Incidental Mutation 'IGL03211:Slc38a2'
ID413316
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc38a2
Ensembl Gene ENSMUSG00000022462
Gene Namesolute carrier family 38, member 2
Synonyms5033402L14Rik
Accession Numbers

NCBI RefSeq: NM_175121.3; MGI:1915010

Is this an essential gene? Possibly non essential (E-score: 0.368) question?
Stock #IGL03211
Quality Score
Status
Chromosome15
Chromosomal Location96687392-96699730 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 96698272 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000023099 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000023099]
Predicted Effect probably null
Transcript: ENSMUST00000023099
SMART Domains Protein: ENSMUSP00000023099
Gene: ENSMUSG00000022462

DomainStartEndE-ValueType
low complexity region 10 30 N/A INTRINSIC
Pfam:Aa_trans 69 492 2e-76 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000192790
Predicted Effect noncoding transcript
Transcript: ENSMUST00000229141
Coding Region Coverage
Validation Efficiency
Allele List at MGI

All alleles(18) : Targeted(2) Gene trapped(16)

Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Bmp7 C T 2: 172,872,883 V378I possibly damaging Het
Cd209b G T 8: 3,918,830 probably benign Het
Cilp A T 9: 65,280,175 Q1184L probably benign Het
Cysltr2 A T 14: 73,029,715 M185K possibly damaging Het
Dcaf6 A G 1: 165,422,933 F121L possibly damaging Het
Dnajc8 T A 4: 132,544,737 Y95N possibly damaging Het
Ebf3 A G 7: 137,231,304 V214A probably benign Het
Elavl3 A G 9: 22,018,678 V310A probably damaging Het
Emc2 C T 15: 43,507,672 R131* probably null Het
Hcn4 G A 9: 58,858,151 V639M unknown Het
Kif21a T G 15: 90,997,963 D46A possibly damaging Het
Kitl T C 10: 100,080,859 S175P probably benign Het
Klhl32 C T 4: 24,792,616 probably null Het
Plcg1 C T 2: 160,759,691 T972I possibly damaging Het
Prdm13 T C 4: 21,678,492 H666R probably damaging Het
Rap1gap G A 4: 137,715,846 probably null Het
Rdh7 T C 10: 127,887,623 N121S probably benign Het
Ric8b T A 10: 85,001,793 I488N probably damaging Het
Slc9a9 G A 9: 95,137,990 probably benign Het
Tk2 T A 8: 104,243,441 I64F probably damaging Het
Virma G A 4: 11,548,770 W1776* probably null Het
Vrk1 C T 12: 106,036,588 A15V probably benign Het
Wdfy3 T C 5: 101,844,912 probably benign Het
Wfdc10 T C 2: 164,657,252 V94A probably benign Het
Zfp780b A T 7: 27,963,175 C652S possibly damaging Het
Other mutations in Slc38a2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01116:Slc38a2 APN 15 96693185 splice site probably benign
IGL01522:Slc38a2 APN 15 96693055 missense possibly damaging 0.78
IGL01679:Slc38a2 APN 15 96697954 nonsense probably null
IGL01720:Slc38a2 APN 15 96691211 splice site probably benign
IGL02198:Slc38a2 APN 15 96692377 missense probably damaging 0.99
IGL02685:Slc38a2 APN 15 96691425 missense probably benign 0.00
P0014:Slc38a2 UTSW 15 96690161 missense probably damaging 0.96
R0068:Slc38a2 UTSW 15 96691292 splice site probably null
R0068:Slc38a2 UTSW 15 96691292 splice site probably null
R0684:Slc38a2 UTSW 15 96695287 nonsense probably null
R1537:Slc38a2 UTSW 15 96693153 missense possibly damaging 0.50
R1638:Slc38a2 UTSW 15 96692536 missense probably damaging 1.00
R1922:Slc38a2 UTSW 15 96691162 missense possibly damaging 0.95
R2294:Slc38a2 UTSW 15 96691762 missense probably benign
R4672:Slc38a2 UTSW 15 96698637 missense probably benign 0.00
R5799:Slc38a2 UTSW 15 96695089 missense probably benign 0.29
R5878:Slc38a2 UTSW 15 96692584 missense probably damaging 0.96
R6188:Slc38a2 UTSW 15 96692516 critical splice donor site probably null
R7097:Slc38a2 UTSW 15 96693301 missense probably damaging 0.98
R7122:Slc38a2 UTSW 15 96693301 missense probably damaging 0.98
R7130:Slc38a2 UTSW 15 96691382 missense probably damaging 1.00
R7224:Slc38a2 UTSW 15 96691359 missense probably damaging 1.00
R7776:Slc38a2 UTSW 15 96690152 missense probably benign 0.04
R7896:Slc38a2 UTSW 15 96693585 missense probably damaging 1.00
R7964:Slc38a2 UTSW 15 96692572 missense probably benign 0.29
Posted On2016-08-02