Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03162:Gpr150'

411487

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gpr150

Ensembl Gene

ENSMUSG00000045509

Gene Name

G protein-coupled receptor 150

Synonyms

PGR11, C030001A19Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.089) question?

Stock #

IGL03162

Quality Score

Status

Chromosome

Chromosomal Location

76202970-76205115 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to A at 76204950 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000113274 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000056130] [ENSMUST00000120573]

AlphaFold

Q8BL07

Predicted Effect

probably benign
Transcript: ENSMUST00000056130

SMART Domains

Protein: ENSMUSP00000049592
Gene: ENSMUSG00000045509

Domain	Start	End	E-Value	Type
low complexity region	37	50	N/A	INTRINSIC
Pfam:7tm_1	66	345	2.7e-22	PFAM
low complexity region	353	370	N/A	INTRINSIC
low complexity region	387	401	N/A	INTRINSIC
low complexity region	410	420	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000120573

SMART Domains

Protein: ENSMUSP00000113274
Gene: ENSMUSG00000021592

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:Sulfatase	35	371	6e-49	PFAM
low complexity region	381	392	N/A	INTRINSIC
low complexity region	537	555	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A1bg	T	A	15: 60,791,581 (GRCm39)	D92V	probably damaging	Het
Acsl3	T	C	1: 78,676,887 (GRCm39)		probably null	Het
Adam5	T	C	8: 25,271,620 (GRCm39)	T596A	probably benign	Het
Adh6a	T	A	3: 138,034,880 (GRCm39)	Y336*	probably null	Het
Ak3	A	T	19: 29,000,236 (GRCm39)	V225D	possibly damaging	Het
Aldh1a7	T	A	19: 20,685,645 (GRCm39)	I302F	probably benign	Het
Amdhd1	T	C	10: 93,367,337 (GRCm39)		probably null	Het
Arhgef18	G	A	8: 3,491,301 (GRCm39)		probably null	Het
Caap1	A	T	4: 94,389,261 (GRCm39)		probably benign	Het
Cdhr4	G	A	9: 107,875,210 (GRCm39)	G70D	probably damaging	Het
Celsr3	T	C	9: 108,719,757 (GRCm39)	F2445S	probably damaging	Het
Cenpc1	A	G	5: 86,185,764 (GRCm39)	V249A	possibly damaging	Het
Clca3a2	C	A	3: 144,512,177 (GRCm39)	V80F	probably damaging	Het
Col6a1	T	A	10: 76,553,885 (GRCm39)		probably benign	Het
Commd10	T	A	18: 47,220,117 (GRCm39)	L198Q	probably damaging	Het
Cyp2d40	A	G	15: 82,644,243 (GRCm39)	L294P	unknown	Het
E2f6	T	A	12: 16,868,909 (GRCm39)	D77E	probably benign	Het
Elf5	T	A	2: 103,260,751 (GRCm39)	H38Q	possibly damaging	Het
Entrep1	T	G	19: 23,965,824 (GRCm39)	H225P	probably damaging	Het
Fcrl6	A	G	1: 172,425,820 (GRCm39)	V227A	probably damaging	Het
Fhip2b	G	T	14: 70,824,994 (GRCm39)	D447E	probably damaging	Het
Gabarapl2	T	A	8: 112,669,168 (GRCm39)	V42D	probably benign	Het
Gm3543	A	G	14: 41,802,022 (GRCm39)	I154T	possibly damaging	Het
Gstp3	A	G	19: 4,109,255 (GRCm39)		probably benign	Het
Gzmm	C	T	10: 79,528,790 (GRCm39)	T64I	probably damaging	Het
Hs3st1	T	A	5: 39,771,792 (GRCm39)	K284*	probably null	Het
Ints7	A	G	1: 191,353,524 (GRCm39)		probably benign	Het
Itih2	A	T	2: 10,131,055 (GRCm39)	I94N	probably damaging	Het
Kif26b	A	G	1: 178,744,497 (GRCm39)	N1531S	probably benign	Het
Kif27	T	C	13: 58,459,021 (GRCm39)	S937G	probably benign	Het
Klhl2	A	G	8: 65,207,426 (GRCm39)	V311A	probably damaging	Het
Klrb1b	T	A	6: 128,795,892 (GRCm39)	Q109L	probably null	Het
Lrig2	A	G	3: 104,371,613 (GRCm39)	F697L	probably damaging	Het
Lrrc66	T	C	5: 73,764,725 (GRCm39)	R773G	probably benign	Het
Mrgpra2b	C	T	7: 47,113,815 (GRCm39)	V306I	probably benign	Het
Nipbl	T	C	15: 8,368,463 (GRCm39)	H1127R	probably benign	Het
Nr3c2	A	T	8: 77,944,213 (GRCm39)	D816V	probably damaging	Het
Ntmt2	T	A	1: 163,530,783 (GRCm39)	I219L	probably damaging	Het
Or10a3	T	C	7: 108,480,811 (GRCm39)	M1V	probably null	Het
Or5w19	A	C	2: 87,698,484 (GRCm39)	M50L	probably benign	Het
Pdxdc1	A	G	16: 13,675,281 (GRCm39)	L350P	probably damaging	Het
Pkd1l2	G	A	8: 117,792,484 (GRCm39)	T436I	probably benign	Het
Pnpla7	T	C	2: 24,905,301 (GRCm39)		probably benign	Het
Ppan	T	G	9: 20,802,608 (GRCm39)	L283R	probably damaging	Het
Rbfox3	A	C	11: 118,387,257 (GRCm39)	S286A	probably benign	Het
Rbl2	A	G	8: 91,812,330 (GRCm39)	T273A	probably benign	Het
Recql4	G	T	15: 76,590,296 (GRCm39)		probably null	Het
Slc22a26	T	A	19: 7,779,466 (GRCm39)	M117L	probably benign	Het
Sult2a2	T	A	7: 13,468,822 (GRCm39)	I96K	probably damaging	Het
Tcf15	G	A	2: 151,990,626 (GRCm39)	R175H	probably benign	Het
Uggt1	A	T	1: 36,247,037 (GRCm39)	V320D	probably damaging	Het
Vmn2r102	A	G	17: 19,914,286 (GRCm39)	N617S	probably damaging	Het
Vpreb3	A	G	10: 75,785,133 (GRCm39)	Y77C	probably damaging	Het
Zbbx	A	T	3: 74,978,930 (GRCm39)		probably benign	Het
Zfand6	A	T	7: 84,283,185 (GRCm39)	S57R	probably benign	Het
Zmym2	A	G	14: 57,151,500 (GRCm39)	I462V	probably benign	Het

