Incidental Mutation 'IGL03184:Vmn1r68'
ID412393
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r68
Ensembl Gene ENSMUSG00000047031
Gene Namevomeronasal 1 receptor 68
SynonymsGm6898
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL03184
Quality Score
Status
Chromosome7
Chromosomal Location10527210-10528169 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 10527872 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Phenylalanine at position 100 (I100F)
Ref Sequence ENSEMBL: ENSMUSP00000050927 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000058362]
Predicted Effect probably benign
Transcript: ENSMUST00000058362
AA Change: I100F

PolyPhen 2 Score 0.162 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000050927
Gene: ENSMUSG00000047031
AA Change: I100F

DomainStartEndE-ValueType
Pfam:V1R 49 306 2e-33 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 54 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2210408I21Rik T C 13: 77,323,451 Y992H possibly damaging Het
Adcy7 T A 8: 88,308,643 D58E probably benign Het
Aff2 G A X: 69,767,234 V404M possibly damaging Het
Ankhd1 T A 18: 36,647,777 L1961M probably damaging Het
BC024978 A G 7: 27,197,007 probably benign Het
Brms1l T C 12: 55,868,277 *324Q probably null Het
Bub1b T C 2: 118,609,777 probably benign Het
Cacna1b A G 2: 24,658,489 probably null Het
Clrn1 T A 3: 58,846,224 T239S probably benign Het
Clta T C 4: 44,025,514 Y145H probably benign Het
Coro6 T C 11: 77,463,953 V14A probably damaging Het
Cyp4a30b A G 4: 115,459,019 D314G probably damaging Het
Fn1 T C 1: 71,609,497 N1418D probably benign Het
Fshr A C 17: 89,046,640 L97V possibly damaging Het
Gcm2 T C 13: 41,105,412 Q152R probably damaging Het
Gcnt2 A G 13: 40,888,184 N273S probably benign Het
Gm11437 A T 11: 84,156,264 probably benign Het
Gm4559 A G 7: 142,274,309 S19P unknown Het
Igsf8 T G 1: 172,318,632 I462R probably damaging Het
Kirrel3 T C 9: 35,007,756 F243S probably damaging Het
Krt80 C T 15: 101,352,254 V37M probably damaging Het
Lama4 T C 10: 39,078,843 Y1131H probably damaging Het
Mrpl21 T C 19: 3,292,529 probably benign Het
Mtcl1 T C 17: 66,354,214 N923S probably benign Het
Nectin2 G A 7: 19,738,306 P53S possibly damaging Het
Nup98 G A 7: 102,183,545 T335I probably damaging Het
Olfr1247 T C 2: 89,609,568 D178G probably damaging Het
Olfr1391 C A 11: 49,327,741 T110K probably damaging Het
Olfr1507 A G 14: 52,490,923 S14P probably benign Het
Olfr643 T A 7: 104,058,847 I252F probably damaging Het
Olfr822 T C 10: 130,074,758 M116T possibly damaging Het
Pcdhb14 A G 18: 37,449,032 E397G probably benign Het
Pcgf5 T G 19: 36,434,676 probably benign Het
Pclo C T 5: 14,714,443 P1025L probably damaging Het
Pdcd1lg2 C A 19: 29,454,511 F226L probably benign Het
Pik3ca T A 3: 32,439,886 S332R probably benign Het
Plek A T 11: 16,981,887 D321E probably benign Het
Pm20d2 A G 4: 33,179,241 F333L probably damaging Het
Polk T C 13: 96,483,983 T570A probably benign Het
Rpgrip1l G A 8: 91,300,809 L201F probably damaging Het
Serpinb2 T A 1: 107,524,877 L395H probably damaging Het
Slc9c1 T G 16: 45,547,640 S197R probably damaging Het
Smg1 T A 7: 118,180,380 E1264V possibly damaging Het
Sned1 A G 1: 93,274,668 D678G probably benign Het
Sorcs2 A G 5: 36,031,212 S851P probably benign Het
Srcap A G 7: 127,530,502 probably benign Het
Tbck T C 3: 132,736,103 Y557H probably damaging Het
Tfap2d T C 1: 19,118,886 S219P probably damaging Het
Trim9 T C 12: 70,251,221 D570G probably damaging Het
Usp25 A G 16: 77,081,653 Y655C probably damaging Het
Utrn T A 10: 12,710,166 T956S probably benign Het
Vps13a A T 19: 16,654,370 S2634T probably benign Het
Zfp472 T A 17: 32,977,416 L155* probably null Het
Zfp808 A G 13: 62,169,567 I43M possibly damaging Het
Other mutations in Vmn1r68
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01892:Vmn1r68 APN 7 10527407 missense possibly damaging 0.76
IGL02051:Vmn1r68 APN 7 10528021 missense probably benign 0.00
IGL02112:Vmn1r68 APN 7 10527860 missense probably damaging 0.96
IGL02619:Vmn1r68 APN 7 10527676 missense probably benign 0.14
IGL03033:Vmn1r68 APN 7 10528147 missense probably damaging 0.99
PIT4354001:Vmn1r68 UTSW 7 10528031 missense probably benign
R0141:Vmn1r68 UTSW 7 10527325 missense possibly damaging 0.69
R0359:Vmn1r68 UTSW 7 10527274 missense probably damaging 1.00
R0634:Vmn1r68 UTSW 7 10527235 missense probably benign 0.00
R1731:Vmn1r68 UTSW 7 10527875 missense probably damaging 1.00
R2021:Vmn1r68 UTSW 7 10527991 missense probably damaging 1.00
R2022:Vmn1r68 UTSW 7 10527991 missense probably damaging 1.00
R2243:Vmn1r68 UTSW 7 10528162 missense probably damaging 0.98
R2262:Vmn1r68 UTSW 7 10527445 missense probably damaging 1.00
R3877:Vmn1r68 UTSW 7 10527481 missense probably damaging 1.00
R4470:Vmn1r68 UTSW 7 10527348 missense probably benign 0.23
R4843:Vmn1r68 UTSW 7 10527977 missense probably benign 0.00
R5198:Vmn1r68 UTSW 7 10527796 missense probably benign 0.00
R5835:Vmn1r68 UTSW 7 10527820 missense possibly damaging 0.68
R5906:Vmn1r68 UTSW 7 10527623 missense probably benign 0.02
R6015:Vmn1r68 UTSW 7 10527689 missense probably benign 0.31
R7073:Vmn1r68 UTSW 7 10527851 missense probably benign 0.00
R7614:Vmn1r68 UTSW 7 10527626 missense probably benign 0.05
R7699:Vmn1r68 UTSW 7 10527632 missense probably benign 0.15
R7700:Vmn1r68 UTSW 7 10527632 missense probably benign 0.15
R7912:Vmn1r68 UTSW 7 10527310 missense probably benign 0.01
R7993:Vmn1r68 UTSW 7 10527310 missense probably benign 0.01
Posted On2016-08-02