Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03136:Zfp790'

410542

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp790

Ensembl Gene

ENSMUSG00000011427

Gene Name

zinc finger protein 790

Synonyms

6330581L23Rik

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.057) question?

Stock #

IGL03136

Quality Score

Status

Chromosome

Chromosomal Location

29816114-29831005 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 29829895 bp

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Stop codon at position 668 (Y668*)

Ref Sequence

ENSEMBL: ENSMUSP00000136932 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032796] [ENSMUST00000108223] [ENSMUST00000178162]

Predicted Effect

probably null
Transcript: ENSMUST00000032796
AA Change: Y668*

SMART Domains

Protein: ENSMUSP00000032796
Gene: ENSMUSG00000011427
AA Change: Y668*

Domain	Start	End	E-Value	Type
KRAB	5	65	3e-27	SMART
ZnF_C2H2	224	246	2.95e-3	SMART
ZnF_C2H2	252	274	2.53e-2	SMART
ZnF_C2H2	280	302	5.5e-3	SMART
ZnF_C2H2	308	330	2.75e-3	SMART
ZnF_C2H2	336	358	2.12e-4	SMART
ZnF_C2H2	364	386	1.03e-2	SMART
Pfam:zf-C2H2_6	391	403	2.4e-1	PFAM
ZnF_C2H2	448	470	9.56e1	SMART
ZnF_C2H2	476	498	7.26e-3	SMART
ZnF_C2H2	504	526	2.57e-3	SMART
ZnF_C2H2	532	554	6.42e-4	SMART
ZnF_C2H2	640	662	1.12e-3	SMART
ZnF_C2H2	668	690	2.12e-4	SMART
ZnF_C2H2	696	718	1.98e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000108223

SMART Domains

Protein: ENSMUSP00000103858
Gene: ENSMUSG00000050855

Domain	Start	End	E-Value	Type
KRAB	6	67	2.42e-22	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000178162
AA Change: Y668*

