Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03176:Vmn1r88'

412011

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r88

Ensembl Gene

ENSMUSG00000095902

Gene Name

vomeronasal 1 receptor, 88

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL03176

Quality Score

Status

Chromosome

Chromosomal Location

13177719-13178669 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 13177852 bp

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Valine at position 45 (D45V)

Ref Sequence

ENSEMBL: ENSMUSP00000128946 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171783]

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000122190

Predicted Effect

probably damaging
Transcript: ENSMUST00000171783
AA Change: D45V

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000128946
Gene: ENSMUSG00000095902
AA Change: D45V

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	306	2e-14	PFAM
Pfam:V1R	35	301	1.4e-30	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam23	C	A	1: 63,563,416	P579Q	probably damaging	Het
Adam6a	A	G	12: 113,546,202	T732A	probably benign	Het
Ahnak	T	A	19: 9,008,166	N2271K	possibly damaging	Het
Ahnak	T	C	19: 9,002,449	S366P	probably damaging	Het
Akr1a1	A	G	4: 116,639,075	L213S	probably damaging	Het
Ammecr1l	T	A	18: 31,772,049	D114E	possibly damaging	Het
Casq2	G	T	3: 102,126,654	V167L	possibly damaging	Het
Cd164l2	T	C	4: 133,224,254	I172T	possibly damaging	Het
Clec4g	C	T	8: 3,718,441	V97M	possibly damaging	Het
Dnah8	T	A	17: 30,694,037	N1068K	probably benign	Het
Epyc	A	G	10: 97,649,700	M1V	probably null	Het
Eya3	A	G	4: 132,711,922	E437G	possibly damaging	Het
Fbln1	C	T	15: 85,244,306	T568I	possibly damaging	Het
Fcrl1	A	T	3: 87,391,257	N353I	probably damaging	Het
Gm10272	A	T	10: 77,706,633	H3L	probably null	Het
Gm15130	A	G	2: 111,148,501	S32P	unknown	Het
Gm20379	C	A	13: 92,306,021		probably benign	Het
Igf2r	A	T	17: 12,716,672	Y644N	probably damaging	Het
Krtap4-9	T	C	11: 99,785,280		probably benign	Het
Man2c1	A	G	9: 57,140,746	N739D	probably benign	Het
Mcm5	C	T	8: 75,109,853	T49M	possibly damaging	Het
Otof	C	T	5: 30,405,176		probably null	Het
Ptgr2	C	T	12: 84,307,894	T283I	probably damaging	Het
Rhox4c	G	T	X: 37,480,528	G15V	probably benign	Het
Rnd1	A	T	15: 98,670,688	L203H	probably damaging	Het
Rnf186	A	G	4: 138,967,920	N257S	probably benign	Het
Rsf1	T	C	7: 97,679,150		probably benign	Het
Ryr2	G	A	13: 11,742,023	Q1582*	probably null	Het
Sntg2	G	A	12: 30,267,023		probably benign	Het
Spata31d1c	A	G	13: 65,037,011	D789G	probably benign	Het
Strc	A	C	2: 121,372,180	L1168R	probably damaging	Het
Tmtc3	A	T	10: 100,466,131	S319T	possibly damaging	Het
Vps13d	A	T	4: 145,074,963	F3531I	probably benign	Het

Other mutations in Vmn1r88

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01828:Vmn1r88	APN	7	13177735	missense	probably damaging	1.00
IGL01879:Vmn1r88	APN	7	13178302	missense	probably benign	0.12
IGL02028:Vmn1r88	APN	7	13177792	missense	probably benign
IGL02586:Vmn1r88	APN	7	13177808	nonsense	probably null
PIT4466001:Vmn1r88	UTSW	7	13178476	missense	possibly damaging	0.83
R1163:Vmn1r88	UTSW	7	13178133	missense	probably benign
R1478:Vmn1r88	UTSW	7	13177951	missense	probably damaging	1.00
R2376:Vmn1r88	UTSW	7	13177858	missense	probably damaging	0.99
R3624:Vmn1r88	UTSW	7	13177863	missense	probably benign	0.08
R4543:Vmn1r88	UTSW	7	13177980	missense	possibly damaging	0.52
R4593:Vmn1r88	UTSW	7	13177842	missense	probably damaging	0.96
R4721:Vmn1r88	UTSW	7	13178524	nonsense	probably null
R5927:Vmn1r88	UTSW	7	13178513	missense	probably benign	0.12
R6411:Vmn1r88	UTSW	7	13178043	missense	probably damaging	1.00
R6535:Vmn1r88	UTSW	7	13178185	missense	probably benign	0.03
R6598:Vmn1r88	UTSW	7	13178223	missense	probably damaging	1.00
R6857:Vmn1r88	UTSW	7	13178331	missense	possibly damaging	0.87

Posted On

2016-08-02