo |
A |
T |
5: 14,714,348 (GRCm38) |
R4278S |
unknown |
Het |
| Pcnx |
T |
G |
12: 81,950,294 (GRCm38) |
L988R |
probably damaging |
Het |
| Prl2c5 |
C |
A |
13: 13,189,385 (GRCm38) |
N75K |
probably benign |
Het |
| Prpf19 |
T |
G |
19: 10,897,790 (GRCm38) |
|
probably benign |
Het |
| Ralgapa1 |
A |
G |
12: 55,712,748 (GRCm38) |
S997P |
probably damaging |
Het |
| Rangap1 |
T |
C |
15: 81,712,917 (GRCm38) |
T226A |
probably benign |
Het |
| Rimklb |
G |
A |
6: 122,456,406 (GRCm38) |
L262F |
probably damaging |
Het |
| Rnf169 |
A |
G |
7: 99,925,723 (GRCm38) |
M555T |
probably benign |
Het |
| Rp1l1 |
A |
T |
14: 64,030,070 (GRCm38) |
D1035V |
probably benign |
Het |
| Scd2 |
T |
A |
19: 44,301,352 (GRCm38) |
L262Q |
probably damaging |
Het |
| Scgb2b12 |
T |
A |
7: 32,325,531 (GRCm38) |
M84L |
probably benign |
Het |
| Shroom3 |
G |
T |
5: 92,943,086 (GRCm38) |
V1151F |
probably damaging |
Het |
| Sipa1l1 |
G |
A |
12: 82,372,386 (GRCm38) |
V613I |
possibly damaging |
Het |
| Slc25a23 |
T |
A |
17: 57,052,794 (GRCm38) |
D67V |
possibly damaging |
Het |
| Slc25a39 |
C |
T |
11: 102,406,666 (GRCm38) |
|
probably benign |
Het |
| Slc4a10 |
T |
A |
2: 62,296,988 (GRCm38) |
F895Y |
probably damaging |
Het |
| Slc5a4a |
A |
C |
10: 76,186,564 (GRCm38) |
K578Q |
probably benign |
Het |
| Slc6a13 |
G |
A |
6: 121,325,049 (GRCm38) |
G197S |
probably damaging |
Het |
| Smarca2 |
A |
T |
19: 26,654,483 (GRCm38) |
E566V |
possibly damaging |
Het |
| Sorbs3 |
A |
T |
14: 70,184,099 (GRCm38) |
N594K |
probably benign |
Het |
| Spata22 |
A |
T |
11: 73,345,756 (GRCm38) |
D296V |
probably damaging |
Het |
| Sphk2 |
G |
A |
7: 45,713,634 (GRCm38) |
A11V |
possibly damaging |
Het |
| Spp1 |
A |
T |
5: 104,435,215 (GRCm38) |
|
probably benign |
Het |
| Strn3 |
T |
A |
12: 51,610,216 (GRCm38) |
I760L |
possibly damaging |
Het |
| Syk |
A |
T |
13: 52,641,986 (GRCm38) |
Y539F |
probably benign |
Het |
| Thsd7b |
T |
A |
1: 130,210,264 (GRCm38) |
Y1560N |
probably benign |
Het |
| Tmod2 |
C |
A |
9: 75,597,212 (GRCm38) |
E42* |
probably null |
Het |
| Tom1l1 |
T |
C |
11: 90,685,116 (GRCm38) |
E30G |
probably damaging |
Het |
| Trav10 |
G |
A |
14: 53,506,061 (GRCm38) |
A40T |
probably benign |
Het |
| Trav14-2 |
G |
A |
14: 53,640,780 (GRCm38) |
|
probably benign |
Het |
| Tril |
T |
A |
6: 53,818,464 (GRCm38) |
E591V |
probably damaging |
Het |
| Trp53bp1 |
T |
A |
2: 121,228,606 (GRCm38) |
R179* |
probably null |
Het |
| Tspoap1 |
A |
T |
11: 87,771,663 (GRCm38) |
D562V |
possibly damaging |
Het |
| Usp44 |
A |
T |
10: 93,846,906 (GRCm38) |
H406L |
probably damaging |
Het |
| Vangl1 |
A |
G |
3: 102,158,292 (GRCm38) |
I509T |
probably benign |
Het |
| Vax2 |
T |
G |
6: 83,711,397 (GRCm38) |
L34W |
probably damaging |
Het |
| Vmn1r55 |
A |
T |
7: 5,147,026 (GRCm38) |
C133S |
probably damaging |
Het |
| Vmn2r8 |
T |
A |
5: 108,801,700 (GRCm38) |
D427V |
probably benign |
Het |
| Vwde |
A |
G |
6: 13,205,852 (GRCm38) |
I232T |
possibly damaging |
Het |
| Wnk1 |
C |
A |
6: 119,963,470 (GRCm38) |
A769S |
probably damaging |
Het |
| Xpo4 |
A |
C |
14: 57,618,181 (GRCm38) |
S264A |
probably benign |
Het |
| Zfp330 |
A |
T |
8: 82,769,386 (GRCm38) |
C75* |
probably null |
Het |
| Zfp526 |
T |
A |
7: 25,225,639 (GRCm38) |
L441Q |
probably benign |
Het |
| Zfp607b |
T |
G |
7: 27,703,505 (GRCm38) |
L462R |
probably damaging |
Het |
| Zfp719 |
T |
A |
7: 43,590,793 (GRCm38) |
F602I |
probably damaging |
Het |
|
| Other mutations in Cd109 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Cd109
|
APN |
9 |
78,616,969 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00465:Cd109
|
APN |
9 |
78,660,934 (GRCm38) |
nonsense |
probably null |
|
|
IGL00667:Cd109
|
APN |
9 |
78,684,877 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01432:Cd109
|
APN |
9 |
78,698,123 (GRCm38) |
missense |
probably benign |
|
|
IGL01795:Cd109
|
APN |
9 |
78,661,765 (GRCm38) |
splice site |
probably benign |
|
|
IGL02343:Cd109
|
APN |
9 |
78,688,955 (GRCm38) |
splice site |
probably benign |
|
|
IGL02450:Cd109
|
APN |
9 |
78,695,850 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
IGL02699:Cd109
|
APN |
9 |
78,671,989 (GRCm38) |
splice site |
probably benign |
|
|
IGL02738:Cd109
|
APN |
9 |
78,691,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02797:Cd109
