Incidental Mutation 'IGL03133:Vmn1r5'
| ID |
410396 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r5
|
| Ensembl Gene |
ENSMUSG00000090346 |
| Gene Name |
vomeronasal 1 receptor 5 |
| Synonyms |
V1rc19 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.055)
|
| Stock # |
IGL03133
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
56947320-56963335 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 56962600 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 92
(C92S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154081
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000164307]
[ENSMUST00000226130]
[ENSMUST00000228276]
|
| AlphaFold |
B2RQT2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164307
AA Change: C92S
PolyPhen 2
Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000131092
Gene: ENSMUSG00000090346
AA Change: C92S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
28 |
293 |
9.7e-53 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226130
AA Change: C92S
PolyPhen 2
Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228276
AA Change: C92S
PolyPhen 2
Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 27 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adarb1 |
T |
C |
10: 77,161,730 (GRCm39) |
|
probably benign |
Het |
| Ano5 |
C |
T |
7: 51,226,260 (GRCm39) |
R505* |
probably null |
Het |
| Asphd1 |
A |
G |
7: 126,547,452 (GRCm39) |
C284R |
possibly damaging |
Het |
| Cep192 |
T |
A |
18: 67,943,176 (GRCm39) |
W158R |
probably benign |
Het |
| Ces2h |
T |
A |
8: 105,743,411 (GRCm39) |
D188E |
probably damaging |
Het |
| Dab1 |
G |
A |
4: 104,584,777 (GRCm39) |
V306I |
probably benign |
Het |
| Dcc |
A |
G |
18: 71,396,026 (GRCm39) |
|
probably benign |
Het |
| Dennd6b |
T |
A |
15: 89,072,726 (GRCm39) |
|
probably null |
Het |
| Dmwd |
T |
A |
7: 18,810,562 (GRCm39) |
V123D |
probably damaging |
Het |
| Eno1 |
A |
G |
4: 150,329,801 (GRCm39) |
|
probably benign |
Het |
| Fat2 |
G |
A |
11: 55,176,869 (GRCm39) |
T1542I |
probably benign |
Het |
| Fcrl1 |
T |
C |
3: 87,296,699 (GRCm39) |
S274P |
probably benign |
Het |
| Gmpr |
T |
C |
13: 45,670,494 (GRCm39) |
V72A |
probably benign |
Het |
| Kank2 |
T |
C |
9: 21,706,937 (GRCm39) |
E27G |
probably null |
Het |
| Mtor |
G |
T |
4: 148,568,776 (GRCm39) |
A1099S |
probably benign |
Het |
| Ofcc1 |
T |
C |
13: 40,226,244 (GRCm39) |
I763V |
probably benign |
Het |
| Or5m10 |
G |
T |
2: 85,717,478 (GRCm39) |
E111D |
probably damaging |
Het |
| Or5p63 |
G |
T |
7: 107,811,594 (GRCm39) |
S47R |
possibly damaging |
Het |
| Or8b12i |
T |
A |
9: 20,082,009 (GRCm39) |
N286I |
probably damaging |
Het |
| Or8k27 |
A |
G |
2: 86,276,002 (GRCm39) |
I108T |
probably damaging |
Het |
| Piwil1 |
C |
A |
5: 128,819,093 (GRCm39) |
H201N |
probably benign |
Het |
| Slc26a7 |
C |
T |
4: 14,532,576 (GRCm39) |
V433M |
possibly damaging |
Het |
| Spata31d1c |
T |
C |
13: 65,182,799 (GRCm39) |
Y114H |
probably benign |
Het |
| Stx7 |
A |
T |
10: 24,060,936 (GRCm39) |
N221I |
probably damaging |
Het |
| Tbc1d31 |
A |
T |
15: 57,805,855 (GRCm39) |
|
probably benign |
Het |
| Ubxn7 |
T |
G |
16: 32,200,599 (GRCm39) |
L393R |
probably damaging |
Het |
| Vit |
A |
T |
17: 78,873,500 (GRCm39) |
M59L |
probably benign |
Het |
|
| Other mutations in Vmn1r5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01674:Vmn1r5
|
APN |
6 |
56,962,911 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02027:Vmn1r5
|
APN |
6 |
56,962,640 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03412:Vmn1r5
|
APN |
6 |
56,962,918 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0316:Vmn1r5
|
UTSW |
6 |
56,962,784 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0378:Vmn1r5
|
UTSW |
6 |
56,962,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0946:Vmn1r5
|
UTSW |
6 |
56,963,150 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1511:Vmn1r5
|
UTSW |
6 |
56,962,771 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1553:Vmn1r5
|
UTSW |
6 |
56,962,483 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1823:Vmn1r5
|
UTSW |
6 |
56,962,580 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3980:Vmn1r5
|
UTSW |
6 |
56,962,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4473:Vmn1r5
|
UTSW |
6 |
56,962,633 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4742:Vmn1r5
|
UTSW |
6 |
56,963,236 (GRCm39) |
nonsense |
probably null |
|
|
R5321:Vmn1r5
|
UTSW |
6 |
56,962,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5364:Vmn1r5
|
UTSW |
6 |
56,962,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6102:Vmn1r5
|
UTSW |
6 |
56,963,099 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6581:Vmn1r5
|
UTSW |
6 |
56,962,366 (GRCm39) |
missense |
probably benign |
|
|
R6885:Vmn1r5
|
UTSW |
6 |
56,963,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7297:Vmn1r5
|
UTSW |
6 |
56,963,204 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8063:Vmn1r5
|
UTSW |
6 |
56,962,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8766:Vmn1r5
|
UTSW |
6 |
56,963,100 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R8968:Vmn1r5
|
UTSW |
6 |
56,963,182 (GRCm39) |
nonsense |
probably null |
|
|
R9440:Vmn1r5
|
UTSW |
6 |
56,962,415 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9460:Vmn1r5
|
UTSW |
6 |
56,962,829 (GRCm39) |
missense |
|
|
|
Z1176:Vmn1r5
|
UTSW |
6 |
56,962,933 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
| Posted On |
2016-08-02 |
Incidental Mutation