Incidental Mutation 'IGL03133:Vmn1r5'
ID410396
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r5
Ensembl Gene ENSMUSG00000090346
Gene Namevomeronasal 1 receptor 5
SynonymsV1rc19
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.053) question?
Stock #IGL03133
Quality Score
Status
Chromosome6
Chromosomal Location56970273-56988390 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 56985615 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Serine at position 92 (C92S)
Ref Sequence ENSEMBL: ENSMUSP00000154081 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164307] [ENSMUST00000226130] [ENSMUST00000228276]
Predicted Effect probably benign
Transcript: ENSMUST00000164307
AA Change: C92S

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000131092
Gene: ENSMUSG00000090346
AA Change: C92S

DomainStartEndE-ValueType
Pfam:V1R 28 293 9.7e-53 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226130
AA Change: C92S

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
Predicted Effect probably benign
Transcript: ENSMUST00000228276
AA Change: C92S

PolyPhen 2 Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adarb1 T C 10: 77,325,896 probably benign Het
Ano5 C T 7: 51,576,512 R505* probably null Het
Asphd1 A G 7: 126,948,280 C284R possibly damaging Het
Cep192 T A 18: 67,810,105 W158R probably benign Het
Ces2h T A 8: 105,016,779 D188E probably damaging Het
Dab1 G A 4: 104,727,580 V306I probably benign Het
Dcc A G 18: 71,262,955 probably benign Het
Dennd6b T A 15: 89,188,523 probably null Het
Dmwd T A 7: 19,076,637 V123D probably damaging Het
Eno1 A G 4: 150,245,344 probably benign Het
Fat2 G A 11: 55,286,043 T1542I probably benign Het
Fcrl1 T C 3: 87,389,392 S274P probably benign Het
Gmpr T C 13: 45,517,018 V72A probably benign Het
Kank2 T C 9: 21,795,641 E27G probably null Het
Mtor G T 4: 148,484,319 A1099S probably benign Het
Ofcc1 T C 13: 40,072,768 I763V probably benign Het
Olfr1023 G T 2: 85,887,134 E111D probably damaging Het
Olfr1065 A G 2: 86,445,658 I108T probably damaging Het
Olfr487 G T 7: 108,212,387 S47R possibly damaging Het
Olfr870 T A 9: 20,170,713 N286I probably damaging Het
Piwil1 C A 5: 128,742,029 H201N probably benign Het
Slc26a7 C T 4: 14,532,576 V433M possibly damaging Het
Spata31d1c T C 13: 65,034,985 Y114H probably benign Het
Stx7 A T 10: 24,185,038 N221I probably damaging Het
Tbc1d31 A T 15: 57,942,459 probably benign Het
Ubxn7 T G 16: 32,381,781 L393R probably damaging Het
Vit A T 17: 78,566,071 M59L probably benign Het
Other mutations in Vmn1r5
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01674:Vmn1r5 APN 6 56985926 missense probably damaging 0.98
IGL02027:Vmn1r5 APN 6 56985655 missense probably damaging 0.97
IGL03412:Vmn1r5 APN 6 56985933 missense possibly damaging 0.90
R0316:Vmn1r5 UTSW 6 56985799 missense probably benign 0.27
R0378:Vmn1r5 UTSW 6 56985585 missense probably benign 0.00
R0946:Vmn1r5 UTSW 6 56986165 missense possibly damaging 0.64
R1511:Vmn1r5 UTSW 6 56985786 missense probably benign 0.02
R1553:Vmn1r5 UTSW 6 56985498 missense probably benign 0.00
R1823:Vmn1r5 UTSW 6 56985595 missense probably damaging 0.98
R3980:Vmn1r5 UTSW 6 56985651 missense probably damaging 1.00
R4473:Vmn1r5 UTSW 6 56985648 missense probably benign 0.01
R4742:Vmn1r5 UTSW 6 56986251 nonsense probably null
R5321:Vmn1r5 UTSW 6 56985607 missense probably damaging 1.00
R5364:Vmn1r5 UTSW 6 56985598 missense probably damaging 0.98
R6102:Vmn1r5 UTSW 6 56986114 missense probably damaging 0.96
R6581:Vmn1r5 UTSW 6 56985381 missense probably benign
R6885:Vmn1r5 UTSW 6 56986057 missense possibly damaging 0.89
R7297:Vmn1r5 UTSW 6 56986219 missense possibly damaging 0.94
R8063:Vmn1r5 UTSW 6 56985598 missense probably damaging 0.98
Z1176:Vmn1r5 UTSW 6 56985948 missense possibly damaging 0.75
Posted On2016-08-02