Incidental Mutation 'IGL03140:Vmn1r205'
| ID |
410662 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r205
|
| Ensembl Gene |
ENSMUSG00000100296 |
| Gene Name |
vomeronasal 1 receptor 205 |
| Synonyms |
V1rh8 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.164)
|
| Stock # |
IGL03140
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
22776150-22777100 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 22776746 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 119
(I119V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139977
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000185475]
|
| AlphaFold |
Q8R276 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000185475
AA Change: I119V
PolyPhen 2
Score 0.783 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000139977
Gene: ENSMUSG00000100296
AA Change: I119V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
24 |
307 |
5.5e-36 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 21 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ahnak |
G |
A |
19: 8,982,576 (GRCm39) |
|
probably benign |
Het |
| Cd48 |
T |
C |
1: 171,523,451 (GRCm39) |
V98A |
probably damaging |
Het |
| Chd9 |
A |
T |
8: 91,768,856 (GRCm39) |
R2485S |
possibly damaging |
Het |
| Clec4a2 |
T |
C |
6: 123,117,735 (GRCm39) |
|
probably benign |
Het |
| Ddx21 |
A |
G |
10: 62,429,850 (GRCm39) |
L298S |
probably damaging |
Het |
| Efl1 |
A |
G |
7: 82,342,089 (GRCm39) |
E499G |
probably benign |
Het |
| Fry |
A |
G |
5: 150,419,166 (GRCm39) |
N2870S |
probably damaging |
Het |
| Ints8 |
G |
A |
4: 11,235,565 (GRCm39) |
P355S |
probably damaging |
Het |
| Kmo |
T |
A |
1: 175,476,786 (GRCm39) |
V200D |
probably damaging |
Het |
| Ldlrad4 |
A |
G |
18: 68,387,585 (GRCm39) |
D299G |
probably damaging |
Het |
| Mus81 |
T |
C |
19: 5,533,984 (GRCm39) |
T416A |
probably damaging |
Het |
| Nlrp6 |
T |
C |
7: 140,507,400 (GRCm39) |
S889P |
probably benign |
Het |
| Nlrp9c |
T |
A |
7: 26,079,914 (GRCm39) |
D704V |
probably benign |
Het |
| Olfml2a |
A |
G |
2: 38,837,303 (GRCm39) |
K149E |
probably damaging |
Het |
| Ovgp1 |
A |
G |
3: 105,887,222 (GRCm39) |
D206G |
probably damaging |
Het |
| Pcdhb3 |
T |
G |
18: 37,434,272 (GRCm39) |
H79Q |
probably benign |
Het |
| Pira13 |
T |
C |
7: 3,826,247 (GRCm39) |
N249D |
probably benign |
Het |
| Rnf19b |
T |
A |
4: 128,977,889 (GRCm39) |
V701D |
probably benign |
Het |
| Setd2 |
T |
C |
9: 110,444,020 (GRCm39) |
|
probably null |
Het |
| Ubr3 |
A |
G |
2: 69,800,533 (GRCm39) |
Y952C |
probably damaging |
Het |
| Zfhx4 |
T |
G |
3: 5,307,585 (GRCm39) |
D270E |
probably damaging |
Het |
|
| Other mutations in Vmn1r205 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01329:Vmn1r205
|
APN |
13 |
22,776,273 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02148:Vmn1r205
|
APN |
13 |
22,776,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02608:Vmn1r205
|
APN |
13 |
22,776,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0831:Vmn1r205
|
UTSW |
13 |
22,776,586 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1418:Vmn1r205
|
UTSW |
13 |
22,777,049 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1873:Vmn1r205
|
UTSW |
13 |
22,776,223 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2358:Vmn1r205
|
UTSW |
13 |
22,776,566 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2434:Vmn1r205
|
UTSW |
13 |
22,776,524 (GRCm39) |
missense |
probably benign |
0.37 |
|
R3105:Vmn1r205
|
UTSW |
13 |
22,777,109 (GRCm39) |
unclassified |
probably benign |
|
|
R3725:Vmn1r205
|
UTSW |
13 |
22,776,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4758:Vmn1r205
|
UTSW |
13 |
22,777,016 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4851:Vmn1r205
|
UTSW |
13 |
22,777,074 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5642:Vmn1r205
|
UTSW |
13 |
22,776,206 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6447:Vmn1r205
|
UTSW |
13 |
22,776,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7453:Vmn1r205
|
UTSW |
13 |
22,776,931 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8177:Vmn1r205
|
UTSW |
13 |
22,776,415 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8813:Vmn1r205
|
UTSW |
13 |
22,776,424 (GRCm39) |
missense |
probably benign |
0.36 |
|
| Posted On |
2016-08-02 |
Incidental Mutation