Incidental Mutation 'IGL03017:Vmn2r39'
ID407918
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r39
Ensembl Gene ENSMUSG00000096658
Gene Namevomeronasal 2, receptor 39
SynonymsEG545909
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.107) question?
Stock #IGL03017
Quality Score
Status
Chromosome7
Chromosomal Location9013875-9030798 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 9014941 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Aspartic acid at position 799 (Y799D)
Ref Sequence ENSEMBL: ENSMUSP00000134010 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000174388]
Predicted Effect probably damaging
Transcript: ENSMUST00000174388
AA Change: Y799D

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000134010
Gene: ENSMUSG00000096658
AA Change: Y799D

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 73 469 9.1e-32 PFAM
Pfam:NCD3G 512 565 7.9e-21 PFAM
Pfam:7tm_3 598 833 2.6e-55 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arhgef11 C A 3: 87,717,060 Y519* probably null Het
Arhgef26 T A 3: 62,448,281 M758K possibly damaging Het
Ccdc187 T C 2: 26,280,966 Y500C probably benign Het
Cul5 A T 9: 53,644,485 probably null Het
Dnah5 A C 15: 28,340,325 I2293L possibly damaging Het
Emilin3 G A 2: 160,908,729 Q320* probably null Het
Gpr45 C T 1: 43,032,356 T53M possibly damaging Het
Hoxd3 T A 2: 74,746,706 M310K possibly damaging Het
Mtr A G 13: 12,247,891 probably null Het
Mup4 T A 4: 59,957,890 N171I probably damaging Het
Myo15b T A 11: 115,887,917 I1157N possibly damaging Het
Myo1d C T 11: 80,601,626 V768I probably benign Het
Nlrp4c T C 7: 6,084,680 C771R probably benign Het
Olfr390 C A 11: 73,787,518 H193Q probably benign Het
Patj G A 4: 98,465,027 probably benign Het
Pkp3 C A 7: 141,083,370 A376D probably benign Het
Pkp4 T C 2: 59,266,425 V57A probably benign Het
Poteg A T 8: 27,462,041 K232N probably benign Het
Psat1 G T 19: 15,917,135 A168E possibly damaging Het
Rassf8 T A 6: 145,817,198 probably null Het
Slc37a3 T A 6: 39,349,381 I281L probably benign Het
Sncaip A T 18: 52,894,937 H466L possibly damaging Het
Ttn T C 2: 76,868,302 T30A possibly damaging Het
Ttn T C 2: 76,787,116 E16337G probably damaging Het
Usp13 G A 3: 32,915,712 M662I possibly damaging Het
Vmn2r111 A T 17: 22,570,858 M389K probably damaging Het
Other mutations in Vmn2r39
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02059:Vmn2r39 APN 7 9023644 missense probably benign 0.19
R1314:Vmn2r39 UTSW 7 9014982 missense probably damaging 1.00
R1358:Vmn2r39 UTSW 7 9023688 missense possibly damaging 0.63
R1480:Vmn2r39 UTSW 7 9014956 missense probably damaging 1.00
R4119:Vmn2r39 UTSW 7 9023674 missense probably benign 0.01
R4120:Vmn2r39 UTSW 7 9023674 missense probably benign 0.01
R4720:Vmn2r39 UTSW 7 9023470 critical splice donor site probably null
R4990:Vmn2r39 UTSW 7 9023676 missense probably benign
R5079:Vmn2r39 UTSW 7 9023490 missense probably benign 0.05
R5695:Vmn2r39 UTSW 7 9025151 missense possibly damaging 0.87
R6131:Vmn2r39 UTSW 7 9014964 missense probably damaging 1.00
R6561:Vmn2r39 UTSW 7 9015093 missense probably damaging 1.00
R7108:Vmn2r39 UTSW 7 9023668 missense probably damaging 0.96
R7122:Vmn2r39 UTSW 7 9014762 missense possibly damaging 0.72
Z1176:Vmn2r39 UTSW 7 9015033 missense probably damaging 1.00
Posted On2016-08-02