Incidental Mutation 'IGL03019:Lce1k'
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ID407988
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lce1k
Ensembl Gene ENSMUSG00000095870
Gene Namelate cornified envelope 1K
SynonymsGm7055, Sprrl6
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.132) question?
Stock #IGL03019
Quality Score
Status
Chromosome3
Chromosomal Location92806291-92807891 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to C at 92806779 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Glycine at position 33 (C33G)
Ref Sequence ENSEMBL: ENSMUSP00000137052 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000179917]
Predicted Effect unknown
Transcript: ENSMUST00000179917
AA Change: C33G
SMART Domains Protein: ENSMUSP00000137052
Gene: ENSMUSG00000095870
AA Change: C33G

DomainStartEndE-ValueType
Pfam:LCE 22 62 3e-10 PFAM
Pfam:LCE 59 125 1.9e-12 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 22 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ackr2 T A 9: 121,909,182 Y208N probably benign Het
Agap2 T C 10: 127,091,562 probably benign Het
Arhgap21 A T 2: 20,861,063 I914N probably damaging Het
Brsk1 T C 7: 4,710,497 probably benign Het
Cachd1 A T 4: 100,952,085 T256S probably damaging Het
Ccdc171 G T 4: 83,795,308 G1195W probably damaging Het
Cept1 A G 3: 106,504,641 M339T probably damaging Het
Cir1 T C 2: 73,286,348 K223E unknown Het
Cited2 A T 10: 17,724,162 M73L probably benign Het
Drg2 T C 11: 60,456,595 Y37H probably damaging Het
Drosha T C 15: 12,846,099 L440P probably damaging Het
Dsc1 G A 18: 20,088,364 P685S probably benign Het
Epha1 T A 6: 42,362,752 D639V probably damaging Het
Fam212b G T 3: 105,716,371 M1I probably null Het
Izumo4 A G 10: 80,703,846 probably benign Het
Kcnmb2 A T 3: 32,198,150 R167W probably damaging Het
Map7 C T 10: 20,267,355 P417S unknown Het
Myo18b A G 5: 112,692,397 V2510A probably benign Het
Rubcn A T 16: 32,826,707 V787D probably damaging Het
Spen A T 4: 141,478,916 L800Q unknown Het
Zfp276 C A 8: 123,267,934 T580N probably damaging Het
Zfp354c G T 11: 50,817,194 P60T probably damaging Het
Other mutations in Lce1k
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02733:Lce1k APN 3 92806885 utr 5 prime probably benign
R1990:Lce1k UTSW 3 92806818 missense unknown
R1991:Lce1k UTSW 3 92806818 missense unknown
R1992:Lce1k UTSW 3 92806818 missense unknown
R2024:Lce1k UTSW 3 92806502 missense unknown
R2065:Lce1k UTSW 3 92806857 nonsense probably null
R2361:Lce1k UTSW 3 92806584 missense unknown
R2906:Lce1k UTSW 3 92806575 missense unknown
R4688:Lce1k UTSW 3 92806644 missense unknown
R4902:Lce1k UTSW 3 92806827 missense unknown
R7405:Lce1k UTSW 3 92806874 start codon destroyed probably null
Posted On2016-08-02