Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03003:Ptprz1'

407429

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ptprz1

Ensembl Gene

ENSMUSG00000068748

Gene Name

protein tyrosine phosphatase, receptor type Z, polypeptide 1

Synonyms

PTPzeta, RPTPz, phosphacan, Rptpbeta, DSD-1-PG, PTPbeta, Ptprz, Ptpz

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.619) question?

Stock #

IGL03003

Quality Score

Status

Chromosome

Chromosomal Location

22875502-23052916 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 23002583 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 1557 (N1557K)

Ref Sequence

ENSEMBL: ENSMUSP00000144605 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090568] [ENSMUST00000202102] [ENSMUST00000202579]

AlphaFold

B9EKR1

Predicted Effect

possibly damaging
Transcript: ENSMUST00000090568
AA Change: N1557K

PolyPhen 2 Score 0.892 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000088056
Gene: ENSMUSG00000068748
AA Change: N1557K

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC
Blast:PTPc	1497	1573	1e-12	BLAST
low complexity region	1606	1620	N/A	INTRINSIC
transmembrane domain	1637	1659	N/A	INTRINSIC
low complexity region	1679	1693	N/A	INTRINSIC
PTPc	1720	1991	2.8e-130	SMART
PTPc	2019	2281	1.65e-77	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000201827

Predicted Effect

probably benign
Transcript: ENSMUST00000202102

SMART Domains

Protein: ENSMUSP00000143902
Gene: ENSMUSG00000068748

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
transmembrane domain	788	810	N/A	INTRINSIC
low complexity region	830	844	N/A	INTRINSIC
PTPc	871	1142	2.8e-130	SMART
PTPc	1170	1432	1.65e-77	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000202579
AA Change: N1557K

PolyPhen 2 Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000144605
Gene: ENSMUSG00000068748
AA Change: N1557K

