Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03181:Hectd4'

412253

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Hectd4

Ensembl Gene

ENSMUSG00000042744

Gene Name

HECT domain E3 ubiquitin protein ligase 4

Synonyms

Gm15800

Accession Numbers

Essential gene?

Probably essential (E-score: 0.934) question?

Stock #

IGL03181

Quality Score

Status

Chromosome

Chromosomal Location

121220219-121368577 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 121353958 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Cysteine at position 3787 (S3787C)

Ref Sequence

ENSEMBL: ENSMUSP00000048345 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042614]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000042614
AA Change: S3787C

PolyPhen 2 Score 0.906 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000048345
Gene: ENSMUSG00000042744
AA Change: S3787C

Domain	Start	End	E-Value	Type
low complexity region	224	234	N/A	INTRINSIC
low complexity region	266	282	N/A	INTRINSIC
low complexity region	553	564	N/A	INTRINSIC
low complexity region	725	735	N/A	INTRINSIC
low complexity region	1252	1265	N/A	INTRINSIC
coiled coil region	1372	1398	N/A	INTRINSIC
low complexity region	1551	1562	N/A	INTRINSIC
low complexity region	1725	1741	N/A	INTRINSIC
low complexity region	1892	1904	N/A	INTRINSIC
low complexity region	2656	2666	N/A	INTRINSIC
low complexity region	2857	2872	N/A	INTRINSIC
low complexity region	2901	2917	N/A	INTRINSIC
low complexity region	2921	2933	N/A	INTRINSIC
low complexity region	3232	3246	N/A	INTRINSIC
low complexity region	3275	3335	N/A	INTRINSIC
low complexity region	3441	3448	N/A	INTRINSIC
low complexity region	3473	3506	N/A	INTRINSIC
low complexity region	3512	3533	N/A	INTRINSIC
low complexity region	3540	3554	N/A	INTRINSIC
low complexity region	3794	3822	N/A	INTRINSIC
HECTc	4048	4412	4.78e-11	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000104159

