Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03130:Vmn1r3'

410262

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r3

Ensembl Gene

ENSMUSG00000115466

Gene Name

vomeronasal 1 receptor 3

Synonyms

Gm11778

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.323) question?

Stock #

IGL03130

Quality Score

Status

Chromosome

Chromosomal Location

3184385-3185305 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 3185214 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Phenylalanine at position 31 (Y31F)

Ref Sequence

ENSEMBL: ENSMUSP00000100790 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000105159]

AlphaFold

A2AMT7

Predicted Effect

possibly damaging
Transcript: ENSMUST00000105159
AA Change: Y31F

PolyPhen 2 Score 0.887 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000100790
Gene: ENSMUSG00000115466
AA Change: Y31F

Domain	Start	End	E-Value	Type
Pfam:TAS2R	6	302	1.7e-9	PFAM
Pfam:7tm_1	30	292	5.1e-7	PFAM
Pfam:V1R	34	298	1.2e-35	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abtb3	G	T	10: 85,224,347 (GRCm39)		probably null	Het
Agtpbp1	T	C	13: 59,622,403 (GRCm39)	E941G	possibly damaging	Het
Akap11	A	T	14: 78,747,808 (GRCm39)	Y1526*	probably null	Het
Brd1	T	C	15: 88,572,577 (GRCm39)	I1165V	probably benign	Het
Cdan1	T	C	2: 120,558,393 (GRCm39)	D473G	possibly damaging	Het
Clstn3	G	A	6: 124,436,222 (GRCm39)	L176F	probably damaging	Het
Ctif	T	C	18: 75,654,689 (GRCm39)	N279S	probably benign	Het
Dpy19l3	A	G	7: 35,452,097 (GRCm39)	S16P	probably benign	Het
Ecpas	A	T	4: 58,800,288 (GRCm39)	C1806S	probably benign	Het
Fam151b	T	C	13: 92,586,701 (GRCm39)	Y244C	probably benign	Het
Gbf1	T	C	19: 46,255,787 (GRCm39)	M750T	possibly damaging	Het
Gm11564	T	A	11: 99,705,879 (GRCm39)	T184S	unknown	Het
Gnptab	A	G	10: 88,272,233 (GRCm39)	K958E	possibly damaging	Het
Hibch	T	C	1: 52,924,310 (GRCm39)	S162P	possibly damaging	Het
Itpr1	T	C	6: 108,500,362 (GRCm39)	S2651P	probably benign	Het
LTO1	A	G	7: 144,470,197 (GRCm39)	E42G	probably damaging	Het
Lyrm1	A	G	7: 119,513,403 (GRCm39)	D56G	probably damaging	Het
Manba	T	C	3: 135,256,920 (GRCm39)	Y528H	probably damaging	Het
Npas2	A	C	1: 39,352,109 (GRCm39)	E186D	probably damaging	Het
Or4f61	A	T	2: 111,922,166 (GRCm39)	D293E	probably benign	Het
Or7c19	A	T	8: 85,957,258 (GRCm39)	I45F	possibly damaging	Het
Or7d11	C	A	9: 19,966,668 (GRCm39)	L30F	probably benign	Het
Pcdhb6	T	A	18: 37,468,640 (GRCm39)	Y520*	probably null	Het
Plekhm1	C	T	11: 103,268,207 (GRCm39)	R588H	probably benign	Het
Psg23	A	T	7: 18,344,341 (GRCm39)	H371Q	probably benign	Het
Ptpn12	T	C	5: 21,207,610 (GRCm39)		probably benign	Het
Rela	T	C	19: 5,689,909 (GRCm39)	C120R	probably damaging	Het
Rps6kc1	T	A	1: 190,532,008 (GRCm39)	I665F	probably damaging	Het
Spg21	A	G	9: 65,380,990 (GRCm39)	Q99R	probably benign	Het
St14	A	G	9: 31,008,367 (GRCm39)		probably null	Het
Sult1c2	A	T	17: 54,137,099 (GRCm39)	N274K	probably benign	Het
Syk	T	C	13: 52,776,768 (GRCm39)	V256A	probably benign	Het
Tcte1	A	G	17: 45,844,222 (GRCm39)	D66G	probably damaging	Het
Tgm4	C	T	9: 122,885,580 (GRCm39)	T374M	probably damaging	Het
Tns4	T	C	11: 98,959,095 (GRCm39)	H668R	probably damaging	Het
Tsn	C	T	1: 118,232,999 (GRCm39)	A102T	possibly damaging	Het
Uvssa	T	A	5: 33,549,189 (GRCm39)	S350T	possibly damaging	Het
Vmn2r114	A	T	17: 23,515,970 (GRCm39)		probably benign	Het
Vmn2r27	T	C	6: 124,169,276 (GRCm39)	D618G	possibly damaging	Het
Vmn2r91	T	A	17: 18,330,373 (GRCm39)		probably benign	Het
Vti1a	T	C	19: 55,380,279 (GRCm39)	Y143H	probably damaging	Het
Zfand4	T	A	6: 116,250,620 (GRCm39)	Y17N	probably damaging	Het
Zfp729a	T	C	13: 67,767,761 (GRCm39)		probably null	Het
Zfp827	A	G	8: 79,787,586 (GRCm39)	T251A	probably damaging	Het

