Incidental Mutation 'R0009:Rims2'
| ID |
40496 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rims2
|
| Ensembl Gene |
ENSMUSG00000037386 |
| Gene Name |
regulating synaptic membrane exocytosis 2 |
| Synonyms |
2810036I15Rik, Syt3-rs, RIM2 |
| MMRRC Submission |
038304-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.518)
|
| Stock # |
R0009 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
39198261-39684372 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 39534966 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 1087
(M1087K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154153
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042917]
[ENSMUST00000082054]
[ENSMUST00000227243]
|
| AlphaFold |
Q9EQZ7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000042917
AA Change: M1109K
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000048719
Gene: ENSMUSG00000037386
AA Change: M1109K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
30 |
154 |
9.5e-18 |
PFAM |
|
low complexity region
|
315 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
498 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
521 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
540 |
N/A |
INTRINSIC |
|
PDZ
|
646 |
725 |
8.27e-16 |
SMART |
|
low complexity region
|
740 |
748 |
N/A |
INTRINSIC |
|
C2
|
790 |
897 |
4.08e-21 |
SMART |
|
low complexity region
|
905 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1130 |
N/A |
INTRINSIC |
|
low complexity region
|
1208 |
1238 |
N/A |
INTRINSIC |
|
C2
|
1432 |
1535 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082054
|
| SMART Domains |
Protein: ENSMUSP00000080711
Gene: ENSMUSG00000037386
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
76 |
194 |
2.2e-11 |
PFAM |
|
low complexity region
|
355 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
538 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
561 |
N/A |
INTRINSIC |
|
low complexity region
|
567 |
580 |
N/A |
INTRINSIC |
|
PDZ
|
686 |
765 |
8.27e-16 |
SMART |
|
low complexity region
|
780 |
788 |
N/A |
INTRINSIC |
|
C2
|
830 |
937 |
4.08e-21 |
SMART |
|
low complexity region
|
945 |
959 |
N/A |
INTRINSIC |
|
low complexity region
|
1075 |
1086 |
N/A |
INTRINSIC |
|
low complexity region
|
1166 |
1196 |
N/A |
INTRINSIC |
|
C2
|
1390 |
1493 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000227243
AA Change: M1087K
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000227381
AA Change: M807K
|
| Meta Mutation Damage Score |
0.2959 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
100% (68/68) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]
PHENOTYPE: Mice homozygous for a knock-out allele show reduced body size, aberrant insulin granule exocytosis, and impaired secretion of hormones associated with glucose homeostasis. Mice homozygous for another knock-out allele show a slightly reduced body size, abnormal maternal behavior and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 66 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A1bg |
T |
G |
15: 60,919,633 (GRCm38) |
|
probably benign |
Het |
| Abcg4 |
T |
G |
9: 44,277,649 (GRCm38) |
|
probably benign |
Het |
| Afm |
C |
A |
5: 90,545,384 (GRCm38) |
|
probably benign |
Het |
| Ahrr |
G |
A |
13: 74,283,024 (GRCm38) |
|
probably benign |
Het |
| Aplnr |
T |
A |
2: 85,137,276 (GRCm38) |
|
probably null |
Het |
| Arih2 |
T |
A |
9: 108,611,727 (GRCm38) |
H264L |
probably damaging |
Het |
| Atp1a1 |
A |
T |
3: 101,579,835 (GRCm38) |
I886N |
possibly damaging |
Het |
| Bmf |
A |
T |
2: 118,549,622 (GRCm38) |
V14E |
probably damaging |
Het |
| Ccdc116 |
T |
C |
16: 17,144,039 (GRCm38) |
E15G |
probably damaging |
Het |
| Ccdc175 |
T |
C |
12: 72,135,965 (GRCm38) |
N427D |
possibly damaging |
Het |
| Cfap53 |
A |
G |
18: 74,299,176 (GRCm38) |
H45R |
probably benign |
Het |
| Chd3 |
A |
G |
11: 69,349,906 (GRCm38) |
L1569P |
probably damaging |
Het |
| Cntn2 |
G |
A |
1: 132,516,180 (GRCm38) |
Q457* |
probably null |
Het |
| Coro1a |
A |
T |
7: 126,701,413 (GRCm38) |
|
probably benign |
Het |
| Cracr2b |
T |
A |
7: 141,463,759 (GRCm38) |
L91Q |
probably damaging |