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2700049A03Rik	T	C	12: 71,193,373 (GRCm38)	V1319A	possibly damaging	Het
Abcb11	T	A	2: 69,328,008 (GRCm38)		probably benign	Het
Acss3	G	T	10: 107,053,388 (GRCm38)	H190Q	probably damaging	Het
Adra2b	C	T	2: 127,363,983 (GRCm38)	T140I	probably benign	Het
Arl1	T	A	10: 88,743,059 (GRCm38)		probably benign	Het
Atp4a	T	G	7: 30,724,704 (GRCm38)	C968G	probably benign	Het
BC003331	G	T	1: 150,363,539 (GRCm38)	P378T	probably benign	Het
Clec4n	T	C	6: 123,230,515 (GRCm38)	C13R	possibly damaging	Het
Cnot3	T	C	7: 3,653,248 (GRCm38)	Y178H	probably damaging	Het
Col18a1	G	A	10: 77,055,698 (GRCm38)	R1560C	probably damaging	Het
Cyp2c66	T	C	19: 39,142,039 (GRCm38)	F106S	probably benign	Het
Dcn	A	C	10: 97,483,452 (GRCm38)	E30D	probably damaging	Het
Dennd5a	A	T	7: 109,933,658 (GRCm38)	F302I	probably damaging	Het
Dip2b	T	C	15: 100,215,207 (GRCm38)	V1501A	probably damaging	Het
Dnah10	C	T	5: 124,748,457 (GRCm38)	P687S	probably damaging	Het
Drc7	A	G	8: 95,068,127 (GRCm38)	T387A	probably benign	Het
Dusp7	T	A	9: 106,373,810 (GRCm38)	M378K	probably damaging	Het
Ftmt	T	C	18: 52,331,881 (GRCm38)	Y90H	probably damaging	Het
Glb1l3	T	C	9: 26,828,363 (GRCm38)		probably null	Het
Gm884	A	T	11: 103,616,416 (GRCm38)		probably benign	Het
Gpatch3	T	C	4: 133,578,122 (GRCm38)	F223L	probably damaging	Het
Gpr158	T	A	2: 21,783,161 (GRCm38)	F538I	probably benign	Het
Gucy2e	A	G	11: 69,230,182 (GRCm38)		probably benign	Het
Hadha	A	G	5: 30,121,526 (GRCm38)	V566A	probably benign	Het
Hnrnpk	A	T	13: 58,394,316 (GRCm38)	D265E	possibly damaging	Het
Hspbp1	G	A	7: 4,684,364 (GRCm38)	R83W	probably damaging	Het
Hspg2	T	A	4: 137,515,937 (GRCm38)	L758Q	probably damaging	Het
Ippk	A	G	13: 49,441,987 (GRCm38)	Y180C	probably damaging	Het
Itpr3	T	A	17: 27,111,268 (GRCm38)	M1620K	probably benign	Het
Klf7	T	C	1: 64,035,726 (GRCm38)	K298R	possibly damaging	Het
Ktn1	A	T	14: 47,733,284 (GRCm38)	T1229S	probably benign	Het
Lefty2	A	G	1: 180,897,550 (GRCm38)	N282D	probably damaging	Het
Nsd1	G	A	13: 55,247,045 (GRCm38)	E820K	probably damaging	Het
Obsl1	C	A	1: 75,492,584 (GRCm38)	A1238S	probably benign	Het
Pias2	T	C	18: 77,133,242 (GRCm38)	I391T	possibly damaging	Het
Ppp1r10	G	T	17: 35,930,624 (GRCm38)	G764*	probably null	Het
Ptpra	T	C	2: 130,517,787 (GRCm38)	F158L	probably damaging	Het
Recql	T	C	6: 142,378,192 (GRCm38)	S59G	probably benign	Het
Rrp1b	A	T	17: 32,057,176 (GRCm38)	I566F	probably benign	Het
Sh3yl1	G	A	12: 30,941,980 (GRCm38)	D145N	possibly damaging	Het
Slc35f5	T	A	1: 125,585,185 (GRCm38)	I52N	probably damaging	Het
Slc51b	A	G	9: 65,415,165 (GRCm38)		probably null	Het
Smpd4	C	T	16: 17,625,807 (GRCm38)	Q72*	probably null	Het
Spata6	A	G	4: 111,822,766 (GRCm38)	D391G	probably benign	Het
Tnc	T	A	4: 63,967,306 (GRCm38)	D1853V	possibly damaging	Het
Tnks1bp1	C	T	2: 85,062,714 (GRCm38)	T333I	probably benign	Het
Vmn2r100	T	A	17: 19,531,945 (GRCm38)	I813N	probably damaging	Het
Vwa8	T	A	14: 79,009,250 (GRCm38)	H677Q	probably benign	Het
Washc4	T	C	10: 83,591,019 (GRCm38)	Y1064H	probably damaging	Het
Wdr82	T	A	9: 106,186,415 (GRCm38)	I272K	probably benign	Het
Zc3h12a	T	C	4: 125,119,304 (GRCm38)	Y589C	probably damaging	Het

