Incidental Mutation 'IGL03063:Gm17190'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17190
Ensembl Gene ENSMUSG00000099115
Gene Namepredicted gene 17190
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.488) question?
Stock #IGL03063
Quality Score
Chromosomal Location96082054-96083231 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) G to A at 96082762 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000152074 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000161263] [ENSMUST00000182289] [ENSMUST00000185178] [ENSMUST00000220449]
Predicted Effect probably benign
Transcript: ENSMUST00000161263
SMART Domains Protein: ENSMUSP00000124473
Gene: ENSMUSG00000051111

low complexity region 51 61 N/A INTRINSIC
Pfam:Sugar_tr 117 428 9.1e-31 PFAM
Pfam:MFS_1 154 470 5e-27 PFAM
Pfam:Pentapeptide_4 496 573 4.8e-12 PFAM
Pfam:MFS_1 564 725 1.5e-11 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000182289
SMART Domains Protein: ENSMUSP00000138317
Gene: ENSMUSG00000051111

low complexity region 51 61 N/A INTRINSIC
Pfam:Sugar_tr 119 427 2.2e-30 PFAM
Pfam:MFS_1 154 470 5e-27 PFAM
Pfam:Pentapeptide_4 496 571 6.2e-15 PFAM
transmembrane domain 581 603 N/A INTRINSIC
transmembrane domain 610 632 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000184369
Predicted Effect unknown
Transcript: ENSMUST00000185178
AA Change: G202D
SMART Domains Protein: ENSMUSP00000138965
Gene: ENSMUSG00000099115
AA Change: G202D

internal_repeat_1 32 57 4.12e-5 PROSPERO
RRM 72 144 5.93e-17 SMART
low complexity region 153 278 N/A INTRINSIC
low complexity region 286 311 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000220449
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc6 C T 7: 46,016,432 V255I probably benign Het
Arfgef2 T C 2: 166,859,782 probably benign Het
Bpifb2 A T 2: 153,889,124 Q205L probably damaging Het
Ccdc30 C T 4: 119,349,767 R386Q possibly damaging Het
Cdk5rap2 T A 4: 70,354,877 probably null Het
Comtd1 A G 14: 21,847,667 probably null Het
Dao T C 5: 114,021,015 C261R probably damaging Het
Dner A G 1: 84,585,338 V187A possibly damaging Het
Dsg3 T C 18: 20,533,368 probably benign Het
Eif3j2 A G 18: 43,477,379 L123P possibly damaging Het
Esf1 G A 2: 140,154,786 probably benign Het
Exo5 G A 4: 120,921,633 T345I possibly damaging Het
Fancl A T 11: 26,387,299 I29F probably damaging Het
Gadl1 C T 9: 115,966,267 H313Y probably damaging Het
Gtf3c1 G T 7: 125,646,503 T1580N possibly damaging Het
Gtf3c6 T A 10: 40,251,159 I66L probably benign Het
Hhla1 A G 15: 65,941,790 I231T probably damaging Het
Hk2 A G 6: 82,739,649 Y273H probably damaging Het
Hk2 A G 6: 82,749,232 I83T probably benign Het
Ifit1 T C 19: 34,648,004 V180A possibly damaging Het
Igkv9-129 A T 6: 67,840,188 D92V probably damaging Het
Lrrc1 A G 9: 77,499,269 F36S probably damaging Het
Man1b1 A G 2: 25,334,404 E102G possibly damaging Het
Myh8 A G 11: 67,288,205 S475G probably benign Het
Olfr593 T A 7: 103,212,634 V247D probably damaging Het
Otud4 T A 8: 79,663,790 M343K probably benign Het
Peg10 A T 6: 4,756,647 probably benign Het
Plet1 T A 9: 50,504,422 N197K probably benign Het
Ppp1r12a C T 10: 108,261,254 R243C probably damaging Het
Serpinb10 A T 1: 107,542,227 K146N possibly damaging Het
Sis A G 3: 72,928,297 F911L probably benign Het
Spon1 G A 7: 114,033,025 V528M possibly damaging Het
Tdrd9 T C 12: 112,044,299 V1100A probably benign Het
Tmtc3 T C 10: 100,447,606 M696V probably benign Het
Triobp A G 15: 78,990,884 E122G probably damaging Het
Wt1 G A 2: 105,170,023 probably null Het
Other mutations in Gm17190
AlleleSourceChrCoordTypePredicted EffectPPH Score
R6603:Gm17190 UTSW 13 96082262 missense possibly damaging 0.81
R7359:Gm17190 UTSW 13 96082462 missense probably damaging 0.98
R7466:Gm17190 UTSW 13 96082779 nonsense probably null
R8166:Gm17190 UTSW 13 96082634 missense unknown
Posted On2016-08-02