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Carb_anhydrase	38	300	4e-103	SMART
FN3	312	397	2.8e-6	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
PHENOTYPE: Mice homozygous for targeted null mutations demonstrate an impaired ability to recover from inflamatory lesions of the CNS or gastric mucosa. Mice homozygous for a knock-out allele exhibit increased tactile and thermal nociception thresholds. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AA986860	C	T	1: 130,743,772 (GRCm38)	P577L	probably damaging	Het
Aff3	A	T	1: 38,209,570 (GRCm38)	S819T	probably damaging	Het
Aftph	G	T	11: 20,726,982 (GRCm38)	S209*	probably null	Het
Astn1	T	A	1: 158,612,395 (GRCm38)	D844E	probably benign	Het
Cc2d2a	A	G	5: 43,671,266 (GRCm38)	K29E	probably benign	Het
Ccdc93	T	C	1: 121,463,117 (GRCm38)	S273P	possibly damaging	Het
Cd200r3	C	A	16: 44,943,776 (GRCm38)	H2N	probably benign	Het
Cd200r3	G	T	16: 44,943,775 (GRCm38)	M1I	probably null	Het
Col7a1	G	A	9: 108,974,956 (GRCm38)		probably null	Het
Cyp3a41a	T	A	5: 145,705,830 (GRCm38)	M240L	probably benign	Het
D430042O09Rik	A	T	7: 125,851,960 (GRCm38)	I1088F	probably damaging	Het
Dcstamp	T	C	15: 39,754,510 (GRCm38)	V105A	possibly damaging	Het
Dmbt1	C	A	7: 131,082,679 (GRCm38)	P635Q	probably benign	Het
Dsg1a	T	A	18: 20,336,819 (GRCm38)	M634K	probably benign	Het
Farp2	T	C	1: 93,567,418 (GRCm38)	Y138H	probably damaging	Het
Fga	T	C	3: 83,032,730 (GRCm38)	S564P	probably damaging	Het
Gbf1	T	C	19: 46,255,655 (GRCm38)	L142S	probably damaging	Het
Gm5422	T	C	10: 31,250,844 (GRCm38)		noncoding transcript	Het
Helz2	A	G	2: 181,240,253 (GRCm38)	V249A	probably damaging	Het
Hmcn2	C	A	2: 31,433,486 (GRCm38)	T4204K	probably damaging	Het
Ift81	T	C	5: 122,594,662 (GRCm38)	I270V	probably benign	Het
Kif6	C	T	17: 49,753,871 (GRCm38)	R411*	probably null	Het
Klhl35	T	A	7: 99,470,343 (GRCm38)	V345D	probably damaging	Het
Mcm3ap	C	A	10: 76,504,697 (GRCm38)	D1531E	probably benign	Het
Muc5b	C	A	7: 141,863,614 (GRCm38)	D3432E	probably benign	Het
Nipbl	A	T	15: 8,350,314 (GRCm38)	V998D	probably damaging	Het
Nlrc3	C	A	16: 3,964,862 (GRCm38)	V228L	probably benign	Het
Nrap	T	C	19: 56,321,952 (GRCm38)	H1456R	probably damaging	Het
Nt5c1b	C	T	12: 10,374,910 (GRCm38)	A210V	possibly damaging	Het
Olfr364-ps1	T	C	2: 37,146,452 (GRCm38)	V80A	probably benign	Het
Olfr46	A	G	7: 140,610,370 (GRCm38)	Y60C	probably damaging	Het
Osbpl7	T	C	11: 97,050,695 (GRCm38)	Y15H	probably benign	Het
Pde8b	T	A	13: 95,041,957 (GRCm38)	N552Y	probably damaging	Het
Pi4kb	T	A	3: 94,984,812 (GRCm38)	S280T	probably benign	Het
Pkd1	T	A	17: 24,593,603 (GRCm38)		probably null	Het
Polh	A	T	17: 46,194,366 (GRCm38)	V108E	possibly damaging	Het
Prob1	A	G	18: 35,653,375 (GRCm38)	S609P	possibly damaging	Het
Rev1	A	C	1: 38,088,073 (GRCm38)	F369V	possibly damaging	Het
Rgma	A	G	7: 73,417,440 (GRCm38)	N148D	probably damaging	Het
Robo3	A	G	9: 37,419,291 (GRCm38)	L1003S	probably damaging	Het
Sdhb	T	C	4: 140,973,000 (GRCm38)	V137A	probably damaging	Het
Sema6c	T	C	3: 95,169,614 (GRCm38)	L337P	probably damaging	Het
Shc4	A	T	2: 125,723,333 (GRCm38)	Y15*	probably null	Het
Slc4a9	T	C	18: 36,536,893 (GRCm38)	S722P	probably damaging	Het
Smarcc1	A	G	9: 110,206,100 (GRCm38)	N864D	probably damaging	Het
Sspo	T	C	6: 48,455,087 (GRCm38)	L745P	probably damaging	Het
Syce1l	A	G	8: 113,654,067 (GRCm38)	D137G	probably damaging	Het
Tbc1d1	G	T	5: 64,316,438 (GRCm38)	W768L	probably damaging	Het
Tmbim7	A	G	5: 3,661,887 (GRCm38)	D7G	probably benign	Het
Tmem109	A	C	19: 10,874,331 (GRCm38)	S64A	probably benign	Het
Tnfrsf21	A	G	17: 43,039,943 (GRCm38)	R333G	probably damaging	Het
Ttn	T	G	2: 76,781,611 (GRCm38)	S17316R	probably damaging	Het
Usp10	A	G	8: 119,954,810 (GRCm38)	T668A	possibly damaging	Het
Xirp2	T	A	2: 67,515,562 (GRCm38)	F2716I	possibly damaging	Het