Other mutations in Hectd4

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00156:Hectd4	APN	5	121,363,870 (GRCm38)	missense	possibly damaging	0.51
IGL00976:Hectd4	APN	5	121,349,106 (GRCm38)	missense	probably benign	0.18
IGL01085:Hectd4	APN	5	121,331,701 (GRCm38)	missense	probably damaging	1.00
IGL01112:Hectd4	APN	5	121,306,950 (GRCm38)	missense	probably benign	0.01
IGL01402:Hectd4	APN	5	121,339,417 (GRCm38)	splice site	probably benign
IGL01474:Hectd4	APN	5	121,336,649 (GRCm38)	missense	possibly damaging	0.53
IGL01503:Hectd4	APN	5	121,318,651 (GRCm38)	missense	probably benign	0.28
IGL01548:Hectd4	APN	5	121,364,660 (GRCm38)	missense	possibly damaging	0.71
IGL01656:Hectd4	APN	5	121,322,700 (GRCm38)	missense	probably damaging	0.99
IGL01756:Hectd4	APN	5	121,344,824 (GRCm38)	missense	probably benign	0.28
IGL01819:Hectd4	APN	5	121,328,418 (GRCm38)	missense	possibly damaging	0.85
IGL02080:Hectd4	APN	5	121,366,606 (GRCm38)	utr 3 prime	probably benign
IGL02488:Hectd4	APN	5	121,292,087 (GRCm38)	missense	probably benign	0.33
IGL02490:Hectd4	APN	5	121,318,613 (GRCm38)	missense	possibly damaging	0.82
IGL02558:Hectd4	APN	5	121,344,785 (GRCm38)	missense	probably benign	0.28
IGL02626:Hectd4	APN	5	121,353,881 (GRCm38)	missense	possibly damaging	0.86
IGL02649:Hectd4	APN	5	121,349,402 (GRCm38)	missense	possibly damaging	0.73
IGL02736:Hectd4	APN	5	121,342,719 (GRCm38)	missense	possibly damaging	0.73
IGL02861:Hectd4	APN	5	121,307,004 (GRCm38)	missense	possibly damaging	0.81
IGL02880:Hectd4	APN	5	121,365,053 (GRCm38)	missense	possibly damaging	0.93
IGL02889:Hectd4	APN	5	121,365,053 (GRCm38)	missense	possibly damaging	0.93
IGL02953:Hectd4	APN	5	121,365,053 (GRCm38)	missense	possibly damaging	0.93
IGL02969:Hectd4	APN	5	121,365,053 (GRCm38)	missense	possibly damaging	0.93
IGL03031:Hectd4	APN	5	121,348,794 (GRCm38)	missense	possibly damaging	0.96
IGL03066:Hectd4	APN	5	121,365,053 (GRCm38)	missense	possibly damaging	0.93
IGL03160:Hectd4	APN	5	121,259,879 (GRCm38)	missense	probably benign
IGL03265:Hectd4	APN	5	121,259,939 (GRCm38)	splice site	probably benign
IGL03375:Hectd4	APN	5	121,328,382 (GRCm38)	missense	possibly damaging	0.72
Achilles	UTSW	5	121,307,381 (GRCm38)	nonsense	probably null
agamemnon	UTSW	5	121,253,858 (GRCm38)	splice site	probably benign
clymnestra	UTSW	5	121,334,375 (GRCm38)	missense	possibly damaging	0.86
hector	UTSW	5	121,315,437 (GRCm38)	missense	probably damaging	1.00
helen	UTSW	5	121,310,663 (GRCm38)	missense	probably damaging	0.97
Merriwether	UTSW	5	121,353,551 (GRCm38)	missense	possibly damaging	0.53
PIT4466001:Hectd4	UTSW	5	121,333,060 (GRCm38)	critical splice donor site	probably null
R0018:Hectd4	UTSW	5	121,254,179 (GRCm38)	missense	possibly damaging	0.53
R0024:Hectd4	UTSW	5	121,308,576 (GRCm38)	missense	possibly damaging	0.92
R0030:Hectd4	UTSW	5	121,262,588 (GRCm38)	nonsense	probably null
R0080:Hectd4	UTSW	5	121,349,372 (GRCm38)	missense	probably benign	0.18
R0110:Hectd4	UTSW	5	121,305,673 (GRCm38)	missense	possibly damaging	0.53
R0110:Hectd4	UTSW	5	121,281,896 (GRCm38)	missense	possibly damaging	0.90