Het |
| Ctdspl |
T |
C |
9: 119,020,046 (GRCm38) |
|
probably null |
Het |
| Dip2b |
T |
A |
15: 100,169,312 (GRCm38) |
L565Q |
probably damaging |
Het |
| Dip2c |
T |
A |
13: 9,621,903 (GRCm38) |
C1004S |
probably damaging |
Het |
| Dnah11 |
A |
T |
12: 118,045,522 (GRCm38) |
I2135N |
possibly damaging |
Het |
| Dnah14 |
A |
G |
1: 181,769,407 (GRCm38) |
|
probably benign |
Het |
| Dnase1 |
T |
C |
16: 4,038,946 (GRCm38) |
V147A |
probably damaging |
Het |
| Dusp8 |
T |
C |
7: 142,082,054 (GRCm38) |
|
probably benign |
Het |
| Fer1l6 |
T |
C |
15: 58,662,787 (GRCm38) |
Y1828H |
probably damaging |
Het |
| Flvcr1 |
A |
G |
1: 191,008,191 (GRCm38) |
V544A |
probably benign |
Het |
| Fsd1l |
T |
C |
4: 53,687,209 (GRCm38) |
V311A |
probably benign |
Het |
| Glud1 |
G |
A |
14: 34,334,268 (GRCm38) |
G300S |
probably benign |
Het |
| Gm4847 |
C |
T |
1: 166,630,486 (GRCm38) |
V433I |
probably benign |
Het |
| Gstm3 |
T |
G |
3: 107,967,840 (GRCm38) |
Y62S |
probably damaging |
Het |
| Gtse1 |
C |
T |
15: 85,862,435 (GRCm38) |
P151S |
probably benign |
Het |
| Herc2 |
T |
C |
7: 56,207,812 (GRCm38) |
S4048P |
probably benign |
Het |
| Hp1bp3 |
T |
A |
4: 138,221,683 (GRCm38) |
I19K |
probably benign |
Het |
| Htr7 |
C |
A |
19: 36,041,540 (GRCm38) |
|
probably benign |
Het |
| Il1a |
C |
T |
2: 129,309,074 (GRCm38) |
D10N |
probably damaging |
Het |
| Il22ra2 |
A |
T |
10: 19,624,458 (GRCm38) |
N39I |
probably damaging |
Het |
| Kcnn4 |
T |
C |
7: 24,379,255 (GRCm38) |
C267R |
possibly damaging |
Het |
| Larp1 |
A |
G |
11: 58,055,473 (GRCm38) |
K879R |
possibly damaging |
Het |
| Lcn5 |
T |
A |
2: 25,661,405 (GRCm38) |
|
probably benign |
Het |
| Lep |
T |
A |
6: 29,068,972 (GRCm38) |
C7* |
probably null |
Het |
| Magi2 |
A |
T |
5: 20,611,055 (GRCm38) |
Y747F |
probably benign |
Het |
| Mast4 |
T |
C |
13: 102,742,058 (GRCm38) |
T1223A |
probably damaging |
Het |
| Mcc |
C |
T |
18: 44,445,933 (GRCm38) |
E803K |
probably damaging |
Het |
| Mtmr4 |
T |
C |
11: 87,611,508 (GRCm38) |
I796T |
probably benign |
Het |
| Myef2 |
A |
T |
2: 125,108,978 (GRCm38) |
D312E |
probably benign |
Het |
| Myl3 |
A |
C |
9: 110,767,929 (GRCm38) |
D119A |
probably damaging |
Het |
| Myo19 |
T |
A |
11: 84,888,169 (GRCm38) |
|
probably null |
Het |
| Naa15 |
T |
G |
3: 51,470,219 (GRCm38) |
H763Q |
probably damaging |
Het |
| Pde5a |
C |
T |
3: 122,824,902 (GRCm38) |
|
probably benign |
Het |
| Plpp2 |
C |
T |
10: 79,527,244 (GRCm38) |
R184H |
probably benign |
Het |
| Rab19 |
T |
G |
6: 39,389,687 (GRCm38) |
L179V |
probably damaging |
Het |
| Riox2 |
C |
A |
16: 59,489,367 (GRCm38) |
D361E |
probably benign |
Het |
| Sh3rf1 |
T |
A |
8: 61,226,293 (GRCm38) |
V123E |
probably damaging |
Het |
| Slc35e1 |
A |
T |
8: 72,484,709 (GRCm38) |
N318K |
probably damaging |
Het |
| Slc9a2 |
A |
T |
1: 40,763,602 (GRCm38) |
E604V |
probably benign |
Het |
| Srp72 |
T |
C |
5: 76,987,885 (GRCm38) |
S221P |
probably damaging |
Het |
| Tbx19 |
A |
T |
1: 165,160,520 (GRCm38) |
S15T |
possibly damaging |
Het |
| Tcea2 |
A |
G |
2: 181,685,817 (GRCm38) |
T112A |
probably benign |
Het |
| Tesk1 |
T |
A |
4: 43,445,368 (GRCm38) |
D230E |
probably damaging |
Het |
| Tm4sf5 |
C |
T |
11: 70,510,712 (GRCm38) |
A179V |
probably damaging |
Het |
| Tnr |
G |
T |
1: 159,852,416 (GRCm38) |
G320V |
probably damaging |
Het |
| Trappc11 |
A |
T |
8: 47,503,320 (GRCm38) |
C874S |
possibly damaging |
Het |
| Trpm3 |
T |
A |
19: 22,914,446 (GRCm38) |
Y885N |
probably damaging |
Het |
| Unc5a |
T |
A |
13: 55,002,879 (GRCm38) |
C505S |
probably damaging |
Het |
| Vmn1r28 |
G |
A |
6: 58,265,717 (GRCm38) |
A182T |
probably benign |
Het |
| Xpo5 |
T |
C |
17: 46,204,786 (GRCm38) |
|
probably benign |
Het |
| Zfp637 |
C |
A |
6: 117,845,668 (GRCm38) |
H252Q |
probably damaging |
Het |
| Zfp646 |
T |
A |
7: 127,880,731 (GRCm38) |
D693E |
probably damaging |
Het |
|
| Other mutations in Rims2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Rims2
|
APN |
15 |
39,459,615 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL00502:Rims2
|
APN |
15 |
39,506,984 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00556:Rims2
