Incidental Mutation 'IGL03174:Gm17067'
ID411961
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm17067
Ensembl Gene ENSMUSG00000091594
Gene Namepredicted gene 17067
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.075) question?
Stock #IGL03174
Quality Score
Status
Chromosome7
Chromosomal Location42705469-42727017 bp(-) (GRCm38)
Type of Mutationcritical splice donor site (1 bp from exon)
DNA Base Change (assembly) C to A at 42710676 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000128086 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000166837] [ENSMUST00000180131]
Predicted Effect probably null
Transcript: ENSMUST00000166837
SMART Domains Protein: ENSMUSP00000128086
Gene: ENSMUSG00000091594

DomainStartEndE-ValueType
KRAB 4 66 4.19e-17 SMART
ZnF_C2H2 131 153 1.28e-3 SMART
ZnF_C2H2 159 181 9.73e-4 SMART
ZnF_C2H2 187 209 1.03e-2 SMART
ZnF_C2H2 215 237 1.28e-3 SMART
ZnF_C2H2 243 265 1.38e-3 SMART
ZnF_C2H2 271 293 1.04e-3 SMART
ZnF_C2H2 299 321 8.47e-4 SMART
ZnF_C2H2 327 349 1.13e-4 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000180131
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700022I11Rik T C 4: 42,970,975 Y67H probably benign Het
Abcb1b T C 5: 8,827,752 L703P probably benign Het
Abi3bp A G 16: 56,614,747 K602R possibly damaging Het
Ank2 T C 3: 126,940,095 D622G probably damaging Het
Bpifb1 T A 2: 154,213,049 L287Q probably damaging Het
Brd8 T C 18: 34,604,909 E774G probably damaging Het
C87977 C T 4: 144,208,430 S247N probably benign Het
Cnot1 A G 8: 95,761,355 S558P probably damaging Het
Col15a1 T C 4: 47,282,666 I781T probably damaging Het
Cyp2j7 T A 4: 96,195,370 R448* probably null Het
Dgkb A T 12: 38,216,054 I511F possibly damaging Het
Fam221b T C 4: 43,666,542 E23G probably benign Het
Grin3a T A 4: 49,771,107 D555V probably damaging Het
Hid1 T C 11: 115,360,389 Y107C probably damaging Het
Kcnd2 A G 6: 21,216,516 D73G possibly damaging Het
Kit A G 5: 75,607,113 D52G probably benign Het
Llgl1 G T 11: 60,706,210 R189L probably benign Het
Lrp2 T A 2: 69,466,265 D3315V probably damaging Het
Map3k8 A G 18: 4,349,247 S24P probably damaging Het
Nckap5 A G 1: 125,981,646 L1616P probably damaging Het
Nrcam A G 12: 44,576,006 probably benign Het
Olfr1475 A G 19: 13,480,069 M43T probably benign Het
Olfr715b A T 7: 107,106,270 M197K probably benign Het
Polr1a G A 6: 71,977,347 R1595H possibly damaging Het
Rusc1 T C 3: 89,091,770 D235G probably damaging Het
Serpinb6e A T 13: 33,836,480 I215N probably damaging Het
Sfrp4 A T 13: 19,632,207 Q137L probably benign Het
Vmn2r2 C T 3: 64,117,123 W679* probably null Het
Vps8 T A 16: 21,466,463 L398H probably damaging Het
Zfp709 A T 8: 71,889,026 T99S probably benign Het
Other mutations in Gm17067
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0016:Gm17067 UTSW 7 42708622 missense probably benign 0.05
R0445:Gm17067 UTSW 7 42708622 missense probably benign 0.00
R3911:Gm17067 UTSW 7 42710680 missense possibly damaging 0.51
R4380:Gm17067 UTSW 7 42708038 missense probably benign 0.00
R5502:Gm17067 UTSW 7 42708419 missense probably damaging 0.97
R5557:Gm17067 UTSW 7 42708521 missense probably damaging 1.00
R5602:Gm17067 UTSW 7 42708415 missense probably damaging 0.98
R5875:Gm17067 UTSW 7 42708046 missense probably benign 0.00
R6016:Gm17067 UTSW 7 42708230 missense probably benign 0.24
R6029:Gm17067 UTSW 7 42708130 missense probably benign 0.06
R6360:Gm17067 UTSW 7 42708482 missense probably benign
R6562:Gm17067 UTSW 7 42708729 missense probably damaging 1.00
R6892:Gm17067 UTSW 7 42710675 critical splice donor site probably null
Z1177:Gm17067 UTSW 7 42708298 missense probably benign 0.05
Posted On2016-08-02