R0115:Hectd4	UTSW	5	121,295,506 (GRCm38)	splice site	probably benign
R0128:Hectd4	UTSW	5	121,349,243 (GRCm38)	missense	possibly damaging	0.86
R0131:Hectd4	UTSW	5	121,333,024 (GRCm38)	missense	probably benign	0.44
R0131:Hectd4	UTSW	5	121,333,024 (GRCm38)	missense	probably benign	0.44
R0132:Hectd4	UTSW	5	121,333,024 (GRCm38)	missense	probably benign	0.44
R0244:Hectd4	UTSW	5	121,329,605 (GRCm38)	missense	probably benign	0.33
R0281:Hectd4	UTSW	5	121,254,251 (GRCm38)	missense	possibly damaging	0.85
R0329:Hectd4	UTSW	5	121,259,864 (GRCm38)	missense	probably benign
R0410:Hectd4	UTSW	5	121,286,266 (GRCm38)	missense	possibly damaging	0.86
R0422:Hectd4	UTSW	5	121,343,082 (GRCm38)	splice site	probably null
R0442:Hectd4	UTSW	5	121,323,982 (GRCm38)	missense	possibly damaging	0.66
R0449:Hectd4	UTSW	5	121,364,590 (GRCm38)	splice site	probably null
R0469:Hectd4	UTSW	5	121,305,673 (GRCm38)	missense	possibly damaging	0.53
R0469:Hectd4	UTSW	5	121,281,896 (GRCm38)	missense	possibly damaging	0.90
R0481:Hectd4	UTSW	5	121,295,506 (GRCm38)	splice site	probably benign
R0510:Hectd4	UTSW	5	121,305,673 (GRCm38)	missense	possibly damaging	0.53
R0510:Hectd4	UTSW	5	121,281,896 (GRCm38)	missense	possibly damaging	0.90
R0520:Hectd4	UTSW	5	121,331,707 (GRCm38)	missense	possibly damaging	0.53
R0534:Hectd4	UTSW	5	121,348,476 (GRCm38)	missense	possibly damaging	0.96
R0603:Hectd4	UTSW	5	121,304,337 (GRCm38)	missense	possibly damaging	0.46
R0617:Hectd4	UTSW	5	121,343,232 (GRCm38)	splice site	probably benign
R0622:Hectd4	UTSW	5	121,348,625 (GRCm38)	missense	possibly damaging	0.53
R0626:Hectd4	UTSW	5	121,277,824 (GRCm38)	missense	probably benign	0.18
R0708:Hectd4	UTSW	5	121,286,463 (GRCm38)	critical splice donor site	probably null
R0710:Hectd4	UTSW	5	121,336,628 (GRCm38)	missense	probably benign	0.08
R0763:Hectd4	UTSW	5	121,307,033 (GRCm38)	unclassified	probably benign
R0764:Hectd4	UTSW	5	121,286,769 (GRCm38)	missense	possibly damaging	0.46
R1123:Hectd4	UTSW	5	121,286,736 (GRCm38)	missense	probably damaging	0.96
R1129:Hectd4	UTSW	5	121,310,599 (GRCm38)	missense	possibly damaging	0.66
R1204:Hectd4	UTSW	5	121,350,485 (GRCm38)	missense	possibly damaging	0.85
R1237:Hectd4	UTSW	5	121,321,507 (GRCm38)	missense	possibly damaging	0.90
R1257:Hectd4	UTSW	5	121,318,624 (GRCm38)	nonsense	probably null
R1391:Hectd4	UTSW	5	121,353,695 (GRCm38)	missense	possibly damaging	0.96
R1395:Hectd4	UTSW	5	121,328,513 (GRCm38)	critical splice donor site	probably null
R1468:Hectd4	UTSW	5	121,349,172 (GRCm38)	missense	possibly damaging	0.65
R1468:Hectd4	UTSW	5	121,349,172 (GRCm38)	missense	possibly damaging	0.65
R1545:Hectd4	UTSW	5	121,323,956 (GRCm38)	missense	possibly damaging	0.87
R1553:Hectd4	UTSW	5	121,349,259 (GRCm38)	missense	probably benign	0.00
R1572:Hectd4	UTSW	5	121,301,878 (GRCm38)	missense	possibly damaging	0.85
R1662:Hectd4	UTSW	5	121,317,245 (GRCm38)	missense	probably benign	0.01
R1705:Hectd4	UTSW	5	121,298,104 (GRCm38)	missense	probably benign
R1715:Hectd4	UTSW	5	121,344,818 (GRCm38)	missense	possibly damaging	0.85