SMART Domains

Protein: ENSMUSP00000136932
Gene: ENSMUSG00000011427
AA Change: Y668*

Domain	Start	End	E-Value	Type
KRAB	5	65	3e-27	SMART
ZnF_C2H2	224	246	2.95e-3	SMART
ZnF_C2H2	252	274	2.53e-2	SMART
ZnF_C2H2	280	302	5.5e-3	SMART
ZnF_C2H2	308	330	2.75e-3	SMART
ZnF_C2H2	336	358	2.12e-4	SMART
ZnF_C2H2	364	386	1.03e-2	SMART
ZnF_C2H2	448	470	9.56e1	SMART
ZnF_C2H2	476	498	7.26e-3	SMART
ZnF_C2H2	504	526	2.57e-3	SMART
ZnF_C2H2	532	554	6.42e-4	SMART
ZnF_C2H2	640	662	1.12e-3	SMART
ZnF_C2H2	668	690	2.12e-4	SMART
ZnF_C2H2	696	718	1.98e-4	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
5730522E02Rik	A	G	11: 25,769,122	L7S	unknown	Het
Abr	C	T	11: 76,425,295	W571*	probably null	Het
Adam18	A	T	8: 24,641,836	C420S	probably damaging	Het
Akap5	G	T	12: 76,329,875	E694*	probably null	Het
Bbs1	T	C	19: 4,890,991	K565R	probably benign	Het
Brix1	A	G	15: 10,478,766	F189S	probably damaging	Het
Cnot4	C	A	6: 35,051,241	R480L	probably damaging	Het
Ctu2	A	G	8: 122,479,201		probably benign	Het
Dhcr7	A	G	7: 143,847,366	H422R	probably damaging	Het
Dock1	A	G	7: 135,168,389	M1793V	probably benign	Het
Dock7	A	G	4: 99,003,791	F853L	probably damaging	Het
Fkbp15	G	A	4: 62,340,229		probably benign	Het
Ftsj3	C	T	11: 106,253,813	D117N	probably damaging	Het
Gphn	A	G	12: 78,481,333	I142V	possibly damaging	Het
Hsd3b1	G	A	3: 98,852,985	A230V	probably damaging	Het
Hydin	G	A	8: 110,418,524	A836T	probably benign	Het
Ift52	G	T	2: 163,025,334	E71*	probably null	Het
Ms4a14	T	C	19: 11,304,411	D261G	possibly damaging	Het
Nid1	G	A	13: 13,500,499	V935I	probably benign	Het
Nrap	T	C	19: 56,342,255	K1008E	possibly damaging	Het
Nup210	A	C	6: 91,028,861	V1340G	probably benign	Het
Olfr1442	T	A	19: 12,674,967	I254N	probably damaging	Het
Olfr169	A	T	16: 19,566,353	F177I	probably damaging	Het
Olfr974	T	C	9: 39,943,036	Y259H	probably damaging	Het
Pcdhb15	C	A	18: 37,475,014	T433N	probably damaging	Het
Pdcd6ip	T	A	9: 113,691,499	N139I	probably damaging	Het
Pgbd1	A	G	13: 21,433,439	V80A	possibly damaging	Het
Pigw	A	G	11: 84,877,777	I242T	probably benign	Het
Prtg	T	G	9: 72,856,985	V580G	possibly damaging	Het
Ptpn13	T	A	5: 103,543,463	N1065K	possibly damaging	Het
Qrich1	G	A	9: 108,544,918	R577H	probably damaging	Het
Ryr3	G	A	2: 112,675,974		probably benign	Het
Selenoi	T	C	5: 30,257,727	Y197H	probably damaging	Het
Slc47a2	A	G	11: 61,310,765	C343R	probably benign	Het
Smurf2	A	T	11: 106,831,048	D527E	probably benign	Het
Spam1	C	T	6: 24,797,011		probably benign	Het
Stkld1	T	C	2: 26,951,423	V460A	probably benign	Het
Tgoln1	G	A	6: 72,614,113	R339W	probably damaging	Het
Tprg	T	C	16: 25,412,762		probably benign	Het
Treml1	T	G	17: 48,364,851		probably benign	Het
Ttc39b	A	T	4: 83,237,280	V497E	probably damaging	Het
Vmn1r223	A	G	13: 23,249,763	T176A	possibly damaging	Het
Vmn2r75	A	T	7: 86,148,703	I634N	possibly damaging	Het
Vps13c	A	G	9: 67,950,310	E2608G	probably damaging	Het
Zfp575	A	G	7: 24,585,956	C87R	probably damaging	Het

Other mutations in Zfp790

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00229:Zfp790	APN	7	29828563	missense	probably benign	0.32
IGL00979:Zfp790	APN	7	29829609	missense	probably benign	0.00
IGL02286:Zfp790	APN	7	29829735	missense	possibly damaging	0.53
R0021:Zfp790	UTSW	7	29825688	unclassified	probably benign
R0077:Zfp790	UTSW	7	29824875	missense	probably damaging	0.98
R1477:Zfp790	UTSW	7	29823100	start gained	probably benign
R1572:Zfp790	UTSW	7	29828139	missense	probably benign	0.33
R2015:Zfp790	UTSW	7	29828861	missense	probably benign	0.29
R4941:Zfp790	UTSW	7	29829491	missense	possibly damaging	0.83
R5019:Zfp790	UTSW	7	29829767	missense	probably benign	0.00
R5159:Zfp790	UTSW	7	29829767	missense	probably benign	0.00
R5160:Zfp790	UTSW	7	29829767	missense	probably benign	0.00
R5722:Zfp790	UTSW	7	29830089	nonsense	probably null
R5954:Zfp790	UTSW	7	29829504	missense	probably damaging	1.00
R6025:Zfp790	UTSW	7	29829545	missense	possibly damaging	0.71
R6312:Zfp790	UTSW	7	29828222	missense	probably damaging	1.00
R7392:Zfp790	UTSW	7	29828625	missense	possibly damaging	0.52
R7623:Zfp790	UTSW	7	29825705	nonsense	probably null
R8036:Zfp790	UTSW	7	29828921	missense	possibly damaging	0.92
R8175:Zfp790	UTSW	7	29829780	missense	possibly damaging	0.96

Posted On

2016-08-02