Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02999:Gm14085'

407256

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm14085

Ensembl Gene

ENSMUSG00000079071

Gene Name

predicted gene 14085

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL02999

Quality Score

Status

Chromosome

Chromosomal Location

122484941-122528040 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 122514514 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000106150 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000110521]

AlphaFold

A2AWR5

Predicted Effect

probably benign
Transcript: ENSMUST00000110521

SMART Domains

Protein: ENSMUSP00000106150
Gene: ENSMUSG00000079071

Domain	Start	End	E-Value	Type
transmembrane domain	76	98	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	149	166	N/A	INTRINSIC
Pfam:Nucleos_tra2_N	180	253	2.3e-28	PFAM
Pfam:Gate	260	360	1.7e-10	PFAM
Pfam:Nucleos_tra2_C	363	587	4.6e-70	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610008E11Rik	T	A	10: 79,067,590	R297S	possibly damaging	Het
Abca13	G	A	11: 9,581,757		probably benign	Het
Acot12	T	A	13: 91,759,981	V94D	probably damaging	Het
Adgrv1	C	T	13: 81,578,854	A460T	probably benign	Het
Atp8a2	C	A	14: 59,925,122	E717*	probably null	Het
Brinp3	A	T	1: 146,701,849		probably null	Het
Camk1d	C	A	2: 5,354,705	V177L	probably benign	Het
Chst11	A	G	10: 83,191,704	I322V	possibly damaging	Het
Cobl	T	C	11: 12,343,869	T296A	possibly damaging	Het
Dcc	A	C	18: 71,378,678	F869V	possibly damaging	Het
Dock2	G	T	11: 34,692,259	T609K	probably damaging	Het
Ercc5	A	G	1: 44,167,654	T576A	probably benign	Het
Faf1	A	G	4: 109,861,893	I399V	probably benign	Het
Fndc3b	T	G	3: 27,538,239	E170A	probably damaging	Het
Ggt7	C	A	2: 155,502,713	V237L	probably benign	Het
Hectd1	G	T	12: 51,827,422	Q24K	possibly damaging	Het
Krt19	T	C	11: 100,141,409		probably benign	Het
Lilrb4a	T	C	10: 51,494,143	L259P	probably damaging	Het
Limd1	T	C	9: 123,516,799	Y548H	probably damaging	Het
Lingo2	A	G	4: 35,708,744	I412T	probably damaging	Het
Lrrc34	T	A	3: 30,634,633	Q173L	probably damaging	Het
Lrrn3	A	T	12: 41,452,751	N522K	probably benign	Het
Mgat4e	A	C	1: 134,541,190	L372R	probably damaging	Het
Nedd4l	A	G	18: 65,198,707	D638G	probably damaging	Het
Olfm3	T	C	3: 115,122,748	M423T	probably damaging	Het
Olfr969	T	C	9: 39,795,456	L27P	probably damaging	Het
Pcsk7	T	A	9: 45,927,599	I603N	possibly damaging	Het
Ptpn2	A	G	18: 67,681,510	V143A	probably damaging	Het
Rabgap1	C	A	2: 37,483,826	D283E	possibly damaging	Het
Reln	G	A	5: 21,995,365	S1379F	probably damaging	Het
Rpap2	T	A	5: 107,601,831	F74I	possibly damaging	Het
Sel1l2	T	C	2: 140,230,804	E637G	probably damaging	Het
St18	T	A	1: 6,817,605	V466E	probably benign	Het
Stac	C	A	9: 111,604,130	G207C	probably damaging	Het
Stra6	T	A	9: 58,135,113	N8K	probably benign	Het
Sytl4	C	T	X: 133,937,978	R649Q	probably benign	Het
Tas1r3	A	G	4: 155,862,359	V263A	probably damaging	Het
Tprg	T	C	16: 25,317,468	Y70H	probably damaging	Het