Other mutations in Ptprz1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00486:Ptprz1	APN	6	22,973,054 (GRCm38)	missense	probably damaging	1.00
IGL00773:Ptprz1	APN	6	23,002,629 (GRCm38)	missense	probably benign	0.41
IGL01458:Ptprz1	APN	6	22,972,844 (GRCm38)	missense	probably damaging	0.99
IGL01481:Ptprz1	APN	6	22,999,980 (GRCm38)	missense	probably benign	0.05
IGL01501:Ptprz1	APN	6	22,973,082 (GRCm38)	missense	probably damaging	1.00
IGL01601:Ptprz1	APN	6	23,000,438 (GRCm38)	missense	probably damaging	0.99
IGL01882:Ptprz1	APN	6	23,000,464 (GRCm38)	missense	probably damaging	1.00
IGL02058:Ptprz1	APN	6	23,002,503 (GRCm38)	missense	probably benign	0.00
IGL02089:Ptprz1	APN	6	23,033,448 (GRCm38)	missense	probably damaging	1.00
IGL02136:Ptprz1	APN	6	22,972,822 (GRCm38)	missense	probably damaging	1.00
IGL02215:Ptprz1	APN	6	22,965,182 (GRCm38)	missense	possibly damaging	0.91
IGL02220:Ptprz1	APN	6	23,042,743 (GRCm38)	splice site	probably benign
IGL02556:Ptprz1	APN	6	22,972,845 (GRCm38)	missense	probably benign	0.01
IGL02601:Ptprz1	APN	6	23,000,687 (GRCm38)	missense	probably benign	0.11
IGL02620:Ptprz1	APN	6	22,959,740 (GRCm38)	missense	probably damaging	1.00
IGL02666:Ptprz1	APN	6	23,001,210 (GRCm38)	missense	probably benign	0.00
IGL02718:Ptprz1	APN	6	23,001,349 (GRCm38)	missense	possibly damaging	0.77
IGL02792:Ptprz1	APN	6	22,959,723 (GRCm38)	missense	probably damaging	1.00
IGL02894:Ptprz1	APN	6	23,035,149 (GRCm38)	missense	probably damaging	1.00
IGL02952:Ptprz1	APN	6	23,036,926 (GRCm38)	missense	probably damaging	1.00
IGL03060:Ptprz1	APN	6	22,972,835 (GRCm38)	missense	probably damaging	1.00
IGL03170:Ptprz1	APN	6	22,959,767 (GRCm38)	missense	probably benign	0.00
IGL03246:Ptprz1	APN	6	22,986,160 (GRCm38)	missense	probably damaging	0.99
IGL03349:Ptprz1	APN	6	23,000,332 (GRCm38)	missense	probably damaging	1.00
IGL03365:Ptprz1	APN	6	23,030,582 (GRCm38)	splice site	probably benign
Elevator	UTSW	6	23,030,662 (GRCm38)	missense	probably benign	0.03
escalator	UTSW	6	22,986,188 (GRCm38)	missense	probably damaging	1.00
R0044:Ptprz1	UTSW	6	23,007,403 (GRCm38)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,196 (GRCm38)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,196 (GRCm38)	missense	probably damaging	1.00
R0107:Ptprz1	UTSW	6	23,000,570 (GRCm38)	missense	probably damaging	0.98
R0278:Ptprz1	UTSW	6	23,000,817 (GRCm38)	missense	probably benign	0.31
R0345:Ptprz1	UTSW	6	23,016,165 (GRCm38)	missense	probably damaging	1.00
R0359:Ptprz1	UTSW	6	22,973,176 (GRCm38)	splice site	probably benign
R0743:Ptprz1	UTSW	6	23,044,367 (GRCm38)	nonsense	probably null
R1014:Ptprz1	UTSW	6	23,000,644 (GRCm38)	missense	probably damaging	1.00
R1016:Ptprz1	UTSW	6	23,000,974 (GRCm38)	missense	probably damaging	1.00
R1106:Ptprz1	UTSW	6	22,965,749 (GRCm38)	missense	probably damaging	0.99
R1391:Ptprz1	UTSW	6	23,001,729 (GRCm38)	missense	probably benign	0.33