Other mutations in Vmn1r3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
PIT4131001:Vmn1r3	UTSW	4	3,184,774 (GRCm39)	missense	probably benign	0.02
PIT4131001:Vmn1r3	UTSW	4	3,184,691 (GRCm39)	missense	probably damaging	1.00
PIT4142001:Vmn1r3	UTSW	4	3,184,774 (GRCm39)	missense	probably benign	0.02
PIT4142001:Vmn1r3	UTSW	4	3,184,691 (GRCm39)	missense	probably damaging	1.00
R0972:Vmn1r3	UTSW	4	3,185,125 (GRCm39)	missense	probably damaging	1.00
R1423:Vmn1r3	UTSW	4	3,185,231 (GRCm39)	missense	probably damaging	1.00
R3902:Vmn1r3	UTSW	4	3,185,241 (GRCm39)	missense	probably benign	0.41
R4999:Vmn1r3	UTSW	4	3,185,009 (GRCm39)	nonsense	probably null
R6091:Vmn1r3	UTSW	4	3,184,684 (GRCm39)	missense	probably damaging	0.97
R6140:Vmn1r3	UTSW	4	3,185,031 (GRCm39)	missense	probably damaging	0.97
R6188:Vmn1r3	UTSW	4	3,185,017 (GRCm39)	missense	probably damaging	1.00
R6299:Vmn1r3	UTSW	4	3,185,098 (GRCm39)	missense	possibly damaging	0.95
R6303:Vmn1r3	UTSW	4	3,184,975 (GRCm39)	missense	probably damaging	1.00
R6304:Vmn1r3	UTSW	4	3,184,975 (GRCm39)	missense	probably damaging	1.00
R6317:Vmn1r3	UTSW	4	3,184,993 (GRCm39)	missense	probably benign	0.39
R6430:Vmn1r3	UTSW	4	3,184,971 (GRCm39)	missense	probably benign
R6633:Vmn1r3	UTSW	4	3,184,971 (GRCm39)	missense	probably benign
R8919:Vmn1r3	UTSW	4	3,184,863 (GRCm39)	missense	probably benign	0.03
R9320:Vmn1r3	UTSW	4	3,185,284 (GRCm39)	missense	probably benign	0.00
R9357:Vmn1r3	UTSW	4	3,185,149 (GRCm39)	missense	probably damaging	1.00
Z1177:Vmn1r3	UTSW	4	3,185,304 (GRCm39)	start codon destroyed	probably null	0.60

Posted On

2016-08-02