Incidental Mutation 'IGL03176:Cd164l2'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cd164l2
Ensembl Gene ENSMUSG00000028865
Gene NameCD164 sialomucin-like 2
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.132) question?
Stock #IGL03176
Quality Score
Chromosomal Location133212131-133224555 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 133224254 bp
Amino Acid Change Isoleucine to Threonine at position 172 (I172T)
Ref Sequence ENSEMBL: ENSMUSP00000101530 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000105910]
Predicted Effect possibly damaging
Transcript: ENSMUST00000105910
AA Change: I172T

PolyPhen 2 Score 0.793 (Sensitivity: 0.85; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000101530
Gene: ENSMUSG00000028865
AA Change: I172T

signal peptide 1 29 N/A INTRINSIC
Pfam:MGC-24 53 125 1.8e-17 PFAM
Pfam:MGC-24 113 171 7.4e-26 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000126929
Predicted Effect noncoding transcript
Transcript: ENSMUST00000134713
Predicted Effect noncoding transcript
Transcript: ENSMUST00000150744
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218338
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218998
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam23 C A 1: 63,563,416 P579Q probably damaging Het
Adam6a A G 12: 113,546,202 T732A probably benign Het
Ahnak T A 19: 9,008,166 N2271K possibly damaging Het
Ahnak T C 19: 9,002,449 S366P probably damaging Het
Akr1a1 A G 4: 116,639,075 L213S probably damaging Het
Ammecr1l T A 18: 31,772,049 D114E possibly damaging Het
Casq2 G T 3: 102,126,654 V167L possibly damaging Het
Clec4g C T 8: 3,718,441 V97M possibly damaging Het
Dnah8 T A 17: 30,694,037 N1068K probably benign Het
Epyc A G 10: 97,649,700 M1V probably null Het
Eya3 A G 4: 132,711,922 E437G possibly damaging Het
Fbln1 C T 15: 85,244,306 T568I possibly damaging Het
Fcrl1 A T 3: 87,391,257 N353I probably damaging Het
Gm10272 A T 10: 77,706,633 H3L probably null Het
Gm15130 A G 2: 111,148,501 S32P unknown Het
Gm20379 C A 13: 92,306,021 probably benign Het
Igf2r A T 17: 12,716,672 Y644N probably damaging Het
Krtap4-9 T C 11: 99,785,280 probably benign Het
Man2c1 A G 9: 57,140,746 N739D probably benign Het
Mcm5 C T 8: 75,109,853 T49M possibly damaging Het
Otof C T 5: 30,405,176 probably null Het
Ptgr2 C T 12: 84,307,894 T283I probably damaging Het
Rhox4c G T X: 37,480,528 G15V probably benign Het
Rnd1 A T 15: 98,670,688 L203H probably damaging Het
Rnf186 A G 4: 138,967,920 N257S probably benign Het
Rsf1 T C 7: 97,679,150 probably benign Het
Ryr2 G A 13: 11,742,023 Q1582* probably null Het
Sntg2 G A 12: 30,267,023 probably benign Het
Spata31d1c A G 13: 65,037,011 D789G probably benign Het
Strc A C 2: 121,372,180 L1168R probably damaging Het
Tmtc3 A T 10: 100,466,131 S319T possibly damaging Het
Vmn1r88 A T 7: 13,177,852 D45V probably damaging Het
Vps13d A T 4: 145,074,963 F3531I probably benign Het
Other mutations in Cd164l2
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1679:Cd164l2 UTSW 4 133221499 missense probably benign 0.00
R4484:Cd164l2 UTSW 4 133223675 missense probably damaging 1.00
R5215:Cd164l2 UTSW 4 133221478 missense unknown
R5556:Cd164l2 UTSW 4 133223705 missense probably damaging 0.98
R6257:Cd164l2 UTSW 4 133221034 missense unknown
Posted On2016-08-02