Incidental Mutation 'IGL03159:Cyp2j7'
ID411359
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cyp2j7
Ensembl Gene ENSMUSG00000081362
Gene Namecytochrome P450, family 2, subfamily j, polypeptide 7
SynonymsCyp2j7-ps, OTTMUSG00000007941
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL03159
Quality Score
Status
Chromosome4
Chromosomal Location96195197-96236659 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 96227512 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000134331 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000162514]
Predicted Effect probably benign
Transcript: ENSMUST00000162514
SMART Domains Protein: ENSMUSP00000134331
Gene: ENSMUSG00000081362

DomainStartEndE-ValueType
transmembrane domain 10 32 N/A INTRINSIC
Pfam:p450 44 499 3.7e-130 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adamts6 T A 13: 104,444,215 M812K probably damaging Het
Ctnnal1 G A 4: 56,844,599 R122W probably benign Het
Defa29 A G 8: 21,326,962 V5A possibly damaging Het
Defb22 A G 2: 152,490,075 F13L probably benign Het
Gm884 T A 11: 103,604,502 probably benign Het
Gmds C A 13: 31,819,951 D362Y probably damaging Het
Gtf2h1 T C 7: 46,806,743 V179A possibly damaging Het
Idh3b T A 2: 130,284,401 N6I probably benign Het
Kcnk7 T C 19: 5,706,088 L114P probably damaging Het
Lama1 G A 17: 67,804,536 G2261R probably damaging Het
Mfsd3 A G 15: 76,702,901 T285A probably benign Het
Olfr996 A G 2: 85,579,940 R234G probably damaging Het
Prrc2b T C 2: 32,194,486 M321T probably damaging Het
Sf3b1 A T 1: 55,012,213 N185K probably benign Het
Smo A G 6: 29,758,505 R550G probably benign Het
Tbc1d31 T G 15: 57,920,048 probably null Het
Uck1 G A 2: 32,258,322 R161C probably benign Het
Vmn1r202 G A 13: 22,501,470 T259I probably benign Het
Vmn2r72 A T 7: 85,754,954 F10I probably benign Het
Other mutations in Cyp2j7
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00426:Cyp2j7 APN 4 96227512 splice site probably benign
IGL00426:Cyp2j7 APN 4 96227513 splice site probably null
IGL01505:Cyp2j7 APN 4 96227680 critical splice acceptor site probably null
IGL02100:Cyp2j7 APN 4 96236556 missense probably damaging 0.99
IGL02183:Cyp2j7 APN 4 96230147 splice site probably benign
IGL02596:Cyp2j7 APN 4 96215422 missense possibly damaging 0.56
IGL02661:Cyp2j7 APN 4 96236650 missense probably benign
IGL02723:Cyp2j7 APN 4 96230129 missense probably benign 0.33
IGL03053:Cyp2j7 APN 4 96230037 missense probably benign 0.00
IGL03168:Cyp2j7 APN 4 96230037 missense probably benign 0.00
IGL03174:Cyp2j7 APN 4 96195370 nonsense probably null
PIT4449001:Cyp2j7 UTSW 4 96215338 missense probably damaging 0.96
R0016:Cyp2j7 UTSW 4 96202147 missense probably damaging 0.99
R0016:Cyp2j7 UTSW 4 96202147 missense probably damaging 0.99
R0392:Cyp2j7 UTSW 4 96199434 missense probably damaging 1.00
R1447:Cyp2j7 UTSW 4 96195293 missense possibly damaging 0.90
R1778:Cyp2j7 UTSW 4 96199390 missense probably damaging 1.00
R1876:Cyp2j7 UTSW 4 96217419 missense probably benign 0.01
R4105:Cyp2j7 UTSW 4 96199450 missense possibly damaging 0.84
R4106:Cyp2j7 UTSW 4 96199450 missense possibly damaging 0.84
R4107:Cyp2j7 UTSW 4 96199450 missense possibly damaging 0.84
R4108:Cyp2j7 UTSW 4 96199450 missense possibly damaging 0.84
R4438:Cyp2j7 UTSW 4 96217409 missense probably benign 0.01
R4660:Cyp2j7 UTSW 4 96195342 missense probably benign 0.29
R6193:Cyp2j7 UTSW 4 96195203 missense probably damaging 1.00
R6380:Cyp2j7 UTSW 4 96229974 critical splice donor site probably null
R6427:Cyp2j7 UTSW 4 96227667 missense probably damaging 0.96
R6624:Cyp2j7 UTSW 4 96227618 missense probably damaging 0.99
R7196:Cyp2j7 UTSW 4 96215414 missense probably benign 0.03
R7417:Cyp2j7 UTSW 4 96201988 critical splice donor site probably null
R7780:Cyp2j7 UTSW 4 96230019 missense probably benign 0.00
R8062:Cyp2j7 UTSW 4 96215350 missense probably null 1.00
R8097:Cyp2j7 UTSW 4 96215410 missense possibly damaging 0.95
R8201:Cyp2j7 UTSW 4 96195327 missense probably damaging 1.00
R8279:Cyp2j7 UTSW 4 96228559 critical splice donor site probably null
Posted On2016-08-02