Incidental Mutation 'IGL03182:Vmn1r83'
ID412273
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r83
Ensembl Gene ENSMUSG00000066804
Gene Namevomeronasal 1 receptor 83
SynonymsV1rg8
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.061) question?
Stock #IGL03182
Quality Score
Status
Chromosome7
Chromosomal Location12319707-12329481 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 12321690 bp
ZygosityHeterozygous
Amino Acid Change Methionine to Valine at position 147 (M147V)
Ref Sequence ENSEMBL: ENSMUSP00000154521 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000086229] [ENSMUST00000226701]
Predicted Effect probably benign
Transcript: ENSMUST00000086229
AA Change: M147V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000083406
Gene: ENSMUSG00000066804
AA Change: M147V

DomainStartEndE-ValueType
Pfam:TAS2R 1 303 1.3e-8 PFAM
Pfam:V1R 26 299 1.7e-28 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226701
AA Change: M147V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 42 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Agbl3 A T 6: 34,803,500 K469N probably damaging Het
Aldh2 A G 5: 121,580,724 probably benign Het
Ankfy1 T C 11: 72,728,754 probably benign Het
Ankhd1 C T 18: 36,578,774 T209I probably benign Het
Aox3 G A 1: 58,165,887 V754I probably benign Het
Arfgef3 C T 10: 18,600,544 R1509H probably damaging Het
AU019823 T C 9: 50,612,398 N50S possibly damaging Het
Ccdc157 A G 11: 4,151,832 S30P probably damaging Het
Cept1 T A 3: 106,504,550 E369D probably damaging Het
Clcnka T C 4: 141,394,487 Y236C probably damaging Het
Ddx42 A T 11: 106,247,527 L717F probably benign Het
Dnah11 A T 12: 118,030,291 I2340N probably damaging Het
Dsel T C 1: 111,860,138 E889G probably damaging Het
Fasn T C 11: 120,812,726 Y1560C probably damaging Het
Fermt2 A T 14: 45,461,768 M623K possibly damaging Het
Gm21970 T A 16: 91,393,838 S110T possibly damaging Het
Gm826 T A 2: 160,327,115 R91S unknown Het
Lrrn3 A G 12: 41,454,021 L99S probably damaging Het
Megf8 T A 7: 25,347,348 M1552K possibly damaging Het
Mgll G T 6: 88,823,191 V191F probably damaging Het
Nol8 C A 13: 49,664,081 H778N probably damaging Het
Olfr1090 A T 2: 86,754,022 S239T probably damaging Het
Olfr1471 A C 19: 13,445,443 T144P possibly damaging Het
Olfr385 T A 11: 73,589,442 T99S probably benign Het
Olfr948 A T 9: 39,318,981 M211K probably benign Het
Pfkfb3 A T 2: 11,501,663 I13N probably damaging Het
Pim1 T A 17: 29,491,766 D114E possibly damaging Het
Pkd1 T C 17: 24,573,818 L1493P probably damaging Het
Plb1 A T 5: 32,344,915 probably benign Het
Plch1 A T 3: 63,702,594 Y872* probably null Het
Rictor A G 15: 6,789,598 D1434G probably benign Het
Rptor G A 11: 119,725,145 G162R probably damaging Het
Serping1 T C 2: 84,765,818 D424G probably damaging Het
Slit2 A G 5: 48,220,053 I475V possibly damaging Het
Snx31 G T 15: 36,525,687 Q289K probably benign Het
Tbc1d13 G A 2: 30,147,367 A254T probably damaging Het
Tek T C 4: 94,851,765 I750T probably damaging Het
Tet2 A T 3: 133,471,398 L1296* probably null Het
Tmem145 T A 7: 25,314,879 F459I probably damaging Het
Uba5 A T 9: 104,054,129 V247D possibly damaging Het
Vwde T C 6: 13,187,139 D783G probably damaging Het
Zfp609 A G 9: 65,701,005 S1198P probably benign Het
Other mutations in Vmn1r83
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01371:Vmn1r83 APN 7 12321233 missense probably benign 0.10
IGL01447:Vmn1r83 APN 7 12321497 missense probably benign
IGL01793:Vmn1r83 APN 7 12321577 missense probably benign 0.02
IGL02137:Vmn1r83 APN 7 12321834 missense probably damaging 1.00
IGL03155:Vmn1r83 APN 7 12321690 missense probably benign
R0627:Vmn1r83 UTSW 7 12321992 missense probably damaging 0.99
R1511:Vmn1r83 UTSW 7 12321270 missense possibly damaging 0.87
R3882:Vmn1r83 UTSW 7 12321402 missense probably damaging 1.00
R4613:Vmn1r83 UTSW 7 12321768 missense probably benign 0.00
R4678:Vmn1r83 UTSW 7 12321770 missense possibly damaging 0.67
R5580:Vmn1r83 UTSW 7 12321873 missense probably benign 0.01
R6982:Vmn1r83 UTSW 7 12321836 missense probably damaging 1.00
R7440:Vmn1r83 UTSW 7 12321629 missense probably damaging 1.00
R7476:Vmn1r83 UTSW 7 12321615 missense possibly damaging 0.93
R7522:Vmn1r83 UTSW 7 12321578 missense possibly damaging 0.61
R7759:Vmn1r83 UTSW 7 12321433 missense probably benign 0.06
Posted On2016-08-02