R1728:Hectd4	UTSW	5	121,301,839 (GRCm38)	missense	possibly damaging	0.51
R1736:Hectd4	UTSW	5	121,349,530 (GRCm38)	missense	possibly damaging	0.53
R1768:Hectd4	UTSW	5	121,358,303 (GRCm38)	missense	possibly damaging	0.70
R1775:Hectd4	UTSW	5	121,291,191 (GRCm38)	splice site	probably benign
R1784:Hectd4	UTSW	5	121,301,839 (GRCm38)	missense	possibly damaging	0.51
R1843:Hectd4	UTSW	5	121,297,180 (GRCm38)	missense	possibly damaging	0.53
R1914:Hectd4	UTSW	5	121,322,294 (GRCm38)	missense	probably benign	0.08
R1915:Hectd4	UTSW	5	121,322,294 (GRCm38)	missense	probably benign	0.08
R2024:Hectd4	UTSW	5	121,281,918 (GRCm38)	missense	possibly damaging	0.86
R2103:Hectd4	UTSW	5	121,355,629 (GRCm38)	missense	probably benign	0.04
R2108:Hectd4	UTSW	5	121,333,424 (GRCm38)	missense	possibly damaging	0.72
R2124:Hectd4	UTSW	5	121,318,639 (GRCm38)	missense	probably damaging	0.97
R2150:Hectd4	UTSW	5	121,253,858 (GRCm38)	splice site	probably benign
R2192:Hectd4	UTSW	5	121,315,143 (GRCm38)	missense	possibly damaging	0.46
R2301:Hectd4	UTSW	5	121,353,537 (GRCm38)	missense	probably benign	0.18
R2324:Hectd4	UTSW	5	121,315,437 (GRCm38)	missense	probably damaging	1.00
R2331:Hectd4	UTSW	5	121,320,026 (GRCm38)	missense	probably benign	0.05
R2504:Hectd4	UTSW	5	121,263,967 (GRCm38)	missense	possibly damaging	0.73
R2504:Hectd4	UTSW	5	121,220,620 (GRCm38)	missense	unknown
R2904:Hectd4	UTSW	5	121,292,724 (GRCm38)	splice site	probably benign
R3843:Hectd4	UTSW	5	121,259,873 (GRCm38)	missense	possibly damaging	0.72
R3934:Hectd4	UTSW	5	121,320,101 (GRCm38)	critical splice donor site	probably null
R3944:Hectd4	UTSW	5	121,303,525 (GRCm38)	splice site	probably benign
R4133:Hectd4	UTSW	5	121,277,834 (GRCm38)	critical splice donor site	probably null
R4271:Hectd4	UTSW	5	121,220,504 (GRCm38)	small deletion	probably benign
R4413:Hectd4	UTSW	5	121,350,481 (GRCm38)	missense	possibly damaging	0.53
R4456:Hectd4	UTSW	5	121,308,271 (GRCm38)	missense	possibly damaging	0.65
R4489:Hectd4	UTSW	5	121,286,257 (GRCm38)	missense	possibly damaging	0.73
R4539:Hectd4	UTSW	5	121,314,907 (GRCm38)	nonsense	probably null
R4564:Hectd4	UTSW	5	121,350,431 (GRCm38)	missense	probably benign	0.33
R4582:Hectd4	UTSW	5	121,286,419 (GRCm38)	missense	possibly damaging	0.53
R4629:Hectd4	UTSW	5	121,297,203 (GRCm38)	missense	probably benign	0.01
R4633:Hectd4	UTSW	5	121,349,216 (GRCm38)	missense	probably benign	0.33
R4643:Hectd4	UTSW	5	121,349,055 (GRCm38)	missense	possibly damaging	0.53
R4679:Hectd4	UTSW	5	121,325,251 (GRCm38)	missense	possibly damaging	0.72
R4681:Hectd4	UTSW	5	121,303,615 (GRCm38)	missense	possibly damaging	0.86
R4734:Hectd4	UTSW	5	121,341,977 (GRCm38)	missense	possibly damaging	0.53
R4739:Hectd4	UTSW	5	121,348,442 (GRCm38)	missense	probably benign
R4781:Hectd4	UTSW	5	121,306,107 (GRCm38)	critical splice donor site	probably null
R4860:Hectd4	UTSW	5	121,305,818 (GRCm38)	missense	probably benign	0.04
R4860:Hectd4	UTSW	5	121,305,818 (GRCm38)	missense	probably benign	0.04
R4869:Hectd4	UTSW	5	121,322,672 (GRCm38)	missense	possibly damaging	0.46