|
APN |
9 |
78,661,713 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL03160:Cd109
|
APN |
9 |
78,661,056 (GRCm38) |
splice site |
probably null |
|
|
IGL03349:Cd109
|
APN |
9 |
78,636,485 (GRCm38) |
missense |
probably benign |
0.34 |
|
FR4589:Cd109
|
UTSW |
9 |
78,712,529 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R0048:Cd109
|
UTSW |
9 |
78,680,021 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R0060:Cd109
|
UTSW |
9 |
78,703,107 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0060:Cd109
|
UTSW |
9 |
78,703,107 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0158:Cd109
|
UTSW |
9 |
78,688,932 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R0415:Cd109
|
UTSW |
9 |
78,712,615 (GRCm38) |
missense |
probably benign |
0.13 |
|
R0659:Cd109
|
UTSW |
9 |
78,680,170 (GRCm38) |
splice site |
probably benign |
|
|
R0709:Cd109
|
UTSW |
9 |
78,671,978 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0840:Cd109
|
UTSW |
9 |
78,664,330 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0909:Cd109
|
UTSW |
9 |
78,636,473 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0945:Cd109
|
UTSW |
9 |
78,688,941 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R1344:Cd109
|
UTSW |
9 |
78,672,550 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R1471:Cd109
|
UTSW |
9 |
78,654,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1484:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R1570:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R1688:Cd109
|
UTSW |
9 |
78,705,091 (GRCm38) |
missense |
probably benign |
0.17 |
|
R1773:Cd109
|
UTSW |
9 |
78,703,724 (GRCm38) |
missense |
probably benign |
0.21 |
|
R1813:Cd109
|
UTSW |
9 |
78,617,005 (GRCm38) |
missense |
probably benign |
0.04 |
|
R2004:Cd109
|
UTSW |
9 |
78,703,762 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2083:Cd109
|
UTSW |
9 |
78,667,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2483:Cd109
|
UTSW |
9 |
78,667,357 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2857:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2858:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2859:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2911:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2912:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2914:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R2927:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3623:Cd109
|
UTSW |
9 |
78,667,357 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3713:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3760:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3762:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3771:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3772:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3773:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3916:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R3917:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4117:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4260:Cd109
|
UTSW |
9 |
78,636,463 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R4387:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4389:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4526:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4527:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4528:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4700:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4708:Cd109
|
UTSW |
9 |
78,672,589 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4723:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4750:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4751:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4754:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4773:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R4984:Cd109
|
UTSW |
9 |
78,634,677 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5259:Cd109
|
UTSW |
9 |
78,710,152 (GRCm38) |
missense |
probably benign |
0.30 |
|
R5353:Cd109
|
UTSW |
9 |
78,710,239 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5440:Cd109
|
UTSW |
9 |
78,680,164 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5559:Cd109
|
UTSW |
9 |
