Incidental Mutation 'IGL03176:Vmn1r88'
ID412011
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r88
Ensembl Gene ENSMUSG00000095902
Gene Namevomeronasal 1 receptor, 88
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.059) question?
Stock #IGL03176
Quality Score
Status
Chromosome7
Chromosomal Location13177719-13178669 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 13177852 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Valine at position 45 (D45V)
Ref Sequence ENSEMBL: ENSMUSP00000128946 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000171783]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000122190
Predicted Effect probably damaging
Transcript: ENSMUST00000171783
AA Change: D45V

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000128946
Gene: ENSMUSG00000095902
AA Change: D45V

DomainStartEndE-ValueType
Pfam:TAS2R 1 306 2e-14 PFAM
Pfam:V1R 35 301 1.4e-30 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam23 C A 1: 63,563,416 P579Q probably damaging Het
Adam6a A G 12: 113,546,202 T732A probably benign Het
Ahnak T A 19: 9,008,166 N2271K possibly damaging Het
Ahnak T C 19: 9,002,449 S366P probably damaging Het
Akr1a1 A G 4: 116,639,075 L213S probably damaging Het
Ammecr1l T A 18: 31,772,049 D114E possibly damaging Het
Casq2 G T 3: 102,126,654 V167L possibly damaging Het
Cd164l2 T C 4: 133,224,254 I172T possibly damaging Het
Clec4g C T 8: 3,718,441 V97M possibly damaging Het
Dnah8 T A 17: 30,694,037 N1068K probably benign Het
Epyc A G 10: 97,649,700 M1V probably null Het
Eya3 A G 4: 132,711,922 E437G possibly damaging Het
Fbln1 C T 15: 85,244,306 T568I possibly damaging Het
Fcrl1 A T 3: 87,391,257 N353I probably damaging Het
Gm10272 A T 10: 77,706,633 H3L probably null Het
Gm15130 A G 2: 111,148,501 S32P unknown Het
Gm20379 C A 13: 92,306,021 probably benign Het
Igf2r A T 17: 12,716,672 Y644N probably damaging Het
Krtap4-9 T C 11: 99,785,280 probably benign Het
Man2c1 A G 9: 57,140,746 N739D probably benign Het
Mcm5 C T 8: 75,109,853 T49M possibly damaging Het
Otof C T 5: 30,405,176 probably null Het
Ptgr2 C T 12: 84,307,894 T283I probably damaging Het
Rhox4c G T X: 37,480,528 G15V probably benign Het
Rnd1 A T 15: 98,670,688 L203H probably damaging Het
Rnf186 A G 4: 138,967,920 N257S probably benign Het
Rsf1 T C 7: 97,679,150 probably benign Het
Ryr2 G A 13: 11,742,023 Q1582* probably null Het
Sntg2 G A 12: 30,267,023 probably benign Het
Spata31d1c A G 13: 65,037,011 D789G probably benign Het
Strc A C 2: 121,372,180 L1168R probably damaging Het
Tmtc3 A T 10: 100,466,131 S319T possibly damaging Het
Vps13d A T 4: 145,074,963 F3531I probably benign Het
Other mutations in Vmn1r88
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01828:Vmn1r88 APN 7 13177735 missense probably damaging 1.00
IGL01879:Vmn1r88 APN 7 13178302 missense probably benign 0.12
IGL02028:Vmn1r88 APN 7 13177792 missense probably benign
IGL02586:Vmn1r88 APN 7 13177808 nonsense probably null
PIT4466001:Vmn1r88 UTSW 7 13178476 missense possibly damaging 0.83
R1163:Vmn1r88 UTSW 7 13178133 missense probably benign
R1478:Vmn1r88 UTSW 7 13177951 missense probably damaging 1.00
R2376:Vmn1r88 UTSW 7 13177858 missense probably damaging 0.99
R3624:Vmn1r88 UTSW 7 13177863 missense probably benign 0.08
R4543:Vmn1r88 UTSW 7 13177980 missense possibly damaging 0.52
R4593:Vmn1r88 UTSW 7 13177842 missense probably damaging 0.96
R4721:Vmn1r88 UTSW 7 13178524 nonsense probably null
R5927:Vmn1r88 UTSW 7 13178513 missense probably benign 0.12
R6411:Vmn1r88 UTSW 7 13178043 missense probably damaging 1.00
R6535:Vmn1r88 UTSW 7 13178185 missense probably benign 0.03
R6598:Vmn1r88 UTSW 7 13178223 missense probably damaging 1.00
R6857:Vmn1r88 UTSW 7 13178331 missense possibly damaging 0.87
Posted On2016-08-02