Incidental Mutation 'IGL03190:Vmn1r63'
| ID |
412600 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r63
|
| Ensembl Gene |
ENSMUSG00000058631 |
| Gene Name |
vomeronasal 1 receptor 63 |
| Synonyms |
V1R1, V1rd1 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.049)
|
| Stock # |
IGL03190
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
5805344-5808444 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 5806110 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 174
(D174G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074593
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075085]
|
| AlphaFold |
Q9EPT1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075085
AA Change: D174G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000074593
Gene: ENSMUSG00000058631
AA Change: D174G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
1 |
294 |
3.1e-10 |
PFAM |
|
Pfam:V1R
|
31 |
297 |
2.2e-17 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207420
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 37 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy4 |
A |
T |
14: 56,016,510 (GRCm39) |
C314S |
probably damaging |
Het |
| Agr2 |
T |
A |
12: 36,048,634 (GRCm39) |
I128N |
probably damaging |
Het |
| Akr1c6 |
T |
C |
13: 4,496,412 (GRCm39) |
I91T |
possibly damaging |
Het |
| Ankrd45 |
A |
G |
1: 160,990,909 (GRCm39) |
I221V |
probably benign |
Het |
| Armc3 |
A |
T |
2: 19,293,761 (GRCm39) |
L517F |
probably damaging |
Het |
| Atp13a3 |
A |
T |
16: 30,141,766 (GRCm39) |
M1129K |
probably benign |
Het |
| Atp6v0a4 |
T |
A |
6: 38,031,491 (GRCm39) |
Q670L |
probably benign |
Het |
| Bank1 |
T |
C |
3: 135,806,185 (GRCm39) |
Y483C |
probably damaging |
Het |
| Bcan |
A |
T |
3: 87,900,357 (GRCm39) |
|
probably benign |
Het |
| Bcl11a |
G |
A |
11: 24,108,333 (GRCm39) |
E104K |
probably benign |
Het |
| Clasp2 |
C |
T |
9: 113,673,208 (GRCm39) |
Q368* |
probably null |
Het |
| Clcn1 |
T |
A |
6: 42,267,037 (GRCm39) |
Y71N |
probably benign |
Het |
| Cul2 |
C |
T |
18: 3,429,634 (GRCm39) |
T498I |
possibly damaging |
Het |
| Fat4 |
A |
G |
3: 39,035,390 (GRCm39) |
D3014G |
probably damaging |
Het |
| Flnc |
T |
C |
6: 29,445,636 (GRCm39) |
|
probably benign |
Het |
| Il36g |
C |
A |
2: 24,077,272 (GRCm39) |
S28* |
probably null |
Het |
| Itgb3bp |
A |
G |
4: 99,677,923 (GRCm39) |
|
probably benign |
Het |
| Itm2b |
G |
A |
14: 73,603,229 (GRCm39) |
P120L |
probably damaging |
Het |
| Klk1b26 |
T |
C |
7: 43,662,151 (GRCm39) |
F3S |
possibly damaging |
Het |
| Lin52 |
T |
C |
12: 84,504,732 (GRCm39) |
V39A |
probably damaging |
Het |
| Magt1 |
A |
C |
X: 105,032,622 (GRCm39) |
N242K |
probably benign |
Het |
| Nos3 |
A |
G |
5: 24,588,627 (GRCm39) |
M1118V |
probably damaging |
Het |
| Or1j13 |
A |
T |
2: 36,369,734 (GRCm39) |
M136K |
probably damaging |
Het |
| Or6k2 |
T |
C |
1: 173,987,110 (GRCm39) |
V257A |
probably damaging |
Het |
| Paqr5 |
A |
C |
9: 61,880,084 (GRCm39) |
L56R |
probably damaging |
Het |
| Pcdhb16 |
T |
C |
18: 37,612,396 (GRCm39) |
F452S |
probably damaging |
Het |
| Prdm5 |
T |
A |
6: 65,833,116 (GRCm39) |
|
probably benign |
Het |
| Rps6ka5 |
A |
G |
12: 100,524,907 (GRCm39) |
|
probably benign |
Het |
| Slc22a5 |
A |
G |
11: 53,765,840 (GRCm39) |
F249L |
probably benign |
Het |
| Spata31f1a |
C |
A |
4: 42,848,362 (GRCm39) |
G1265C |
probably benign |
Het |
| Ttll2 |
T |
C |
17: 7,618,779 (GRCm39) |
K383E |
probably benign |
Het |
| Ube2o |
G |
A |
11: 116,435,954 (GRCm39) |
P353L |
probably damaging |
Het |
| Vmn2r82 |
A |
G |
10: 79,192,643 (GRCm39) |
|
probably null |
Het |
| Xpnpep2 |
T |
A |
X: 47,207,205 (GRCm39) |
|
probably benign |
Het |
| Zfp352 |
T |
A |
4: 90,111,994 (GRCm39) |
S45T |
possibly damaging |
Het |
| Zfp811 |
A |
G |
17: 33,017,855 (GRCm39) |
|
probably benign |
Het |
| Zfyve19 |
G |
A |
2: 119,046,717 (GRCm39) |
A304T |
probably damaging |
Het |
|
| Other mutations in Vmn1r63 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02465:Vmn1r63
|
APN |
7 |
5,806,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02897:Vmn1r63
|
APN |
7 |
5,805,744 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03032:Vmn1r63
|
APN |
7 |
5,806,350 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0118:Vmn1r63
|
UTSW |
7 |
5,805,838 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0227:Vmn1r63
|
UTSW |
7 |
5,805,741 (GRCm39) |
nonsense |
probably null |
|
|
R0323:Vmn1r63
|
UTSW |
7 |
5,806,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0610:Vmn1r63
|
UTSW |
7 |
5,806,063 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0630:Vmn1r63
|
UTSW |
7 |
5,806,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0689:Vmn1r63
|
UTSW |
7 |
5,806,609 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1916:Vmn1r63
|
UTSW |
7 |
5,806,225 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1993:Vmn1r63
|
UTSW |
7 |
5,806,254 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1994:Vmn1r63
|
UTSW |
7 |
5,806,254 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2209:Vmn1r63
|
UTSW |
7 |
5,806,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3787:Vmn1r63
|
UTSW |
7 |
5,805,751 (GRCm39) |
missense |
probably benign |
|
|
R4156:Vmn1r63
|
UTSW |
7 |
5,806,531 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4702:Vmn1r63
|
UTSW |
7 |
5,806,516 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4728:Vmn1r63
|
UTSW |
7 |
5,806,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5410:Vmn1r63
|
UTSW |
7 |
5,806,189 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5796:Vmn1r63
|
UTSW |
7 |
5,806,140 (GRCm39) |
missense |
probably benign |
|
|
R6580:Vmn1r63
|
UTSW |
7 |
5,805,913 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6723:Vmn1r63
|
UTSW |
7 |
5,805,948 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7418:Vmn1r63
|
UTSW |
7 |
5,806,554 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7476:Vmn1r63
|
UTSW |
7 |
5,806,000 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7769:Vmn1r63
|
UTSW |
7 |
5,806,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8912:Vmn1r63
|
UTSW |
7 |
5,806,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9684:Vmn1r63
|
UTSW |
7 |
5,805,913 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0027:Vmn1r63
|
UTSW |
7 |
5,805,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2016-08-02 |
Incidental Mutation