Incidental Mutation 'IGL03165:Cnnm3'
ID411616
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cnnm3
Ensembl Gene ENSMUSG00000001138
Gene Namecyclin M3
SynonymsAcdp3
Accession Numbers

Genbank: NM_053186, NM_001039551; MGI: 2151055

Is this an essential gene? Probably non essential (E-score: 0.110) question?
Stock #IGL03165
Quality Score
Status
Chromosome1
Chromosomal Location36511867-36528237 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) T to G at 36525232 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000141394 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000001166] [ENSMUST00000097776] [ENSMUST00000191849] [ENSMUST00000193083]
Predicted Effect probably benign
Transcript: ENSMUST00000001166
SMART Domains Protein: ENSMUSP00000001166
Gene: ENSMUSG00000001138

DomainStartEndE-ValueType
signal peptide 1 17 N/A INTRINSIC
low complexity region 25 35 N/A INTRINSIC
low complexity region 87 104 N/A INTRINSIC
low complexity region 128 140 N/A INTRINSIC
Pfam:DUF21 142 295 3.2e-10 PFAM
Blast:CBS 329 379 9e-12 BLAST
Pfam:CBS 388 452 6.4e-6 PFAM
Blast:cNMP 527 668 2e-38 BLAST
Predicted Effect probably benign
Transcript: ENSMUST00000097776
SMART Domains Protein: ENSMUSP00000095383
Gene: ENSMUSG00000001138

DomainStartEndE-ValueType
signal peptide 1 17 N/A INTRINSIC
low complexity region 25 35 N/A INTRINSIC
low complexity region 87 104 N/A INTRINSIC
low complexity region 128 140 N/A INTRINSIC
Pfam:DUF21 142 300 1e-19 PFAM
Blast:CBS 329 379 9e-12 BLAST
Pfam:CBS 388 452 5.1e-6 PFAM
Blast:cNMP 527 668 1e-37 BLAST
Predicted Effect noncoding transcript
Transcript: ENSMUST00000135100
Predicted Effect noncoding transcript
Transcript: ENSMUST00000154225
Predicted Effect probably benign
Transcript: ENSMUST00000191849
SMART Domains Protein: ENSMUSP00000142202
Gene: ENSMUSG00000109510

DomainStartEndE-ValueType
Blast:ANK 1 26 9e-9 BLAST
ANK 30 59 1.12e-3 SMART
ANK 63 92 1.4e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000192037
Predicted Effect probably benign
Transcript: ENSMUST00000193083
SMART Domains Protein: ENSMUSP00000141394
Gene: ENSMUSG00000067653

DomainStartEndE-ValueType
Blast:ANK 1 26 1e-8 BLAST
ANK 30 59 6.9e-6 SMART
ANK 63 92 8.9e-7 SMART
ANK 96 125 5.7e-7 SMART
ANK 129 158 4.6e-6 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrb3 T C 1: 25,094,394 I334V probably benign Het
Axdnd1 T A 1: 156,378,389 Y519F probably benign Het
C4b A G 17: 34,739,955 F500S probably benign Het
Cacng2 A T 15: 77,995,663 I153N possibly damaging Het
Ces1d T A 8: 93,189,519 H160L probably benign Het
Ctnna3 A G 10: 64,945,941 T728A probably damaging Het
Cyp2g1 G A 7: 26,809,776 V92M possibly damaging Het
Dock2 C A 11: 34,687,533 V35F probably damaging Het
Eif2a C A 3: 58,548,628 Y349* probably null Het
Erp44 C T 4: 48,236,872 probably null Het
Flg2 C T 3: 93,214,611 H1363Y unknown Het
Flnc G T 6: 29,449,378 G1425W probably damaging Het
Frem3 A G 8: 80,612,529 N484D probably benign Het
Fstl3 A G 10: 79,779,965 D95G probably benign Het
Gldc A G 19: 30,098,993 S1018P possibly damaging Het
Gstk1 T G 6: 42,249,434 I159S probably benign Het
Herc2 A G 7: 56,191,912 E3513G probably damaging Het
Hpca A T 4: 129,118,590 I51N probably damaging Het
Hsd17b7 C T 1: 169,953,080 E320K probably damaging Het
Igkv4-74 T C 6: 69,185,305 probably benign Het
Kdm7a C A 6: 39,170,914 probably benign Het
Olfr1040 A C 2: 86,146,068 L222R possibly damaging Het
Olfr382 A T 11: 73,516,884 L105* probably null Het
Olfr619 T C 7: 103,604,011 I119T probably damaging Het
Pa2g4 A T 10: 128,559,060 probably null Het
Pdlim3 T A 8: 45,918,998 L360Q possibly damaging Het
Pkd1l2 G A 8: 117,065,745 T436I probably benign Het
Polk T A 13: 96,516,688 Q68L probably benign Het
Ppfia2 T G 10: 106,767,487 L195R probably damaging Het
Ranbp1 A T 16: 18,247,281 probably benign Het
Rbm12b1 A G 4: 12,145,845 R606G possibly damaging Het
Ryr1 A G 7: 29,105,040 V488A probably benign Het
Sall2 A T 14: 52,314,168 D521E probably damaging Het
Sntg1 A T 1: 8,445,104 C402S probably damaging Het
Spg7 T C 8: 123,080,812 probably null Het
Stk31 G A 6: 49,445,264 E750K probably damaging Het
Tlr2 A G 3: 83,837,948 I276T probably benign Het
Trav12-2 A T 14: 53,616,749 H60L probably benign Het
Urb1 A G 16: 90,780,304 L775S probably damaging Het
Utp14b A G 1: 78,664,520 D45G probably damaging Het
Other mutations in Cnnm3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01310:Cnnm3 APN 1 36512875 missense probably benign 0.12
IGL02679:Cnnm3 APN 1 36520158 missense probably benign 0.01
IGL02700:Cnnm3 APN 1 36513108 missense probably damaging 1.00
R0003:Cnnm3 UTSW 1 36524043 missense probably benign 0.02
R0358:Cnnm3 UTSW 1 36521222 missense probably damaging 0.98
R1129:Cnnm3 UTSW 1 36513016 missense probably damaging 1.00
R1772:Cnnm3 UTSW 1 36518957 missense probably damaging 1.00
R2929:Cnnm3 UTSW 1 36524059 missense possibly damaging 0.55
R3153:Cnnm3 UTSW 1 36521222 missense probably damaging 0.98
R3154:Cnnm3 UTSW 1 36521222 missense probably damaging 0.98
R5376:Cnnm3 UTSW 1 36520678 missense probably damaging 1.00
R5810:Cnnm3 UTSW 1 36525199 missense probably benign 0.02
R6389:Cnnm3 UTSW 1 36520522 missense probably damaging 0.99
R8288:Cnnm3 UTSW 1 36511993 missense possibly damaging 0.93
X0064:Cnnm3 UTSW 1 36512980 missense probably damaging 1.00
Z1177:Cnnm3 UTSW 1 36513033 missense possibly damaging 0.96
Posted On2016-08-02