R1424:Ptprz1	UTSW	6	23,000,383 (GRCm38)	missense	probably benign	0.00
R1445:Ptprz1	UTSW	6	23,050,474 (GRCm38)	missense	probably damaging	1.00
R1496:Ptprz1	UTSW	6	23,049,524 (GRCm38)	splice site	probably benign
R1544:Ptprz1	UTSW	6	23,000,748 (GRCm38)	missense	possibly damaging	0.63
R1626:Ptprz1	UTSW	6	23,001,574 (GRCm38)	missense	probably benign
R1641:Ptprz1	UTSW	6	23,049,606 (GRCm38)	missense	probably damaging	1.00
R1757:Ptprz1	UTSW	6	23,044,320 (GRCm38)	missense	probably damaging	1.00
R1812:Ptprz1	UTSW	6	22,959,712 (GRCm38)	missense	probably benign	0.07
R1917:Ptprz1	UTSW	6	23,035,040 (GRCm38)	splice site	probably benign
R1930:Ptprz1	UTSW	6	23,007,355 (GRCm38)	missense	probably damaging	1.00
R1931:Ptprz1	UTSW	6	23,007,355 (GRCm38)	missense	probably damaging	1.00
R1974:Ptprz1	UTSW	6	22,986,311 (GRCm38)	missense	probably damaging	1.00
R1992:Ptprz1	UTSW	6	22,959,748 (GRCm38)	missense	probably benign	0.24
R1997:Ptprz1	UTSW	6	23,050,497 (GRCm38)	missense	probably damaging	0.99
R2002:Ptprz1	UTSW	6	23,027,834 (GRCm38)	nonsense	probably null
R2012:Ptprz1	UTSW	6	23,001,027 (GRCm38)	missense	probably benign	0.03
R2059:Ptprz1	UTSW	6	22,986,323 (GRCm38)	splice site	probably benign
R2061:Ptprz1	UTSW	6	23,049,675 (GRCm38)	critical splice donor site	probably null
R2064:Ptprz1	UTSW	6	23,050,389 (GRCm38)	splice site	probably benign
R2067:Ptprz1	UTSW	6	23,050,389 (GRCm38)	splice site	probably benign
R2108:Ptprz1	UTSW	6	23,033,477 (GRCm38)	missense	probably damaging	0.99
R2152:Ptprz1	UTSW	6	23,030,671 (GRCm38)	missense	probably damaging	0.99
R2166:Ptprz1	UTSW	6	23,045,633 (GRCm38)	missense	possibly damaging	0.90
R2183:Ptprz1	UTSW	6	23,002,285 (GRCm38)	missense	probably benign
R2202:Ptprz1	UTSW	6	23,000,650 (GRCm38)	missense	possibly damaging	0.63
R2238:Ptprz1	UTSW	6	22,987,377 (GRCm38)	missense	probably damaging	1.00
R2290:Ptprz1	UTSW	6	23,000,991 (GRCm38)	missense	probably damaging	1.00
R3027:Ptprz1	UTSW	6	23,016,197 (GRCm38)	missense	possibly damaging	0.89
R3861:Ptprz1	UTSW	6	23,036,895 (GRCm38)	missense	probably damaging	0.98
R4012:Ptprz1	UTSW	6	23,002,585 (GRCm38)	missense	probably damaging	0.99
R4020:Ptprz1	UTSW	6	22,959,624 (GRCm38)	splice site	probably benign
R4158:Ptprz1	UTSW	6	23,022,205 (GRCm38)	missense	possibly damaging	0.73
R4158:Ptprz1	UTSW	6	23,001,684 (GRCm38)	nonsense	probably null
R4159:Ptprz1	UTSW	6	23,001,684 (GRCm38)	nonsense	probably null
R4160:Ptprz1	UTSW	6	23,022,205 (GRCm38)	missense	possibly damaging	0.73
R4606:Ptprz1	UTSW	6	23,001,487 (GRCm38)	missense	possibly damaging	0.80
R4621:Ptprz1	UTSW	6	23,001,454 (GRCm38)	missense	possibly damaging	0.68
R4640:Ptprz1	UTSW	6	22,972,798 (GRCm38)	missense	probably damaging	1.00
R4731:Ptprz1	UTSW	6	23,002,610 (GRCm38)	missense	probably benign	0.06
R4732:Ptprz1	UTSW	6	23,002,610 (GRCm38)	missense	probably benign	0.06
R4733:Ptprz1	UTSW	6	23,002,610 (GRCm38)	missense	probably benign	0.06
R4803:Ptprz1	UTSW	6	23,001,546 (GRCm38)	missense	probably benign	0.00
