Incidental Mutation 'IGL03155:Vmn1r222'
ID411208
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r222
Ensembl Gene ENSMUSG00000061022
Gene Namevomeronasal 1 receptor 222
SynonymsV1rh16
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.116) question?
Stock #IGL03155
Quality Score
Status
Chromosome13
Chromosomal Location23232066-23233119 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 23232693 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Tryptophan at position 117 (R117W)
Ref Sequence ENSEMBL: ENSMUSP00000076365 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000077116]
Predicted Effect probably damaging
Transcript: ENSMUST00000077116
AA Change: R117W

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000076365
Gene: ENSMUSG00000061022
AA Change: R117W

DomainStartEndE-ValueType
Pfam:V1R 32 297 3.6e-39 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000225143
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 49 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adra1d C T 2: 131,546,081 R518H probably benign Het
Akr7a5 T A 4: 139,314,526 C190* probably null Het
Cct2 A T 10: 117,060,671 L209Q probably damaging Het
Chordc1 T A 9: 18,304,320 S123T possibly damaging Het
Crtap T C 9: 114,380,049 D309G possibly damaging Het
Csf2 T C 11: 54,247,671 T115A possibly damaging Het
Dgkb T A 12: 38,139,459 I287N probably damaging Het
Dyrk1b G A 7: 28,182,687 D98N probably benign Het
Eif4g1 T C 16: 20,692,417 S1550P probably damaging Het
Fam83e A G 7: 45,727,075 E404G possibly damaging Het
Fryl G A 5: 73,076,695 P1496S probably benign Het
Fsip1 A T 2: 118,251,739 N71K probably benign Het
Gm5092 A T 17: 21,094,708 noncoding transcript Het
Gnb1l T A 16: 18,540,532 probably null Het
Got1l1 T C 8: 27,199,332 Y233C probably damaging Het
Katnbl1 T A 2: 112,409,232 probably null Het
Kcnn2 A G 18: 45,685,315 E493G probably damaging Het
Kif26b C T 1: 178,874,128 R691W probably damaging Het
Lrp2 A T 2: 69,455,452 probably benign Het
Mast3 A G 8: 70,789,217 S107P probably damaging Het
Mrc1 A G 2: 14,331,101 N1433D probably benign Het
Mycbp2 G A 14: 103,155,453 S3114L probably benign Het
Naip6 T A 13: 100,316,424 H43L possibly damaging Het
Nin A T 12: 70,031,770 C1681S probably damaging Het
Nnmt C T 9: 48,592,052 V225M probably damaging Het
Olfr1233 A T 2: 89,339,966 M112K probably damaging Het
Olfr694 A T 7: 106,689,239 M164K probably damaging Het
Phf21a T G 2: 92,320,266 V64G probably damaging Het
Ptprd A T 4: 76,066,219 S800R possibly damaging Het
Scarf2 C T 16: 17,807,549 P823S probably benign Het
Scn5a T C 9: 119,512,182 T1212A possibly damaging Het
Slc38a10 C T 11: 120,105,119 V1043I probably damaging Het
Stxbp5 A T 10: 9,816,290 L370Q probably null Het
Tas1r2 T C 4: 139,669,156 V602A possibly damaging Het
Tatdn1 T C 15: 58,916,196 probably benign Het
Tdrd6 A T 17: 43,625,507 L1550Q probably damaging Het
Tet3 G T 6: 83,368,383 R1556S probably damaging Het
Tnpo2 T A 8: 85,045,080 I249N probably benign Het
Tnxb G T 17: 34,713,595 V2263F probably damaging Het
Trim75 C T 8: 64,983,340 V153M possibly damaging Het
Ttc21a T A 9: 119,943,976 probably null Het
Tuft1 T A 3: 94,634,514 I61L possibly damaging Het
Usp43 T C 11: 67,876,489 D680G probably damaging Het
Vac14 A G 8: 110,636,343 I274V possibly damaging Het
Vmn1r83 T C 7: 12,321,690 M147V probably benign Het
Vmn2r43 T A 7: 8,255,069 I382L possibly damaging Het
Vmn2r63 C T 7: 42,903,454 V793I probably damaging Het
Vopp1 A G 6: 57,762,507 Y19H possibly damaging Het
Yeats2 T C 16: 20,229,573 probably null Het
Other mutations in Vmn1r222
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01539:Vmn1r222 APN 13 23232889 missense probably benign 0.45
IGL01960:Vmn1r222 APN 13 23232145 missense probably benign 0.00
IGL02082:Vmn1r222 APN 13 23232329 missense probably damaging 1.00
IGL02616:Vmn1r222 APN 13 23232141 missense possibly damaging 0.73
IGL03333:Vmn1r222 APN 13 23233007 missense probably benign 0.18
IGL03391:Vmn1r222 APN 13 23232462 missense possibly damaging 0.94
R0137:Vmn1r222 UTSW 13 23232804 missense probably damaging 1.00
R1584:Vmn1r222 UTSW 13 23232762 missense probably damaging 1.00
R2352:Vmn1r222 UTSW 13 23232513 missense probably benign 0.35
R3079:Vmn1r222 UTSW 13 23232461 missense possibly damaging 0.75
R3080:Vmn1r222 UTSW 13 23232461 missense possibly damaging 0.75
R3963:Vmn1r222 UTSW 13 23232932 missense probably benign 0.01
R4448:Vmn1r222 UTSW 13 23232293 missense probably benign 0.11
R4448:Vmn1r222 UTSW 13 23232660 missense probably damaging 0.99
R4979:Vmn1r222 UTSW 13 23232432 missense possibly damaging 0.78
R5054:Vmn1r222 UTSW 13 23232731 missense probably damaging 0.98
R5182:Vmn1r222 UTSW 13 23232497 missense probably damaging 1.00
R5230:Vmn1r222 UTSW 13 23233002 missense probably benign
R5462:Vmn1r222 UTSW 13 23232875 missense probably benign 0.05
R5611:Vmn1r222 UTSW 13 23232573 missense probably damaging 1.00
R5677:Vmn1r222 UTSW 13 23232780 missense probably damaging 1.00
R6298:Vmn1r222 UTSW 13 23232795 missense probably benign 0.15
R6655:Vmn1r222 UTSW 13 23232716 missense probably damaging 1.00
R6748:Vmn1r222 UTSW 13 23232947 missense probably benign 0.00
R6912:Vmn1r222 UTSW 13 23232204 missense probably benign 0.44
R7663:Vmn1r222 UTSW 13 23232431 missense possibly damaging 0.78
R7764:Vmn1r222 UTSW 13 23232359 missense probably damaging 1.00
Z1177:Vmn1r222 UTSW 13 23232460 missense possibly damaging 0.94
Posted On2016-08-02