Incidental Mutation 'IGL03202:Lce1l'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lce1l
Ensembl Gene ENSMUSG00000046676
Gene Namelate cornified envelope 1L
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.081) question?
Stock #IGL03202
Quality Score
Chromosomal Location92849949-92851286 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 92850324 bp
Amino Acid Change Cysteine to Serine at position 76 (C76S)
Ref Sequence ENSEMBL: ENSMUSP00000057762 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000054426]
Predicted Effect unknown
Transcript: ENSMUST00000054426
AA Change: C76S
SMART Domains Protein: ENSMUSP00000057762
Gene: ENSMUSG00000046676
AA Change: C76S

Pfam:LCE 25 67 1.6e-12 PFAM
Pfam:LCE 65 135 2.5e-9 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700113H08Rik T C 10: 87,074,047 M1T probably null Het
2810474O19Rik G A 6: 149,326,439 V328I probably benign Het
Ace T A 11: 105,976,962 I168N probably damaging Het
Actr10 T G 12: 70,940,831 C37W probably damaging Het
Atp10b T C 11: 43,234,441 probably null Het
Bend5 A G 4: 111,433,244 N146D possibly damaging Het
Cacna1b A G 2: 24,651,112 F1347L probably damaging Het
Crybg3 T A 16: 59,494,709 I2910F probably damaging Het
Cspg4 T C 9: 56,897,739 S1945P possibly damaging Het
Cxcr4 T G 1: 128,588,904 K340T probably damaging Het
Dnah6 T A 6: 73,144,700 Y1433F probably damaging Het
Eif2ak4 T C 2: 118,400,620 V77A probably damaging Het
Fscn3 A T 6: 28,434,452 H342L probably benign Het
Gm884 T A 11: 103,615,373 E1923V probably benign Het
Gm9843 T C 16: 76,403,346 noncoding transcript Het
Hdac9 T C 12: 34,373,951 E520G probably damaging Het
Itm2b G A 14: 73,365,789 P120L probably damaging Het
Itpa T A 2: 130,667,939 probably benign Het
Lin54 A G 5: 100,475,814 S55P possibly damaging Het
Mtfmt C A 9: 65,448,726 P303Q probably damaging Het
Nae1 A T 8: 104,518,179 probably benign Het
Ncapd3 T A 9: 27,071,715 probably benign Het
Olfr381 G A 11: 73,486,525 Q100* probably null Het
Olfr525 A G 7: 140,323,106 M136V possibly damaging Het
Pcnx2 A C 8: 125,772,044 I1572S probably damaging Het
Piezo2 A T 18: 63,011,598 Y2809N probably damaging Het
Pygl G T 12: 70,199,646 Q376K probably benign Het
Rrp12 T C 19: 41,868,766 probably null Het
Sephs1 A T 2: 4,889,263 I92F possibly damaging Het
Taar4 T C 10: 23,960,794 F101L probably damaging Het
Tenm2 A G 11: 36,024,548 I2053T probably damaging Het
Tgfbr3 T G 5: 107,109,764 probably benign Het
Vmn2r108 A T 17: 20,471,057 Y401* probably null Het
Vmn2r87 A G 10: 130,497,222 M53T probably benign Het
Zfp941 A G 7: 140,813,053 V131A probably benign Het
Other mutations in Lce1l
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1724:Lce1l UTSW 3 92850419 missense unknown
R4075:Lce1l UTSW 3 92850233 missense unknown
R4515:Lce1l UTSW 3 92850474 missense unknown
R5531:Lce1l UTSW 3 92850497 missense unknown
R6785:Lce1l UTSW 3 92850193 nonsense probably null
R7298:Lce1l UTSW 3 92850176 missense unknown
R8310:Lce1l UTSW 3 92850459 missense unknown
R8312:Lce1l UTSW 3 92850459 missense unknown
Posted On2016-08-02