Incidental Mutation 'IGL03063:Gm17190'
ID409546
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17190
Ensembl Gene ENSMUSG00000099115
Gene Namepredicted gene 17190
Synonyms
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.488) question?
Stock #IGL03063
Quality Score
Status
Chromosome13
Chromosomal Location96082054-96083231 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) G to A at 96082762 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000152074 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000161263] [ENSMUST00000182289] [ENSMUST00000185178] [ENSMUST00000220449]
Predicted Effect probably benign
Transcript: ENSMUST00000161263
SMART Domains Protein: ENSMUSP00000124473
Gene: ENSMUSG00000051111

DomainStartEndE-ValueType
low complexity region 51 61 N/A INTRINSIC
Pfam:Sugar_tr 117 428 9.1e-31 PFAM
Pfam:MFS_1 154 470 5e-27 PFAM
Pfam:Pentapeptide_4 496 573 4.8e-12 PFAM
Pfam:MFS_1 564 725 1.5e-11 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000182289
SMART Domains Protein: ENSMUSP00000138317
Gene: ENSMUSG00000051111

DomainStartEndE-ValueType
low complexity region 51 61 N/A INTRINSIC
Pfam:Sugar_tr 119 427 2.2e-30 PFAM
Pfam:MFS_1 154 470 5e-27 PFAM
Pfam:Pentapeptide_4 496 571 6.2e-15 PFAM
transmembrane domain 581 603 N/A INTRINSIC
transmembrane domain 610 632 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000184369
Predicted Effect unknown
Transcript: ENSMUST00000185178
AA Change: G202D
SMART Domains Protein: ENSMUSP00000138965
Gene: ENSMUSG00000099115
AA Change: G202D

DomainStartEndE-ValueType
internal_repeat_1 32 57 4.12e-5 PROSPERO
RRM 72 144 5.93e-17 SMART
low complexity region 153 278 N/A INTRINSIC
low complexity region 286 311 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000220449
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc6 C T 7: 46,016,432 V255I probably benign Het
Arfgef2 T C 2: 166,859,782 probably benign Het
Bpifb2 A T 2: 153,889,124 Q205L probably damaging Het
Ccdc30 C T 4: 119,349,767 R386Q possibly damaging Het
Cdk5rap2 T A 4: 70,354,877 probably null Het
Comtd1 A G 14: 21,847,667 probably null Het
Dao T C 5: 114,021,015 C261R probably damaging Het
Dner A G 1: 84,585,338 V187A possibly damaging Het
Dsg3 T C 18: 20,533,368 probably benign Het
Eif3j2 A G 18: 43,477,379 L123P possibly damaging Het
Esf1 G A 2: 140,154,786 probably benign Het
Exo5 G A 4: 120,921,633 T345I possibly damaging Het
Fancl A T 11: 26,387,299 I29F probably damaging Het
Gadl1 C T 9: 115,966,267 H313Y probably damaging Het
Gtf3c1 G T 7: 125,646,503 T1580N possibly damaging Het
Gtf3c6 T A 10: 40,251,159 I66L probably benign Het
Hhla1 A G 15: 65,941,790 I231T probably damaging Het
Hk2 A G 6: 82,739,649 Y273H probably damaging Het
Hk2 A G 6: 82,749,232 I83T probably benign Het
Ifit1 T C 19: 34,648,004 V180A possibly damaging Het
Igkv9-129 A T 6: 67,840,188 D92V probably damaging Het
Lrrc1 A G 9: 77,499,269 F36S probably damaging Het
Man1b1 A G 2: 25,334,404 E102G possibly damaging Het
Myh8 A G 11: 67,288,205 S475G probably benign Het
Olfr593 T A 7: 103,212,634 V247D probably damaging Het
Otud4 T A 8: 79,663,790 M343K probably benign Het
Peg10 A T 6: 4,756,647 probably benign Het
Plet1 T A 9: 50,504,422 N197K probably benign Het
Ppp1r12a C T 10: 108,261,254 R243C probably damaging Het
Serpinb10 A T 1: 107,542,227 K146N possibly damaging Het
Sis A G 3: 72,928,297 F911L probably benign Het
Spon1 G A 7: 114,033,025 V528M possibly damaging Het
Tdrd9 T C 12: 112,044,299 V1100A probably benign Het
Tmtc3 T C 10: 100,447,606 M696V probably benign Het
Triobp A G 15: 78,990,884 E122G probably damaging Het
Wt1 G A 2: 105,170,023 probably null Het
Other mutations in Gm17190
AlleleSourceChrCoordTypePredicted EffectPPH Score
R6603:Gm17190 UTSW 13 96082262 missense possibly damaging 0.81
R7359:Gm17190 UTSW 13 96082462 missense probably damaging 0.98
R7466:Gm17190 UTSW 13 96082779 nonsense probably null
R8166:Gm17190 UTSW 13 96082634 missense unknown
Posted On2016-08-02