Incidental Mutation 'IGL03170:Xkr9'
ID411801
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Xkr9
Ensembl Gene ENSMUSG00000067813
Gene NameX-linked Kx blood group related 9
SynonymsLOC381246
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.076) question?
Stock #IGL03170
Quality Score
Status
Chromosome1
Chromosomal Location13668771-13701723 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 13700812 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Threonine at position 184 (I184T)
Ref Sequence ENSEMBL: ENSMUSP00000085900 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088542]
Predicted Effect possibly damaging
Transcript: ENSMUST00000088542
AA Change: I184T

PolyPhen 2 Score 0.716 (Sensitivity: 0.86; Specificity: 0.92)
SMART Domains Protein: ENSMUSP00000085900
Gene: ENSMUSG00000067813
AA Change: I184T

DomainStartEndE-ValueType
Pfam:XK-related 9 346 2.8e-87 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310035C23Rik C T 1: 105,735,955 T943I probably damaging Het
Cand2 A G 6: 115,797,900 D1023G probably damaging Het
Cyp2c54 A G 19: 40,072,365 probably null Het
Cyp4f37 C T 17: 32,625,119 probably benign Het
Cyr61 C A 3: 145,649,759 A12S probably benign Het
Entpd2 T C 2: 25,399,481 F325S probably damaging Het
Flnb T C 14: 7,818,261 I37T possibly damaging Het
Gm7030 C T 17: 36,128,713 G125E probably damaging Het
Gm7534 C T 4: 134,193,034 V607I possibly damaging Het
Gtpbp10 A G 5: 5,555,355 V116A probably benign Het
Lrp1b T A 2: 40,697,444 N164I unknown Het
Nle1 T A 11: 82,904,270 T312S probably benign Het
Olfr509 T C 7: 108,646,100 I159V probably benign Het
Pim1 T A 17: 29,491,178 L12Q possibly damaging Het
Plb1 G T 5: 32,284,902 C246F probably damaging Het
Ppp4r4 T C 12: 103,590,774 probably benign Het
Prl6a1 T A 13: 27,315,423 V63D possibly damaging Het
Ptprz1 G A 6: 22,959,767 A88T probably benign Het
Ranbp3l A T 15: 9,000,787 E31V probably damaging Het
Rgs9 G A 11: 109,259,855 T209I probably benign Het
Smg8 A G 11: 87,086,608 V49A probably damaging Het
Smim6 A T 11: 115,913,488 T34S possibly damaging Het
Snw1 T G 12: 87,472,252 T4P probably benign Het
Sod2 C A 17: 13,008,370 H70Q probably benign Het
Tro A G X: 150,655,560 S34P probably benign Het
Tshr T A 12: 91,537,869 M527K probably damaging Het
Uggt1 A C 1: 36,163,261 V1085G probably damaging Het
Vmn1r21 A G 6: 57,843,862 V199A probably damaging Het
Zfp369 T C 13: 65,294,410 S273P probably damaging Het
Other mutations in Xkr9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01990:Xkr9 APN 1 13700979 missense probably benign 0.00
IGL02090:Xkr9 APN 1 13701376 missense probably damaging 1.00
IGL02405:Xkr9 APN 1 13672773 splice site probably benign
IGL02523:Xkr9 APN 1 13684250 missense probably benign 0.01
IGL02792:Xkr9 APN 1 13700803 missense probably damaging 1.00
IGL02820:Xkr9 APN 1 13700949 missense probably benign
IGL02821:Xkr9 APN 1 13672575 missense probably damaging 1.00
IGL03222:Xkr9 APN 1 13701281 nonsense probably null
R0044:Xkr9 UTSW 1 13684062 nonsense probably null
R0044:Xkr9 UTSW 1 13684062 nonsense probably null
R0595:Xkr9 UTSW 1 13700784 missense probably benign 0.02
R1337:Xkr9 UTSW 1 13701124 missense possibly damaging 0.94
R1670:Xkr9 UTSW 1 13700943 missense probably damaging 0.97
R5007:Xkr9 UTSW 1 13701163 missense probably damaging 0.98
R6133:Xkr9 UTSW 1 13684135 missense probably benign 0.01
R6302:Xkr9 UTSW 1 13672502 missense probably damaging 1.00
X0025:Xkr9 UTSW 1 13672634 missense probably benign 0.43
Posted On2016-08-02