R4909:Hectd4	UTSW	5	121,263,891 (GRCm38)	missense	probably benign	0.18
R4922:Hectd4	UTSW	5	121,359,315 (GRCm38)	missense	possibly damaging	0.86
R4925:Hectd4	UTSW	5	121,322,690 (GRCm38)	missense	possibly damaging	0.83
R5004:Hectd4	UTSW	5	121,329,565 (GRCm38)	missense	possibly damaging	0.93
R5004:Hectd4	UTSW	5	121,328,199 (GRCm38)	splice site	probably null
R5129:Hectd4	UTSW	5	121,343,510 (GRCm38)	missense	possibly damaging	0.87
R5217:Hectd4	UTSW	5	121,353,551 (GRCm38)	missense	possibly damaging	0.53
R5267:Hectd4	UTSW	5	121,344,824 (GRCm38)	missense	probably benign	0.28
R5344:Hectd4	UTSW	5	121,343,676 (GRCm38)	missense	probably benign	0.28
R5345:Hectd4	UTSW	5	121,263,974 (GRCm38)	missense	possibly damaging	0.85
R5347:Hectd4	UTSW	5	121,304,448 (GRCm38)	missense	probably benign	0.33
R5360:Hectd4	UTSW	5	121,315,401 (GRCm38)	missense	possibly damaging	0.90
R5363:Hectd4	UTSW	5	121,310,603 (GRCm38)	missense	probably benign	0.04
R5445:Hectd4	UTSW	5	121,266,274 (GRCm38)	missense	probably benign	0.00
R5479:Hectd4	UTSW	5	121,306,948 (GRCm38)	missense	probably benign
R5507:Hectd4	UTSW	5	121,281,101 (GRCm38)	missense	unknown
R5552:Hectd4	UTSW	5	121,342,851 (GRCm38)	missense	possibly damaging	0.96
R5691:Hectd4	UTSW	5	121,348,815 (GRCm38)	missense	possibly damaging	0.85
R5745:Hectd4	UTSW	5	121,353,502 (GRCm38)	missense	possibly damaging	0.96
R5757:Hectd4	UTSW	5	121,348,619 (GRCm38)	missense	possibly damaging	0.72
R5845:Hectd4	UTSW	5	121,307,524 (GRCm38)	critical splice donor site	probably null
R5869:Hectd4	UTSW	5	121,343,225 (GRCm38)	critical splice donor site	probably null
R5913:Hectd4	UTSW	5	121,323,974 (GRCm38)	missense	possibly damaging	0.83
R5920:Hectd4	UTSW	5	121,308,271 (GRCm38)	missense	possibly damaging	0.65
R5943:Hectd4	UTSW	5	121,322,294 (GRCm38)	missense	probably benign	0.01
R6219:Hectd4	UTSW	5	121,308,878 (GRCm38)	missense	possibly damaging	0.92
R6250:Hectd4	UTSW	5	121,339,498 (GRCm38)	missense	possibly damaging	0.85
R6301:Hectd4	UTSW	5	121,254,220 (GRCm38)	missense	possibly damaging	0.91
R6428:Hectd4	UTSW	5	121,350,445 (GRCm38)	missense	possibly damaging	0.53
R6446:Hectd4	UTSW	5	121,334,375 (GRCm38)	missense	possibly damaging	0.86
R6453:Hectd4	UTSW	5	121,350,592 (GRCm38)	missense	probably damaging	1.00
R6513:Hectd4	UTSW	5	121,356,196 (GRCm38)	splice site	probably null
R6540:Hectd4	UTSW	5	121,303,571 (GRCm38)	missense	probably benign	0.33
R6706:Hectd4	UTSW	5	121,320,084 (GRCm38)	missense	possibly damaging	0.92
R6720:Hectd4	UTSW	5	121,307,381 (GRCm38)	nonsense	probably null
R6736:Hectd4	UTSW	5	121,277,725 (GRCm38)	missense	possibly damaging	0.86
R6776:Hectd4	UTSW	5	121,353,511 (GRCm38)	missense	possibly damaging	0.85
R7033:Hectd4	UTSW	5	121,364,568 (GRCm38)	missense	possibly damaging	0.86
R7038:Hectd4	UTSW	5	121,299,597 (GRCm38)	missense	possibly damaging	0.90
R7175:Hectd4	UTSW	5	121,273,629 (GRCm38)	missense	possibly damaging	0.85
R7180:Hectd4	UTSW	5	121,308,342 (GRCm38)	missense	probably benign	0.01
R7234:Hectd4	UTSW	5	121,329,073 (GRCm38)	missense	possibly damaging	0.53