R4890:Ptprz1	UTSW	6	23,024,958 (GRCm38)	missense	probably damaging	1.00
R5035:Ptprz1	UTSW	6	23,016,215 (GRCm38)	missense	probably benign	0.06
R5052:Ptprz1	UTSW	6	23,045,626 (GRCm38)	missense	probably damaging	1.00
R5106:Ptprz1	UTSW	6	23,000,028 (GRCm38)	missense	probably benign	0.04
R5248:Ptprz1	UTSW	6	23,001,901 (GRCm38)	missense	probably benign	0.11
R5292:Ptprz1	UTSW	6	23,002,582 (GRCm38)	missense	probably benign	0.31
R5373:Ptprz1	UTSW	6	23,007,355 (GRCm38)	missense	probably damaging	1.00
R5374:Ptprz1	UTSW	6	23,007,355 (GRCm38)	missense	probably damaging	1.00
R5378:Ptprz1	UTSW	6	23,007,402 (GRCm38)	missense	probably damaging	1.00
R5408:Ptprz1	UTSW	6	23,002,600 (GRCm38)	missense	probably damaging	1.00
R5479:Ptprz1	UTSW	6	23,001,666 (GRCm38)	missense	probably benign
R5524:Ptprz1	UTSW	6	22,986,318 (GRCm38)	splice site	probably null
R5527:Ptprz1	UTSW	6	23,000,053 (GRCm38)	missense	possibly damaging	0.66
R5557:Ptprz1	UTSW	6	23,001,001 (GRCm38)	missense	probably benign	0.04
R5654:Ptprz1	UTSW	6	22,986,134 (GRCm38)	missense	probably damaging	1.00
R5655:Ptprz1	UTSW	6	22,999,773 (GRCm38)	missense	probably benign	0.00
R5658:Ptprz1	UTSW	6	23,016,189 (GRCm38)	missense	probably damaging	1.00
R5663:Ptprz1	UTSW	6	23,035,143 (GRCm38)	missense	probably damaging	1.00
R5765:Ptprz1	UTSW	6	23,000,236 (GRCm38)	missense	probably damaging	1.00
R5822:Ptprz1	UTSW	6	23,001,445 (GRCm38)	missense	probably benign	0.01
R5837:Ptprz1	UTSW	6	23,001,418 (GRCm38)	missense	probably benign	0.00
R6108:Ptprz1	UTSW	6	23,045,659 (GRCm38)	missense	probably damaging	1.00
R6199:Ptprz1	UTSW	6	23,002,471 (GRCm38)	missense	probably benign	0.01
R6245:Ptprz1	UTSW	6	23,051,990 (GRCm38)	missense	probably damaging	1.00
R6257:Ptprz1	UTSW	6	22,959,640 (GRCm38)	missense	probably damaging	1.00
R6488:Ptprz1	UTSW	6	23,001,517 (GRCm38)	nonsense	probably null
R6606:Ptprz1	UTSW	6	23,002,501 (GRCm38)	missense	probably benign	0.27
R6612:Ptprz1	UTSW	6	23,052,082 (GRCm38)	missense	probably damaging	1.00
R6824:Ptprz1	UTSW	6	23,002,131 (GRCm38)	missense	probably benign	0.05
R6834:Ptprz1	UTSW	6	22,999,633 (GRCm38)	missense	probably benign	0.38
R6836:Ptprz1	UTSW	6	23,030,665 (GRCm38)	nonsense	probably null
R6991:Ptprz1	UTSW	6	23,002,687 (GRCm38)	missense	probably benign	0.00
R7044:Ptprz1	UTSW	6	23,044,346 (GRCm38)	missense	probably damaging	1.00
R7048:Ptprz1	UTSW	6	22,961,623 (GRCm38)	missense	probably benign	0.18
R7225:Ptprz1	UTSW	6	23,000,929 (GRCm38)	missense	possibly damaging	0.61
R7284:Ptprz1	UTSW	6	23,000,098 (GRCm38)	missense	probably damaging	1.00
R7360:Ptprz1	UTSW	6	23,000,907 (GRCm38)	missense	probably damaging	1.00
R7501:Ptprz1	UTSW	6	23,001,747 (GRCm38)	nonsense	probably null
R7515:Ptprz1	UTSW	6	23,022,267 (GRCm38)	missense	probably damaging	1.00
R7538:Ptprz1	UTSW	6	22,999,896 (GRCm38)	missense	possibly damaging	0.81
R7567:Ptprz1	UTSW	6	22,959,780 (GRCm38)	missense	probably damaging	0.97