Other mutations in Gpr150

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01350:Gpr150	APN	13	76,204,542 (GRCm39)	missense	probably benign
IGL01759:Gpr150	APN	13	76,203,784 (GRCm39)	missense	possibly damaging	0.94
R1103:Gpr150	UTSW	13	76,203,712 (GRCm39)	missense	probably damaging	1.00
R3885:Gpr150	UTSW	13	76,204,657 (GRCm39)	missense	probably damaging	0.98
R4472:Gpr150	UTSW	13	76,204,273 (GRCm39)	missense	probably benign	0.15
R5838:Gpr150	UTSW	13	76,204,045 (GRCm39)	missense	probably benign	0.01
R5861:Gpr150	UTSW	13	76,204,192 (GRCm39)	missense	possibly damaging	0.48
R6170:Gpr150	UTSW	13	76,204,676 (GRCm39)	missense	probably damaging	0.97
R7190:Gpr150	UTSW	13	76,203,992 (GRCm39)	missense	probably benign	0.10
R7248:Gpr150	UTSW	13	76,204,126 (GRCm39)	missense	probably benign	0.01
R7257:Gpr150	UTSW	13	76,204,585 (GRCm39)	missense	probably benign	0.00
R7665:Gpr150	UTSW	13	76,204,093 (GRCm39)	missense	probably damaging	1.00
R7821:Gpr150	UTSW	13	76,204,511 (GRCm39)	missense	probably benign	0.19
R8712:Gpr150	UTSW	13	76,204,642 (GRCm39)	missense	probably damaging	1.00
R8904:Gpr150	UTSW	13	76,204,528 (GRCm39)	nonsense	probably null
R9308:Gpr150	UTSW	13	76,203,701 (GRCm39)	missense	probably damaging	1.00
R9334:Gpr150	UTSW	13	76,204,103 (GRCm39)	missense	probably benign
R9799:Gpr150	UTSW	13	76,204,636 (GRCm39)	missense	possibly damaging	0.70
Z1177:Gpr150	UTSW	13	76,204,269 (GRCm39)	nonsense	probably null

Posted On

2016-08-02