Incidental Mutation 'IGL03032:Olfr344'
ID408477
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr344
Ensembl Gene ENSMUSG00000096822
Gene Nameolfactory receptor 344
SynonymsGA_x6K02T2NLDC-33262744-33263673, MOR136-12
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.079) question?
Stock #IGL03032
Quality Score
Status
Chromosome2
Chromosomal Location36566662-36576178 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to A at 36568704 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 35 (Y35*)
Ref Sequence ENSEMBL: ENSMUSP00000151202 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000075474] [ENSMUST00000215879]
Predicted Effect probably null
Transcript: ENSMUST00000075474
AA Change: Y35*
SMART Domains Protein: ENSMUSP00000074919
Gene: ENSMUSG00000096822
AA Change: Y35*

DomainStartEndE-ValueType
Pfam:7tm_4 31 308 5.7e-56 PFAM
Pfam:7tm_1 41 290 2.1e-22 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000215879
AA Change: Y35*
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310003L06Rik A T 5: 87,971,915 Y177F possibly damaging Het
Als2 C A 1: 59,216,030 probably benign Het
Arhgap44 A G 11: 65,024,212 L410P probably damaging Het
Atp13a2 C T 4: 141,000,355 A481V possibly damaging Het
Bod1l C A 5: 41,831,584 L393F probably benign Het
Cflar T A 1: 58,741,020 I258N probably damaging Het
Col24a1 T C 3: 145,538,703 probably null Het
Csmd2 A T 4: 128,519,041 N2542I probably benign Het
Cyp2b9 T C 7: 26,198,600 probably benign Het
Dip2c A T 13: 9,551,778 I258F probably damaging Het
Dock7 A G 4: 98,966,348 S1560P probably benign Het
Drc7 C T 8: 95,076,247 probably benign Het
Gm3667 T A 14: 6,872,191 S203C probably null Het
Gramd2 A G 9: 59,712,127 E190G probably benign Het
Gstm4 T C 3: 108,043,947 D8G probably damaging Het
Heatr5b A T 17: 78,760,499 M1820K probably benign Het
Irs4 A G X: 141,722,798 Y801H unknown Het
Loxhd1 C T 18: 77,286,473 T80I possibly damaging Het
Lrrc40 G A 3: 158,041,665 probably benign Het
Mapk8ip1 T G 2: 92,386,613 K446Q probably damaging Het
Mettl21e C A 1: 44,210,159 probably null Het
Mmp8 T A 9: 7,558,529 probably benign Het
Muc19 A T 15: 91,910,539 noncoding transcript Het
Nipsnap3b T A 4: 53,015,016 V21E possibly damaging Het
Olfr1040 A G 2: 86,146,699 F12L probably damaging Het
Olfr1354 A T 10: 78,917,637 I266F probably benign Het
Parp12 G A 6: 39,087,586 probably null Het
Pramef17 C A 4: 143,993,245 L183F probably damaging Het
Rgsl1 T A 1: 153,826,202 T169S possibly damaging Het
Rnf38 T C 4: 44,152,529 R12G probably damaging Het
Slc9c1 T C 16: 45,543,261 probably benign Het
Slpi T C 2: 164,355,447 probably benign Het
Snx17 G A 5: 31,196,011 V165I probably benign Het
Tnfaip3 A G 10: 19,004,609 V570A probably benign Het
Vmn1r63 A G 7: 5,803,351 M94T probably benign Het
Vmn2r95 A G 17: 18,452,313 I771V probably benign Het
Wiz A G 17: 32,356,558 V868A probably benign Het
Other mutations in Olfr344
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01093:Olfr344 APN 2 36568826 missense probably damaging 1.00
IGL01450:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01452:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01458:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01466:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01470:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01476:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01477:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01478:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01480:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01481:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01487:Olfr344 APN 2 36568742 missense probably damaging 1.00
IGL01522:Olfr344 APN 2 36569221 missense probably benign 0.00
IGL02141:Olfr344 APN 2 36568808 missense probably damaging 1.00
IGL02510:Olfr344 APN 2 36568681 missense possibly damaging 0.87
IGL02896:Olfr344 APN 2 36569205 missense possibly damaging 0.88
R0081:Olfr344 UTSW 2 36568881 nonsense probably null
R0581:Olfr344 UTSW 2 36568822 missense probably damaging 1.00
R0611:Olfr344 UTSW 2 36569556 splice site probably null
R1503:Olfr344 UTSW 2 36568873 missense probably damaging 1.00
R1844:Olfr344 UTSW 2 36568777 missense probably damaging 1.00
R2320:Olfr344 UTSW 2 36568625 missense possibly damaging 0.90
R4088:Olfr344 UTSW 2 36569018 missense probably damaging 1.00
R5243:Olfr344 UTSW 2 36568643 missense probably damaging 1.00
R5747:Olfr344 UTSW 2 36568967 missense probably damaging 0.98
R5948:Olfr344 UTSW 2 36569351 missense probably damaging 1.00
R6115:Olfr344 UTSW 2 36568951 missense probably damaging 1.00
R6158:Olfr344 UTSW 2 36569116 missense probably benign 0.03
R6198:Olfr344 UTSW 2 36568951 missense probably damaging 1.00
R6531:Olfr344 UTSW 2 36569341 missense probably damaging 1.00
R7075:Olfr344 UTSW 2 36569180 missense probably benign 0.01
R7193:Olfr344 UTSW 2 36569236 missense probably benign 0.06
R7329:Olfr344 UTSW 2 36568696 missense probably benign
R7659:Olfr344 UTSW 2 36568625 missense possibly damaging 0.90
R8251:Olfr344 UTSW 2 36569455 missense probably damaging 1.00
R8383:Olfr344 UTSW 2 36569002 missense probably benign 0.08
R8507:Olfr344 UTSW 2 36569431 missense probably damaging 0.98
Posted On2016-08-02