R7253:Hectd4	UTSW	5	121,314,881 (GRCm38)	missense	possibly damaging	0.66
R7349:Hectd4	UTSW	5	121,310,663 (GRCm38)	missense	probably damaging	0.97
R7450:Hectd4	UTSW	5	121,281,932 (GRCm38)	missense	probably benign	0.00
R7467:Hectd4	UTSW	5	121,323,961 (GRCm38)	missense	possibly damaging	0.66
R7475:Hectd4	UTSW	5	121,358,133 (GRCm38)	splice site	probably null
R7482:Hectd4	UTSW	5	121,363,878 (GRCm38)	missense	possibly damaging	0.71
R7512:Hectd4	UTSW	5	121,297,109 (GRCm38)	missense	possibly damaging	0.72
R7525:Hectd4	UTSW	5	121,343,665 (GRCm38)	missense	possibly damaging	0.70
R7559:Hectd4	UTSW	5	121,315,510 (GRCm38)	splice site	probably null
R7560:Hectd4	UTSW	5	121,254,342 (GRCm38)	missense	possibly damaging	0.53
R7561:Hectd4	UTSW	5	121,291,225 (GRCm38)	missense	possibly damaging	0.91
R7576:Hectd4	UTSW	5	121,349,459 (GRCm38)	missense	possibly damaging	0.91
R7584:Hectd4	UTSW	5	121,318,735 (GRCm38)	missense	possibly damaging	0.83
R7648:Hectd4	UTSW	5	121,254,371 (GRCm38)	missense	possibly damaging	0.73
R7663:Hectd4	UTSW	5	121,324,031 (GRCm38)	missense	probably benign	0.06
R7692:Hectd4	UTSW	5	121,321,564 (GRCm38)	missense	possibly damaging	0.46
R7725:Hectd4	UTSW	5	121,220,617 (GRCm38)	missense	unknown
R7731:Hectd4	UTSW	5	121,307,014 (GRCm38)	missense	probably benign	0.00
R7732:Hectd4	UTSW	5	121,336,629 (GRCm38)	missense	probably benign	0.14
R7782:Hectd4	UTSW	5	121,305,721 (GRCm38)	missense	possibly damaging	0.53
R7854:Hectd4	UTSW	5	121,329,568 (GRCm38)	missense	probably benign	0.27
R7898:Hectd4	UTSW	5	121,331,817 (GRCm38)	missense	probably benign	0.18
R7910:Hectd4	UTSW	5	121,254,228 (GRCm38)	missense	possibly damaging	0.86
R7962:Hectd4	UTSW	5	121,310,629 (GRCm38)	missense	probably damaging	0.98
R8003:Hectd4	UTSW	5	121,339,518 (GRCm38)	missense	possibly damaging	0.85
R8098:Hectd4	UTSW	5	121,321,398 (GRCm38)	missense	possibly damaging	0.46
R8110:Hectd4	UTSW	5	121,332,949 (GRCm38)	missense	possibly damaging	0.96
R8118:Hectd4	UTSW	5	121,286,376 (GRCm38)	missense	probably benign	0.33
R8171:Hectd4	UTSW	5	121,318,756 (GRCm38)	missense	possibly damaging	0.82
R8234:Hectd4	UTSW	5	121,339,544 (GRCm38)	missense	possibly damaging	0.72
R8289:Hectd4	UTSW	5	121,266,361 (GRCm38)	missense	possibly damaging	0.53
R8292:Hectd4	UTSW	5	121,317,225 (GRCm38)	missense	possibly damaging	0.66
R8348:Hectd4	UTSW	5	121,220,256 (GRCm38)	start gained	probably benign
R8397:Hectd4	UTSW	5	121,259,894 (GRCm38)	missense	probably damaging	0.98
R8436:Hectd4	UTSW	5	121,308,358 (GRCm38)	missense	possibly damaging	0.90
R8436:Hectd4	UTSW	5	121,343,147 (GRCm38)	missense	probably benign	0.00
R8443:Hectd4	UTSW	5	121,329,109 (GRCm38)	missense	possibly damaging	0.72
R8448:Hectd4	UTSW	5	121,220,256 (GRCm38)	start gained	probably benign
R8516:Hectd4	UTSW	5	121,349,010 (GRCm38)	missense	possibly damaging	0.53
R8519:Hectd4	UTSW	5	121,304,426 (GRCm38)	nonsense	probably null
R8553:Hectd4	UTSW	5	121,353,598 (GRCm38)	missense	possibly damaging	0.73
R8557:Hectd4	UTSW	5	121,310,651 (GRCm38)	missense	possibly damaging	0.66