78,660,968 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5701:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R5995:Cd109
|
UTSW |
9 |
78,700,279 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5997:Cd109
|
UTSW |
9 |
78,705,062 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6103:Cd109
|
UTSW |
9 |
78,698,314 (GRCm38) |
splice site |
probably null |
|
|
R6174:Cd109
|
UTSW |
9 |
78,665,546 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6410:Cd109
|
UTSW |
9 |
78,657,516 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6529:Cd109
|
UTSW |
9 |
78,712,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6655:Cd109
|
UTSW |
9 |
78,684,938 (GRCm38) |
missense |
probably benign |
0.44 |
|
R6704:Cd109
|
UTSW |
9 |
78,680,075 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6772:Cd109
|
UTSW |
9 |
78,680,810 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R6817:Cd109
|
UTSW |
9 |
78,714,955 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6903:Cd109
|
UTSW |
9 |
78,636,603 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7294:Cd109
|
UTSW |
9 |
78,712,635 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7432:Cd109
|
UTSW |
9 |
78,714,943 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7566:Cd109
|
UTSW |
9 |
78,680,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7767:Cd109
|
UTSW |
9 |
78,710,159 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7986:Cd109
|
UTSW |
9 |
78,688,766 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8017:Cd109
|
UTSW |
9 |
78,707,546 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R8019:Cd109
|
UTSW |
9 |
78,707,546 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R8050:Cd109
|
UTSW |
9 |
78,664,351 (GRCm38) |
missense |
probably benign |
0.28 |
|
R8225:Cd109
|
UTSW |
9 |
78,661,690 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8269:Cd109
|
UTSW |
9 |
78,665,682 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8479:Cd109
|
UTSW |
9 |
78,667,346 (GRCm38) |
nonsense |
probably null |
|
|
R8493:Cd109
|
UTSW |
9 |
78,657,519 (GRCm38) |
missense |
probably benign |
0.41 |
|
R8781:Cd109
|
UTSW |
9 |
78,636,647 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8977:Cd109
|
UTSW |
9 |
78,707,528 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9051:Cd109
|
UTSW |
9 |
78,712,531 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R9051:Cd109
|
UTSW |
9 |
78,712,500 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R9228:Cd109
|
UTSW |
9 |
78,669,760 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R9366:Cd109
|
UTSW |
9 |
78,714,993 (GRCm38) |
missense |
probably benign |
0.11 |
|
R9430:Cd109
|
UTSW |
9 |
78,667,416 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9572:Cd109
|
UTSW |
9 |
78,660,306 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9691:Cd109
|
UTSW |
9 |
78,703,792 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9736:Cd109
|
UTSW |
9 |
78,712,636 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9749:Cd109
|
UTSW |
9 |
78,684,884 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9751:Cd109
|
UTSW |
9 |
78,698,160 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9752:Cd109
|
UTSW |
9 |
78,707,552 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9789:Cd109
|
UTSW |
9 |
78,634,662 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R9797:Cd109
|
UTSW |
9 |
78,671,935 (GRCm38) |
missense |
probably benign |
0.04 |
|
RF002:Cd109
|
UTSW |
9 |
78,712,528 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF002:Cd109
|
UTSW |
9 |
78,712,523 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF003:Cd109
|
UTSW |
9 |
78,712,531 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF011:Cd109
|
UTSW |
9 |
78,712,528 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF013:Cd109
|
UTSW |
9 |
78,712,531 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF047:Cd109
|
UTSW |
9 |
78,712,527 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF060:Cd109
|
UTSW |
9 |
78,712,525 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
Z1177:Cd109
|
UTSW |
9 |
78,691,313 (GRCm38) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTTTAGTAGACGGGGACTAAG -3'
(R):5'- AAAATGCCTGCCTTGATTCCC -3'
Sequencing Primer
(F):5'- GGGGACTAAGAACCATTCCTCTG -3'
(R):5'- GCCTTGATTCCCAAAGTCTTAGAAAC -3'
|
| Posted On |
2016-07-22 |
Incidental Mutation