R7599:Ptprz1	UTSW	6	23,002,519 (GRCm38)	missense	not run
R7611:Ptprz1	UTSW	6	23,001,220 (GRCm38)	missense	probably benign
R7685:Ptprz1	UTSW	6	23,024,978 (GRCm38)	missense	probably damaging	1.00
R7707:Ptprz1	UTSW	6	23,002,296 (GRCm38)	missense	probably benign	0.00
R7733:Ptprz1	UTSW	6	23,000,384 (GRCm38)	missense	probably benign	0.31
R7786:Ptprz1	UTSW	6	23,036,993 (GRCm38)	missense	probably damaging	1.00
R7868:Ptprz1	UTSW	6	23,000,964 (GRCm38)	missense	not run
R7882:Ptprz1	UTSW	6	23,002,257 (GRCm38)	missense	probably benign	0.13
R7968:Ptprz1	UTSW	6	22,959,676 (GRCm38)	missense	probably damaging	0.98
R8024:Ptprz1	UTSW	6	23,042,751 (GRCm38)	missense	probably damaging	1.00
R8157:Ptprz1	UTSW	6	23,002,540 (GRCm38)	missense	probably damaging	1.00
R8159:Ptprz1	UTSW	6	23,001,663 (GRCm38)	missense	probably benign
R8354:Ptprz1	UTSW	6	22,999,615 (GRCm38)	missense	probably damaging	0.99
R8496:Ptprz1	UTSW	6	22,972,798 (GRCm38)	missense	probably damaging	0.96
R8757:Ptprz1	UTSW	6	22,972,717 (GRCm38)	missense	possibly damaging	0.74
R8767:Ptprz1	UTSW	6	22,986,188 (GRCm38)	missense	probably damaging	1.00
R8783:Ptprz1	UTSW	6	23,002,027 (GRCm38)	missense	probably benign	0.00
R8811:Ptprz1	UTSW	6	23,030,662 (GRCm38)	missense	probably benign	0.03
R8817:Ptprz1	UTSW	6	23,007,372 (GRCm38)	missense	probably damaging	1.00
R8822:Ptprz1	UTSW	6	23,002,589 (GRCm38)	missense	probably damaging	0.98
R8874:Ptprz1	UTSW	6	23,042,748 (GRCm38)	missense
R9009:Ptprz1	UTSW	6	23,001,654 (GRCm38)	missense	possibly damaging	0.94
R9126:Ptprz1	UTSW	6	23,002,335 (GRCm38)	nonsense	probably null
R9201:Ptprz1	UTSW	6	22,972,870 (GRCm38)	critical splice donor site	probably null
R9210:Ptprz1	UTSW	6	23,050,494 (GRCm38)	missense	probably damaging	0.99
R9212:Ptprz1	UTSW	6	23,050,494 (GRCm38)	missense	probably damaging	0.99
R9229:Ptprz1	UTSW	6	22,986,284 (GRCm38)	missense	probably null	0.03
R9279:Ptprz1	UTSW	6	23,002,445 (GRCm38)	missense	probably benign
R9336:Ptprz1	UTSW	6	23,000,856 (GRCm38)	missense	probably benign	0.01
R9372:Ptprz1	UTSW	6	23,045,707 (GRCm38)	missense	probably damaging	1.00
R9577:Ptprz1	UTSW	6	23,002,203 (GRCm38)	missense	probably damaging	1.00
R9594:Ptprz1	UTSW	6	23,025,027 (GRCm38)	missense	probably damaging	0.98
R9632:Ptprz1	UTSW	6	23,007,293 (GRCm38)	missense	probably damaging	1.00
R9636:Ptprz1	UTSW	6	22,999,995 (GRCm38)	missense	probably benign
R9657:Ptprz1	UTSW	6	23,042,378 (GRCm38)	missense	possibly damaging	0.92
R9694:Ptprz1	UTSW	6	22,959,695 (GRCm38)	missense	probably damaging	1.00
R9716:Ptprz1	UTSW	6	22,959,651 (GRCm38)	missense	probably damaging	1.00
R9794:Ptprz1	UTSW	6	23,000,205 (GRCm38)	missense	probably benign	0.00
Z1176:Ptprz1	UTSW	6	23,051,995 (GRCm38)	missense	probably damaging	0.99
Z1177:Ptprz1	UTSW	6	23,052,024 (GRCm38)	missense	probably damaging	1.00
Z1177:Ptprz1	UTSW	6	22,999,840 (GRCm38)	missense	possibly damaging	0.51

Posted On

2016-08-02