R8725:Hectd4	UTSW	5	121,350,494 (GRCm38)	missense	probably damaging	1.00
R8751:Hectd4	UTSW	5	121,363,775 (GRCm38)	nonsense	probably null
R8769:Hectd4	UTSW	5	121,281,873 (GRCm38)	missense	possibly damaging	0.53
R8803:Hectd4	UTSW	5	121,323,931 (GRCm38)	missense	probably benign	0.01
R8887:Hectd4	UTSW	5	121,295,478 (GRCm38)	missense	probably benign	0.44
R8982:Hectd4	UTSW	5	121,328,242 (GRCm38)	missense	probably benign	0.02
R8988:Hectd4	UTSW	5	121,277,756 (GRCm38)	missense	possibly damaging	0.86
R8991:Hectd4	UTSW	5	121,358,284 (GRCm38)	missense	probably benign	0.33
R8994:Hectd4	UTSW	5	121,303,566 (GRCm38)	missense	probably benign	0.33
R8995:Hectd4	UTSW	5	121,254,359 (GRCm38)	missense	possibly damaging	0.96
R9049:Hectd4	UTSW	5	121,313,892 (GRCm38)	missense	possibly damaging	0.92
R9093:Hectd4	UTSW	5	121,273,614 (GRCm38)	missense	probably benign	0.14
R9106:Hectd4	UTSW	5	121,329,556 (GRCm38)	missense	possibly damaging	0.53
R9137:Hectd4	UTSW	5	121,358,175 (GRCm38)	missense	possibly damaging	0.53
R9146:Hectd4	UTSW	5	121,349,034 (GRCm38)	missense	probably benign	0.33
R9154:Hectd4	UTSW	5	121,253,904 (GRCm38)	missense
R9162:Hectd4	UTSW	5	121,306,979 (GRCm38)	missense	possibly damaging	0.66
R9166:Hectd4	UTSW	5	121,308,627 (GRCm38)	missense	probably damaging	0.96
R9183:Hectd4	UTSW	5	121,299,488 (GRCm38)	missense	possibly damaging	0.51
R9207:Hectd4	UTSW	5	121,295,433 (GRCm38)	missense	possibly damaging	0.86
R9291:Hectd4	UTSW	5	121,348,965 (GRCm38)	missense	probably benign	0.14
R9300:Hectd4	UTSW	5	121,348,889 (GRCm38)	missense	probably benign	0.33
R9314:Hectd4	UTSW	5	121,299,645 (GRCm38)	critical splice donor site	probably null
R9381:Hectd4	UTSW	5	121,334,429 (GRCm38)	missense	possibly damaging	0.53
R9432:Hectd4	UTSW	5	121,322,801 (GRCm38)	missense	probably benign	0.01
R9491:Hectd4	UTSW	5	121,314,918 (GRCm38)	missense	probably damaging	0.97
R9532:Hectd4	UTSW	5	121,364,553 (GRCm38)	missense	probably benign	0.00
R9557:Hectd4	UTSW	5	121,321,554 (GRCm38)	missense	possibly damaging	0.66
R9561:Hectd4	UTSW	5	121,334,469 (GRCm38)	missense	possibly damaging	0.53
R9593:Hectd4	UTSW	5	121,286,781 (GRCm38)	nonsense	probably null
R9704:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9705:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9712:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9713:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9726:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9732:Hectd4	UTSW	5	121,254,191 (GRCm38)	nonsense	probably null
R9750:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9752:Hectd4	UTSW	5	121,334,352 (GRCm38)	missense	possibly damaging	0.85
R9752:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
R9772:Hectd4	UTSW	5	121,310,681 (GRCm38)	missense	probably benign	0.00
X0026:Hectd4	UTSW	5	121,349,637 (GRCm38)	missense	probably benign	0.04
X0027:Hectd4	UTSW	5	121,321,404 (GRCm38)	missense	probably benign	0.27
Z1088:Hectd4	UTSW	5	121,295,503 (GRCm38)	splice site	probably null
Z1177:Hectd4	UTSW	5	121,358,320 (GRCm38)	missense	probably benign

Posted On

2016-08-02