Other mutations in Gm14085

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00964:Gm14085	APN	2	122517046	missense	probably damaging	0.98
IGL01160:Gm14085	APN	2	122524796	critical splice acceptor site	probably null
IGL01838:Gm14085	APN	2	122517983	missense	possibly damaging	0.65
IGL01895:Gm14085	APN	2	122525091	missense	possibly damaging	0.75
Wilted	UTSW	2	122523482	missense	probably damaging	1.00
K2124:Gm14085	UTSW	2	122525153	missense	probably benign	0.00
R0084:Gm14085	UTSW	2	122522833	missense	possibly damaging	0.95
R0092:Gm14085	UTSW	2	122517597	splice site	probably benign
R0127:Gm14085	UTSW	2	122517069	critical splice donor site	probably null
R0200:Gm14085	UTSW	2	122527447	makesense	probably null
R0276:Gm14085	UTSW	2	122521928	missense	probably damaging	1.00
R0309:Gm14085	UTSW	2	122517553	missense	probably benign	0.04
R0403:Gm14085	UTSW	2	122521854	missense	probably damaging	1.00
R0600:Gm14085	UTSW	2	122514398	missense	probably damaging	0.97
R0612:Gm14085	UTSW	2	122521698	missense	probably damaging	1.00
R1676:Gm14085	UTSW	2	122521859	missense	probably damaging	0.99
R1801:Gm14085	UTSW	2	122521652	missense	possibly damaging	0.57
R1986:Gm14085	UTSW	2	122527429	missense	probably benign	0.00
R2050:Gm14085	UTSW	2	122522868	missense	probably benign	0.21
R3078:Gm14085	UTSW	2	122514414	missense	possibly damaging	0.63
R4075:Gm14085	UTSW	2	122514411	missense	probably benign	0.00
R4096:Gm14085	UTSW	2	122522728	missense	probably damaging	1.00
R4744:Gm14085	UTSW	2	122522805	nonsense	probably null
R4796:Gm14085	UTSW	2	122514459	missense	probably damaging	0.99
R5033:Gm14085	UTSW	2	122522914	critical splice donor site	probably null
R5069:Gm14085	UTSW	2	122494373	missense	possibly damaging	0.93
R5288:Gm14085	UTSW	2	122522778	missense	probably benign	0.01
R5385:Gm14085	UTSW	2	122522778	missense	probably benign	0.01
R5386:Gm14085	UTSW	2	122522778	missense	probably benign	0.01
R5442:Gm14085	UTSW	2	122486869	missense	probably benign
R5795:Gm14085	UTSW	2	122517994	missense	possibly damaging	0.79
R6258:Gm14085	UTSW	2	122523482	missense	probably damaging	1.00
R6260:Gm14085	UTSW	2	122523482	missense	probably damaging	1.00
R6383:Gm14085	UTSW	2	122524807	missense	probably benign	0.00
R7226:Gm14085	UTSW	2	122522532	missense	probably benign	0.00
R7574:Gm14085	UTSW	2	122522844	missense	not run
R7633:Gm14085	UTSW	2	122486680	missense	probably null	0.05
R7705:Gm14085	UTSW	2	122521629	critical splice acceptor site	probably null
R7726:Gm14085	UTSW	2	122486733	missense	probably damaging	0.99
R7998:Gm14085	UTSW	2	122494358	missense	probably damaging	0.97
R8269:Gm14085	UTSW	2	122521688	missense	probably damaging	1.00
R8337:Gm14085	UTSW	2	122525136	missense	probably benign	0.06
R8546:Gm14085	UTSW	2	122522754	missense	probably benign	0.14
R8817:Gm14085	UTSW	2	122518507	missense	possibly damaging	0.95
R8931:Gm14085	UTSW	2	122518502	missense
R9070:Gm14085	UTSW	2	122521673	missense	probably damaging	1.00
R9542:Gm14085	UTSW	2	122494341	missense	probably benign	0.26
R9702:Gm14085	UTSW	2	122523531	missense	probably damaging	1.00
R9782:Gm14085	UTSW	2	122521857	missense	probably damaging	1.00

Posted On

2016-08-02