Incidental Mutation 'IGL03059:Prelid3a'
ID409389
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prelid3a
Ensembl Gene ENSMUSG00000024530
Gene NamePRELI domain containing 3A
SynonymsA230074A19Rik, Slmo1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.163) question?
Stock #IGL03059
Quality Score
Status
Chromosome18
Chromosomal Location67464849-67480581 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to A at 67476839 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 112 (Y112*)
Ref Sequence ENSEMBL: ENSMUSP00000025411 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025411]
Predicted Effect probably null
Transcript: ENSMUST00000025411
AA Change: Y112*
SMART Domains Protein: ENSMUSP00000025411
Gene: ENSMUSG00000024530
AA Change: Y112*

DomainStartEndE-ValueType
Pfam:PRELI 15 170 1.7e-52 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahsg T C 16: 22,899,005 V244A possibly damaging Het
Ccdc187 C A 2: 26,294,241 R48M probably null Het
Cnga2 G A X: 72,008,272 R251H probably damaging Het
Cop1 A C 1: 159,306,709 K174Q probably damaging Het
Cul9 T C 17: 46,538,987 D512G probably damaging Het
Flt4 G A 11: 49,642,307 A1140T probably damaging Het
Galnt3 C T 2: 66,093,610 R438H probably damaging Het
Gatm G A 2: 122,609,700 A86V probably damaging Het
Klhl28 C T 12: 64,951,566 A385T probably benign Het
Klhl40 T A 9: 121,778,137 V121E probably damaging Het
L1cam T A X: 73,867,024 H30L probably benign Het
Lss A T 10: 76,532,026 probably benign Het
Mrnip A T 11: 50,199,769 Q253H probably damaging Het
Mroh9 A T 1: 163,024,636 F828Y possibly damaging Het
Mst1 T C 9: 108,084,813 C668R probably damaging Het
Nadk A G 4: 155,586,796 E143G probably benign Het
Nap1l4 C T 7: 143,527,165 probably null Het
Nme8 A G 13: 19,652,244 I254T possibly damaging Het
Olfr1382 A G 11: 49,535,194 Y3C probably benign Het
Olfr295 A G 7: 86,585,571 I99V probably benign Het
Olfr374 T A 8: 72,109,998 L144Q probably damaging Het
Pkd1l2 G A 8: 117,065,745 T436I probably benign Het
Pkd1l3 C T 8: 109,648,367 L1491F probably damaging Het
Plec G T 15: 76,175,768 T3488N probably damaging Het
Plk2 T G 13: 110,399,134 S497A probably benign Het
Polr1a G A 6: 71,936,512 V617I probably benign Het
Rnf113a2 C A 12: 84,417,476 S47R possibly damaging Het
Rtel1 A G 2: 181,350,183 N410D probably benign Het
Ryr3 C T 2: 112,800,047 A2140T probably damaging Het
Slc22a29 A G 19: 8,169,990 L336P probably benign Het
Sphkap T A 1: 83,257,242 Q1621L probably damaging Het
Svs1 A T 6: 48,987,415 Y119F probably benign Het
Tcrg-C1 A T 13: 19,215,902 K123* probably null Het
Ttn T A 2: 76,909,519 S3559C probably benign Het
Ubr4 C T 4: 139,480,676 R4923W probably damaging Het
Vac14 T C 8: 110,710,452 L599P probably damaging Het
Wdr5 T C 2: 27,519,734 probably benign Het
Other mutations in Prelid3a
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02702:Prelid3a APN 18 67473794 missense probably damaging 1.00
R2294:Prelid3a UTSW 18 67472871 missense probably damaging 1.00
R4112:Prelid3a UTSW 18 67472897 missense probably damaging 1.00
R4113:Prelid3a UTSW 18 67472897 missense probably damaging 1.00
R5553:Prelid3a UTSW 18 67477023 missense probably damaging 1.00
R5951:Prelid3a UTSW 18 67464941 missense probably benign
Posted On2016-08-02