Incidental Mutation 'IGL03051:Ighv7-1'
ID409078
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ighv7-1
Ensembl Gene ENSMUSG00000076665
Gene Nameimmunoglobulin heavy variable 7-1
SynonymsGm16698
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.085) question?
Stock #IGL03051
Quality Score
Status
Chromosome12
Chromosomal Location113896408-113896946 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to T at 113896956 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000100255 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000103474]
Predicted Effect probably benign
Transcript: ENSMUST00000103474
SMART Domains Protein: ENSMUSP00000100255
Gene: ENSMUSG00000076665

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
IGv 36 119 6.1e-35 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aak1 G T 6: 86,987,301 probably benign Het
Abhd14a A T 9: 106,443,929 F76I possibly damaging Het
Acvr1b A G 15: 101,203,078 R374G probably damaging Het
Akap13 T A 7: 75,610,485 C149* probably null Het
Appbp2 A T 11: 85,191,739 D555E possibly damaging Het
Arhgap25 T C 6: 87,495,914 Q87R probably null Het
Baz1b T A 5: 135,217,225 N509K probably benign Het
Ces5a C A 8: 93,528,598 G156C probably damaging Het
Chtf18 G A 17: 25,720,964 R723W probably damaging Het
Clec4e A G 6: 123,289,733 S6P probably benign Het
Dennd4a A G 9: 64,862,414 I468V probably damaging Het
Epb41l4a A T 18: 33,874,772 Y233N probably damaging Het
Fam210b C T 2: 172,352,692 H155Y probably benign Het
Frmd4b A T 6: 97,295,982 C770* probably null Het
Gpa33 A G 1: 166,165,221 H301R probably benign Het
Gpr39 T A 1: 125,677,748 C138S probably damaging Het
Gtf2i T A 5: 134,242,914 K858* probably null Het
Iglv1 T C 16: 19,085,223 T49A possibly damaging Het
Kif17 A C 4: 138,289,254 D416A probably damaging Het
Mib2 T C 4: 155,657,290 T431A probably damaging Het
Mpz G A 1: 171,158,811 R98H probably damaging Het
Naa16 T C 14: 79,369,082 E337G probably benign Het
Odam G A 5: 87,892,476 probably benign Het
Olfr397 T A 11: 73,965,034 L142H probably benign Het
Parp2 T C 14: 50,819,348 probably benign Het
Pcdh7 T G 5: 58,129,073 S1164A probably damaging Het
Pkp4 G T 2: 59,311,762 A470S probably benign Het
Plin4 A T 17: 56,105,417 M538K possibly damaging Het
Prex2 T C 1: 11,142,665 V624A probably damaging Het
Rps6ka5 A C 12: 100,615,991 probably null Het
Simc1 T C 13: 54,526,223 S795P probably benign Het
Slc35b4 A T 6: 34,160,471 probably null Het
Stxbp2 A T 8: 3,641,971 I538F probably benign Het
Syt14 T C 1: 192,933,220 N486S probably benign Het
Trim59 T C 3: 69,036,873 N378S probably benign Het
Wdr17 T A 8: 54,651,314 D908V probably damaging Het
Wdr74 A G 19: 8,739,511 probably benign Het
Wisp1 T A 15: 66,906,550 C73* probably null Het
Other mutations in Ighv7-1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01637:Ighv7-1 APN 12 113896503 missense possibly damaging 0.78
IGL03006:Ighv7-1 APN 12 113896525 missense probably damaging 1.00
IGL03281:Ighv7-1 APN 12 113896951 unclassified probably benign
R3008:Ighv7-1 UTSW 12 113896451 missense probably damaging 1.00
R5754:Ighv7-1 UTSW 12 113896619 missense probably damaging 0.99
R6172:Ighv7-1 UTSW 12 113896563 missense probably damaging 0.99
R6213:Ighv7-1 UTSW 12 113896521 missense probably damaging 0.99
R7324:Ighv7-1 UTSW 12 113896529 missense probably damaging 1.00
R8399:Ighv7-1 UTSW 12 113896912 missense unknown
Posted On2016-08-02