|
APN |
15 |
39,456,674 (GRCm38) |
splice site |
probably null |
|
|
IGL00811:Rims2
|
APN |
15 |
39,292,149 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00827:Rims2
|
APN |
15 |
39,472,359 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01642:Rims2
|
APN |
15 |
39,457,796 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02951:Rims2
|
APN |
15 |
39,534,938 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03009:Rims2
|
APN |
15 |
39,566,997 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL03080:Rims2
|
APN |
15 |
39,535,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03102:Rims2
|
APN |
15 |
39,459,593 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL03252:Rims2
|
APN |
15 |
39,452,352 (GRCm38) |
missense |
probably benign |
|
|
IGL03365:Rims2
|
APN |
15 |
39,476,541 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03393:Rims2
|
APN |
15 |
39,462,613 (GRCm38) |
splice site |
probably null |
|
|
IGL03409:Rims2
|
APN |
15 |
39,456,733 (GRCm38) |
missense |
probably damaging |
1.00 |
|
rhyme
|
UTSW |
15 |
39,452,328 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4486001:Rims2
|
UTSW |
15 |
39,476,520 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R0009:Rims2
|
UTSW |
15 |
39,534,966 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0078:Rims2
|
UTSW |
15 |
39,534,855 (GRCm38) |
missense |
probably benign |
0.42 |
|
R0367:Rims2
|
UTSW |
15 |
39,462,615 (GRCm38) |
splice site |
probably null |
|
|
R0401:Rims2
|
UTSW |
15 |
39,509,632 (GRCm38) |
splice site |
probably benign |
|
|
R0531:Rims2
|
UTSW |
15 |
39,567,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0791:Rims2
|
UTSW |
15 |
39,679,625 (GRCm38) |
splice site |
probably benign |
|
|
R0838:Rims2
|
UTSW |
15 |
39,681,025 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1201:Rims2
|
UTSW |
15 |
39,616,324 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1318:Rims2
|
UTSW |
15 |
39,517,826 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1457:Rims2
|
UTSW |
15 |
39,511,314 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1619:Rims2
|
UTSW |
15 |
39,506,986 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1672:Rims2
|
UTSW |
15 |
39,292,189 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1743:Rims2
|
UTSW |
15 |
39,679,650 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1766:Rims2
|
UTSW |
15 |
39,462,580 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1779:Rims2
|
UTSW |
15 |
39,681,702 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1804:Rims2
|
UTSW |
15 |
39,437,043 (GRCm38) |
nonsense |
probably null |
|
|
R1985:Rims2
|
UTSW |
15 |
39,345,314 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1986:Rims2
|
UTSW |
15 |
39,345,314 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2113:Rims2
|
UTSW |
15 |
39,511,326 (GRCm38) |
missense |
probably benign |
0.17 |
|
R2260:Rims2
|
UTSW |
15 |
39,478,566 (GRCm38) |
nonsense |
probably null |
|
|
R2510:Rims2
|
UTSW |
15 |
39,585,652 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3693:Rims2
|
UTSW |
15 |
39,478,575 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3937:Rims2
|
UTSW |
15 |
39,437,845 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4425:Rims2
|
UTSW |
15 |
39,437,924 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4453:Rims2
|
UTSW |
15 |
39,292,208 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4474:Rims2
|
UTSW |
15 |
39,462,560 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4518:Rims2
|
UTSW |
15 |
39,437,526 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Rims2
|
UTSW |
15 |
39,437,717 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4833:Rims2
|
UTSW |
15 |
39,535,914 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4936:Rims2
|
UTSW |
15 |
39,437,728 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4993:Rims2
|
UTSW |
15 |
39,454,445 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R5001:Rims2
|
UTSW |
15 |
39,452,428 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5054:Rims2
|
UTSW |
15 |
39,517,869 (GRCm38) |
splice site |
probably null |
|
|
R5072:Rims2
|
UTSW |
15 |
