Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03118:Odam'

409859

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Odam

Ensembl Gene

ENSMUSG00000009580

Gene Name

odontogenic, ameloblast asssociated

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.092) question?

Stock #

IGL03118

Quality Score

Status

Chromosome

Chromosomal Location

87885029-87894174 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 87885754 bp

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 15 (S15P)

Ref Sequence

ENSEMBL: ENSMUSP00000117898 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000113274] [ENSMUST00000129757]

Predicted Effect

unknown
Transcript: ENSMUST00000113274
AA Change: S15P

SMART Domains

Protein: ENSMUSP00000108899
Gene: ENSMUSG00000009580
AA Change: S15P

Domain	Start	End	E-Value	Type
Pfam:ODAM	16	273	1.4e-128	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000129757
AA Change: S15P

SMART Domains

Protein: ENSMUSP00000117898
Gene: ENSMUSG00000009580
AA Change: S15P

Domain	Start	End	E-Value	Type
Pfam:ODAM	16	273	5.1e-132	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca3	G	A	17: 24,400,450	G921S	probably benign	Het
Abca8b	T	C	11: 109,947,181	T1082A	possibly damaging	Het
AF366264	C	T	8: 13,838,096		probably benign	Het
B9d2	T	C	7: 25,681,476		probably null	Het
Bfsp1	T	C	2: 143,827,333	E442G	possibly damaging	Het
Bpifb5	C	T	2: 154,236,753		probably benign	Het
Ccl1	A	G	11: 82,178,070	I47T	probably damaging	Het
Cln3	T	C	7: 126,575,397	I285V	probably null	Het
Cyp4a12b	G	T	4: 115,432,976	R242I	possibly damaging	Het
Dcc	T	C	18: 71,420,273	T771A	probably benign	Het
Erbb4	T	C	1: 68,042,719	D1052G	probably benign	Het
Fcnb	T	C	2: 28,076,618	N301S	probably benign	Het
Gm28043	A	C	17: 29,634,731	E403A	probably damaging	Het
Gria4	A	G	9: 4,793,804		probably benign	Het
Ighv5-12	T	A	12: 113,702,578	M1L	probably benign	Het
Il17rd	A	G	14: 27,093,395		probably null	Het
Kcnn3	T	A	3: 89,667,161	L660Q	probably damaging	Het
Lcor	C	T	19: 41,558,369	P131S	probably damaging	Het
Leng1	T	C	7: 3,665,410	N13S	probably damaging	Het
Loxhd1	T	C	18: 77,380,464	V827A	probably damaging	Het
Mapk13	A	G	17: 28,777,735	Y208C	probably benign	Het
Mybpc3	T	C	2: 91,124,503	V453A	probably damaging	Het
Olfr26	A	T	9: 38,855,230	H56L	probably damaging	Het
Olfr323	A	T	11: 58,625,443	V201D	probably damaging	Het
Pcdhb19	T	C	18: 37,499,565		probably benign	Het
Per2	G	T	1: 91,444,619	Y244*	probably null	Het
Pik3ca	A	T	3: 32,459,935	I857F	probably damaging	Het
Pold1	T	A	7: 44,539,400	I447F	probably benign	Het
Ppm1f	T	A	16: 16,914,078	W131R	probably null	Het
Ppp2r2c	A	G	5: 36,926,316	Y67C	probably damaging	Het
Psmb10	A	T	8: 105,936,900	H155Q	probably damaging	Het
Ptbp3	G	A	4: 59,501,470	A149V	probably benign	Het
Pygb	T	A	2: 150,820,811	V566E	probably benign	Het
Rictor	G	A	15: 6,759,518	R205Q	possibly damaging	Het
Ryr1	T	A	7: 29,015,786	R4638W	unknown	Het
Sept3	G	A	15: 82,284,514		probably null	Het
Serpina3b	A	T	12: 104,131,054	D198V	probably benign	Het
Slc27a6	C	A	18: 58,556,743	H94N	probably benign	Het
Taf2	C	T	15: 55,052,163	V456M	probably damaging	Het
Tbpl2	T	C	2: 24,087,289	E238G	probably benign	Het
Ttn	C	T	2: 76,754,207	V20440I	possibly damaging	Het
Zfp638	T	A	6: 83,935,018		probably benign	Het
Zfp865	T	C	7: 5,034,645		probably benign	Het

Other mutations in Odam

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00970:Odam	APN	5	87886608	splice site	probably benign
IGL01339:Odam	APN	5	87885896	critical splice donor site	probably null
IGL01940:Odam	APN	5	87887333	missense	possibly damaging	0.87
IGL02895:Odam	APN	5	87885864	missense	probably benign	0.32
IGL03051:Odam	APN	5	87892476	splice site	probably benign
BB005:Odam	UTSW	5	87887410	missense	possibly damaging	0.95
BB015:Odam	UTSW	5	87887410	missense	possibly damaging	0.95
R1816:Odam	UTSW	5	87889470	splice site	probably null
R2033:Odam	UTSW	5	87892419	missense	probably benign
R4965:Odam	UTSW	5	87890108	nonsense	probably null
R7257:Odam	UTSW	5	87887545	missense	probably benign	0.14
R7682:Odam	UTSW	5	87892428	missense	possibly damaging	0.71
R7928:Odam	UTSW	5	87887410	missense	possibly damaging	0.95
R8099:Odam	UTSW	5	87892440	missense	possibly damaging	0.52

Posted On

2016-08-02