Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02980:Zfp931'

406525

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp931

Ensembl Gene

ENSMUSG00000078861

Gene Name

zinc finger protein 931

Synonyms

2810021G02Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.113) question?

Stock #

IGL02980 (G1)

Quality Score

Status

Chromosome

Chromosomal Location

177709488-177720269 bp(-) (GRCm39)

Type of Mutation

critical splice acceptor site

DNA Base Change (assembly)

C to A at 177711409 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000104552 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000108923] [ENSMUST00000108924] [ENSMUST00000131702]

AlphaFold

A2AHM2

Predicted Effect

probably null
Transcript: ENSMUST00000108923

SMART Domains

Protein: ENSMUSP00000104551
Gene: ENSMUSG00000078861

Domain	Start	End	E-Value	Type
KRAB	4	64	2.27e-13	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000108924

SMART Domains

Protein: ENSMUSP00000104552
Gene: ENSMUSG00000078861

Domain	Start	End	E-Value	Type
KRAB	4	66	3.04e-14	SMART
ZnF_C2H2	78	97	2.63e2	SMART
ZnF_C2H2	103	125	1.2e-3	SMART
ZnF_C2H2	131	153	8.02e-5	SMART
ZnF_C2H2	159	181	2.12e-4	SMART
ZnF_C2H2	187	209	1.4e-4	SMART
ZnF_C2H2	215	237	2.99e-4	SMART
ZnF_C2H2	243	265	4.87e-4	SMART
ZnF_C2H2	271	293	7.49e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123265

Predicted Effect

probably benign
Transcript: ENSMUST00000131702

Coding Region Coverage

1x: 0.0%
3x: 0.0%
10x: 0.0%
20x: 0.0%

Validation Efficiency

97% (35/36)

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acvr1b	A	G	15: 101,100,959 (GRCm39)	R374G	probably damaging	Het
Adam28	A	T	14: 68,857,255 (GRCm39)	S584T	probably benign	Het
Akap1	A	T	11: 88,735,990 (GRCm39)	I224N	probably benign	Het
Ankdd1b	C	T	13: 96,572,448 (GRCm39)	R214Q	probably benign	Het
Armt1	A	G	10: 4,400,643 (GRCm39)		probably benign	Het
C1rl	T	C	6: 124,485,487 (GRCm39)	I286T	probably benign	Het
Cdh23	T	C	10: 60,150,399 (GRCm39)	T2528A	probably damaging	Het
Col4a4	A	G	1: 82,447,198 (GRCm39)		probably null	Het
Dag1	A	G	9: 108,095,237 (GRCm39)	I85T	probably benign	Het
Elf2	A	G	3: 51,172,379 (GRCm39)	V86A	possibly damaging	Het
Emsy	T	C	7: 98,268,587 (GRCm39)	T485A	probably damaging	Het
Fam169a	T	C	13: 97,250,188 (GRCm39)		probably null	Het
Hsd17b4	A	G	18: 50,279,585 (GRCm39)	H188R	probably benign	Het
Ighv9-2	C	T	12: 114,072,839 (GRCm39)	V45M	probably damaging	Het
Kifbp	A	C	10: 62,394,947 (GRCm39)	L565W	probably damaging	Het
Lama3	C	T	18: 12,686,288 (GRCm39)	L2784F	probably benign	Het
Ms4a4c	G	T	19: 11,393,747 (GRCm39)	A64S	probably benign	Het
Nudt22	A	G	19: 6,970,500 (GRCm39)	L280P	probably damaging	Het
Oscar	T	C	7: 3,614,062 (GRCm39)		probably benign	Het
Paics	A	G	5: 77,114,102 (GRCm39)	I321V	probably benign	Het
Pappa	A	T	4: 65,226,011 (GRCm39)	H1288L	probably benign	Het
Pla2r1	T	C	2: 60,345,390 (GRCm39)	E322G	possibly damaging	Het
Poldip2	T	A	11: 78,412,054 (GRCm39)	M330K	probably damaging	Het
Potefam1	G	A	2: 110,994,818 (GRCm39)	H232Y	unknown	Het
Recql5	T	C	11: 115,784,770 (GRCm39)		probably null	Het
Rnf145	A	G	11: 44,452,484 (GRCm39)	M488V	probably benign	Het
Rrp1b	T	A	17: 32,269,013 (GRCm39)	D170E	possibly damaging	Het
Slamf7	T	C	1: 171,468,566 (GRCm39)	S109G	possibly damaging	Het
Slf1	A	G	13: 77,192,123 (GRCm39)	S904P	possibly damaging	Het
St7	C	A	6: 17,749,545 (GRCm39)		probably benign	Het
Stk25	A	G	1: 93,555,390 (GRCm39)	S102P	probably damaging	Het
Supt6	C	T	11: 78,116,548 (GRCm39)	A659T	probably damaging	Het
Tdrp	A	C	8: 14,003,918 (GRCm39)	S140A	probably damaging	Het
Thbs3	A	G	3: 89,130,451 (GRCm39)	N527D	probably benign	Het
Tsnaxip1	G	T	8: 106,568,842 (GRCm39)	V444L	probably damaging	Het
U2af2	A	G	7: 5,071,042 (GRCm39)	I116V	probably benign	Het

Other mutations in Zfp931

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1391:Zfp931	UTSW	2	177,709,984 (GRCm39)	missense	probably benign	0.01
R1907:Zfp931	UTSW	2	177,711,684 (GRCm39)	missense	probably damaging	1.00
R2109:Zfp931	UTSW	2	177,711,651 (GRCm39)	missense	probably null	1.00
R2283:Zfp931	UTSW	2	177,711,714 (GRCm39)	missense	possibly damaging	0.93
R4038:Zfp931	UTSW	2	177,709,777 (GRCm39)	missense	possibly damaging	0.53
R4039:Zfp931	UTSW	2	177,709,777 (GRCm39)	missense	possibly damaging	0.53
R4867:Zfp931	UTSW	2	177,709,855 (GRCm39)	missense	probably damaging	1.00
R4893:Zfp931	UTSW	2	177,709,996 (GRCm39)	missense	probably damaging	0.99
R5593:Zfp931	UTSW	2	177,709,595 (GRCm39)	missense	possibly damaging	0.47
R7295:Zfp931	UTSW	2	177,709,824 (GRCm39)	nonsense	probably null
R8050:Zfp931	UTSW	2	177,709,889 (GRCm39)	missense	probably damaging	1.00
R8069:Zfp931	UTSW	2	177,709,709 (GRCm39)	missense	probably benign	0.00
R8432:Zfp931	UTSW	2	177,711,346 (GRCm39)	makesense	probably null
R8806:Zfp931	UTSW	2	177,709,589 (GRCm39)	missense	possibly damaging	0.66
R8866:Zfp931	UTSW	2	177,710,178 (GRCm39)	nonsense	probably null
R8987:Zfp931	UTSW	2	177,709,592 (GRCm39)	missense	probably damaging	1.00
R8987:Zfp931	UTSW	2	177,709,591 (GRCm39)	missense	probably damaging	1.00
R9088:Zfp931	UTSW	2	177,709,594 (GRCm39)	missense	probably damaging	1.00
R9538:Zfp931	UTSW	2	177,709,605 (GRCm39)	missense	probably benign	0.04

Posted On

2016-08-02