Incidental Mutation 'IGL03206:Retnlg'
ID413136
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Retnlg
Ensembl Gene ENSMUSG00000022651
Gene Nameresistin like gamma
SynonymsFizz3, Relmg, Xcp1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL03206
Quality Score
Status
Chromosome16
Chromosomal Location48872621-48874496 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 48874292 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Phenylalanine at position 101 (C101F)
Ref Sequence ENSEMBL: ENSMUSP00000070238 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000065666]
Predicted Effect probably damaging
Transcript: ENSMUST00000065666
AA Change: C101F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000070238
Gene: ENSMUSG00000022651
AA Change: C101F

DomainStartEndE-ValueType
low complexity region 9 21 N/A INTRINSIC
Pfam:Resistin 29 116 1.6e-38 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A2ml1 T A 6: 128,553,276 E939D possibly damaging Het
Aloxe3 C A 11: 69,129,646 A172D possibly damaging Het
Bscl2 G A 19: 8,843,089 R158Q probably damaging Het
Cdon A G 9: 35,503,306 D1159G probably benign Het
Cep164 A G 9: 45,802,725 V203A probably benign Het
Chml T C 1: 175,687,737 D206G probably benign Het
E2f6 T C 12: 16,822,089 probably benign Het
Emilin3 T A 2: 160,910,799 Y77F probably damaging Het
Fbxw15 A T 9: 109,565,362 N128K possibly damaging Het
Gjd2 A G 2: 114,011,723 L91P probably damaging Het
Gm12830 T A 4: 114,845,117 probably benign Het
Gpr161 T A 1: 165,321,649 L529Q probably damaging Het
Hoxd10 T A 2: 74,692,432 Y151* probably null Het
Iars A G 13: 49,693,070 D215G possibly damaging Het
Ift140 T C 17: 25,092,826 V1241A probably damaging Het
Kdm5b A G 1: 134,627,317 N1321S probably benign Het
Lrat T A 3: 82,903,349 I122F probably damaging Het
Myl10 C T 5: 136,697,942 Q106* probably null Het
Ncapd2 A T 6: 125,171,697 Y1018N possibly damaging Het
Ndrg1 C T 15: 66,943,087 W172* probably null Het
Nphs2 T C 1: 156,326,131 M264T probably damaging Het
Nrxn3 A T 12: 89,260,508 R677S possibly damaging Het
Nudt12 T C 17: 59,007,672 T306A probably benign Het
Numb A G 12: 83,825,296 probably benign Het
Olfr1385 A T 11: 49,494,709 M59L probably benign Het
Olfr482 C T 7: 108,095,054 C172Y probably damaging Het
Olfr63 T A 17: 33,268,751 I9K possibly damaging Het
Pbld2 T A 10: 63,047,482 D94E probably benign Het
Pkd1l3 C A 8: 109,623,713 Q397K probably benign Het
Ppp4r3a A T 12: 101,058,619 L207H probably damaging Het
Ranbp2 T A 10: 58,465,547 I674N probably damaging Het
Rif1 T A 2: 52,103,622 I849N probably damaging Het
Serpinb9d T C 13: 33,198,031 I161T possibly damaging Het
Slc17a6 T C 7: 51,666,023 probably benign Het
Smg8 A C 11: 87,085,988 probably null Het
Spata31d1c C A 13: 65,035,593 N316K probably benign Het
Tlr1 A G 5: 64,925,057 S726P probably damaging Het
Trim69 A C 2: 122,173,155 D195A probably benign Het
Ttc16 T G 2: 32,771,885 probably null Het
Usp53 T A 3: 122,953,183 M405L probably benign Het
Ywhag G A 5: 135,911,060 R227* probably null Het
Zfp335 G T 2: 164,892,681 probably benign Het
Zfp607a T C 7: 27,877,823 I106T possibly damaging Het
Zfp959 T C 17: 55,897,613 S214P possibly damaging Het
Zfyve9 T C 4: 108,689,209 M868V possibly damaging Het
Other mutations in Retnlg
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00985:Retnlg APN 16 48874325 missense possibly damaging 0.89
IGL02500:Retnlg APN 16 48872960 missense probably benign 0.16
IGL02588:Retnlg APN 16 48872892 missense probably benign 0.07
R1165:Retnlg UTSW 16 48873654 missense possibly damaging 0.76
R1751:Retnlg UTSW 16 48873628 missense possibly damaging 0.54
R1767:Retnlg UTSW 16 48873628 missense possibly damaging 0.54
R1796:Retnlg UTSW 16 48874247 missense probably benign 0.06
R2037:Retnlg UTSW 16 48874252 missense probably damaging 1.00
R4780:Retnlg UTSW 16 48874334 missense possibly damaging 0.74
R7298:Retnlg UTSW 16 48872874 missense probably benign
Posted On2016-08-02