39,462,590 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5171:Rims2
|
UTSW |
15 |
39,437,103 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5429:Rims2
|
UTSW |
15 |
39,345,355 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5623:Rims2
|
UTSW |
15 |
39,478,615 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5624:Rims2
|
UTSW |
15 |
39,345,413 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R5685:Rims2
|
UTSW |
15 |
39,437,206 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R5784:Rims2
|
UTSW |
15 |
39,535,987 (GRCm38) |
splice site |
probably null |
|
|
R5790:Rims2
|
UTSW |
15 |
39,681,045 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5822:Rims2
|
UTSW |
15 |
39,476,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5963:Rims2
|
UTSW |
15 |
39,437,182 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5988:Rims2
|
UTSW |
15 |
39,292,182 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6057:Rims2
|
UTSW |
15 |
39,675,020 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6239:Rims2
|
UTSW |
15 |
39,198,363 (GRCm38) |
start codon destroyed |
unknown |
|
|
R6407:Rims2
|
UTSW |
15 |
39,452,328 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6418:Rims2
|
UTSW |
15 |
39,509,696 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6495:Rims2
|
UTSW |
15 |
39,517,812 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6502:Rims2
|
UTSW |
15 |
39,534,855 (GRCm38) |
missense |
probably benign |
0.42 |
|
R6753:Rims2
|
UTSW |
15 |
39,566,973 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R6855:Rims2
|
UTSW |
15 |
39,345,515 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6948:Rims2
|
UTSW |
15 |
39,511,341 (GRCm38) |
missense |
probably benign |
|
|
R7058:Rims2
|
UTSW |
15 |
39,585,648 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7167:Rims2
|
UTSW |
15 |
39,437,077 (GRCm38) |
missense |
probably benign |
|
|
R7217:Rims2
|
UTSW |
15 |
39,476,489 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7223:Rims2
|
UTSW |
15 |
39,437,032 (GRCm38) |
missense |
probably benign |
0.30 |
|
R7289:Rims2
|
UTSW |
15 |
39,437,718 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7459:Rims2
|
UTSW |
15 |
39,517,839 (GRCm38) |
missense |
probably benign |
|
|
R7663:Rims2
|
UTSW |
15 |
39,507,026 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7792:Rims2
|
UTSW |
15 |
39,198,528 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R7836:Rims2
|
UTSW |
15 |
39,681,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8082:Rims2
|
UTSW |
15 |
39,476,523 (GRCm38) |
missense |
probably benign |
0.34 |
|
R8489:Rims2
|
UTSW |
15 |
39,616,450 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8730:Rims2
|
UTSW |
15 |
39,517,843 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8830:Rims2
|
UTSW |
15 |
39,437,362 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R8857:Rims2
|
UTSW |
15 |
39,679,648 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8893:Rims2
|
UTSW |
15 |
39,534,954 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9010:Rims2
|
UTSW |
15 |
39,452,390 (GRCm38) |
nonsense |
probably null |
|
|
R9030:Rims2
|
UTSW |
15 |
39,476,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9287:Rims2
|
UTSW |
15 |
39,679,690 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9395:Rims2
|
UTSW |
15 |
39,292,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9451:Rims2
|
UTSW |
15 |
39,437,328 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9506:Rims2
|
UTSW |
15 |
39,472,436 (GRCm38) |
missense |
probably damaging |
0.97 |
|
X0034:Rims2
|
UTSW |
15 |
39,437,534 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,681,114 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Rims2
|
UTSW |
15 |
39,478,690 (GRCm38) |
frame shift |
probably null |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,437,769 (GRCm38) |
missense |
probably benign |
0.24 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTCTCCTTGTGGAAAGCAGGTAGC -3'
(R):5'- AGTCAGGACAGGATTGACTTAGGACTC -3'
Sequencing Primer
(F):5'- GCATCGCTTATAACTGAGCAAG -3'
(R):5'- ACTTAGGACTCCTGGTTAATGAG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation