Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03213:Vmn2r17'

413396

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r17

Ensembl Gene

ENSMUSG00000091879

Gene Name

vomeronasal 2, receptor 17

Synonyms

EG384221

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

IGL03213

Quality Score

Status

Chromosome

Chromosomal Location

109420013-109453387 bp(+) (GRCm38)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

T to C at 109434390 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000131450 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171841]

AlphaFold

E9PYF5

Predicted Effect

probably null
Transcript: ENSMUST00000171841

SMART Domains

Protein: ENSMUSP00000131450
Gene: ENSMUSG00000091879

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:ANF_receptor	76	465	7e-26	PFAM
Pfam:NCD3G	508	562	3.5e-18	PFAM
Pfam:7tm_3	593	830	4.8e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abi1	A	T	2: 22,941,959	D447E	probably damaging	Het
Aldh8a1	T	C	10: 21,384,717	V175A	probably damaging	Het
Arap2	T	A	5: 62,749,095	T194S	probably benign	Het
Arih2	T	C	9: 108,607,347	T422A	probably damaging	Het
Arl5b	T	A	2: 15,069,865	N52K	probably damaging	Het
Atg13	G	A	2: 91,685,167	H227Y	probably damaging	Het
Ccdc178	T	C	18: 22,120,691	T164A	possibly damaging	Het
Cep192	T	C	18: 67,865,637	V2074A	probably damaging	Het
Ces2c	T	C	8: 104,848,040	I43T	probably benign	Het
Chrm3	G	A	13: 9,878,184	T272I	probably benign	Het
Cln8	A	G	8: 14,894,845	Y53C	probably damaging	Het
Cwc27	T	A	13: 104,796,403		probably benign	Het
Cyp3a13	A	T	5: 137,894,267		probably benign	Het
Dchs1	G	T	7: 105,755,072	N2754K	probably damaging	Het
Dclk1	A	T	3: 55,480,384	K84*	probably null	Het
Ednra	T	C	8: 77,720,219	T77A	probably benign	Het
Epn2	T	C	11: 61,519,684	N553D	probably damaging	Het
Fut2	C	T	7: 45,650,769	G193E	possibly damaging	Het
Gm10784	T	A	13: 49,945,274		noncoding transcript	Het
Gm11492	G	T	11: 87,567,358		probably null	Het
Gm9047	G	A	6: 29,471,793	M89I	probably damaging	Het
Gtf2e2	T	C	8: 33,752,497	F76L	probably damaging	Het
Hnrnpll	A	T	17: 80,034,098	V504E	probably damaging	Het
Ifitm2	A	G	7: 140,955,764	V51A	possibly damaging	Het
Il16	C	T	7: 83,646,500	E456K	probably damaging	Het
Lmod2	A	T	6: 24,603,616	I197F	possibly damaging	Het
Lrrc14	T	C	15: 76,713,783	S238P	possibly damaging	Het
Map3k1	A	G	13: 111,748,892		probably benign	Het
Phf11d	C	A	14: 59,349,348	R210S	probably benign	Het
Pigu	T	C	2: 155,335,371	N103S	probably damaging	Het
Rgsl1	A	G	1: 153,825,841	V289A	probably benign	Het
Rp1l1	T	A	14: 64,028,415	S483R	probably damaging	Het
Ryr2	A	T	13: 11,724,387		probably benign	Het
Sema3c	T	G	5: 17,694,639		probably benign	Het
Sfmbt2	A	G	2: 10,404,574	Y110C	probably damaging	Het
Slc12a3	T	C	8: 94,335,305	V328A	possibly damaging	Het
Smarca2	G	A	19: 26,623,975	G31D	probably damaging	Het
Svs1	A	G	6: 48,988,345	D429G	possibly damaging	Het
Tenm2	T	G	11: 36,023,330	E2460A	probably benign	Het
Trim58	T	A	11: 58,651,167	W318R	probably benign	Het
Ube3a	C	T	7: 59,286,122	Q585*	probably null	Het
Zfp647	A	G	15: 76,911,977	V161A	possibly damaging	Het

Other mutations in Vmn2r17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00325:Vmn2r17	APN	5	109427992	missense	probably benign	0.15
IGL01457:Vmn2r17	APN	5	109453032	missense	probably benign	0.00
IGL01527:Vmn2r17	APN	5	109453140	missense	probably damaging	1.00
IGL01693:Vmn2r17	APN	5	109452518	missense	probably damaging	1.00
IGL01738:Vmn2r17	APN	5	109429498	missense	probably damaging	1.00
IGL01767:Vmn2r17	APN	5	109420037	missense	probably benign	0.01
IGL01932:Vmn2r17	APN	5	109427050	missense	probably benign	0.00
IGL01970:Vmn2r17	APN	5	109427947	missense	probably damaging	0.97
IGL02009:Vmn2r17	APN	5	109452848	missense	possibly damaging	0.67
IGL02365:Vmn2r17	APN	5	109453309	missense	probably damaging	1.00
IGL02385:Vmn2r17	APN	5	109434381	missense	probably damaging	1.00
IGL02457:Vmn2r17	APN	5	109453146	missense	probably damaging	1.00
IGL02646:Vmn2r17	APN	5	109453080	missense	probably damaging	1.00
IGL02741:Vmn2r17	APN	5	109420211	missense	probably benign
IGL03216:Vmn2r17	APN	5	109452890	missense	probably damaging	1.00
IGL03342:Vmn2r17	APN	5	109427916	missense	probably damaging	1.00
IGL03408:Vmn2r17	APN	5	109429372	splice site	probably benign
R0349:Vmn2r17	UTSW	5	109428336	missense	probably damaging	1.00
R0418:Vmn2r17	UTSW	5	109452881	missense	probably damaging	1.00
R0800:Vmn2r17	UTSW	5	109427326	splice site	probably benign
R0836:Vmn2r17	UTSW	5	109427956	missense	possibly damaging	0.89
R1715:Vmn2r17	UTSW	5	109428244	missense	probably benign	0.00
R1738:Vmn2r17	UTSW	5	109428511	missense	probably benign	0.10
R1801:Vmn2r17	UTSW	5	109428478	missense	probably damaging	1.00
R2054:Vmn2r17	UTSW	5	109452486	missense	probably damaging	0.98
R2060:Vmn2r17	UTSW	5	109427209	missense	probably benign	0.00
R2192:Vmn2r17	UTSW	5	109434278	missense	possibly damaging	0.81
R2315:Vmn2r17	UTSW	5	109428031	missense	probably damaging	1.00
R2374:Vmn2r17	UTSW	5	109427238	missense	probably benign
R3612:Vmn2r17	UTSW	5	109429597	missense	probably benign	0.00
R3832:Vmn2r17	UTSW	5	109428396	missense	probably damaging	1.00
R4273:Vmn2r17	UTSW	5	109452966	missense	probably benign	0.44
R4494:Vmn2r17	UTSW	5	109428469	missense	probably damaging	1.00
R4597:Vmn2r17	UTSW	5	109429562	missense	probably benign	0.01
R4675:Vmn2r17	UTSW	5	109427183	missense	probably benign	0.00
R4701:Vmn2r17	UTSW	5	109427983	missense	probably damaging	0.99
R4754:Vmn2r17	UTSW	5	109452849	missense	probably damaging	0.99
R4841:Vmn2r17	UTSW	5	109434380	missense	probably damaging	1.00
R4842:Vmn2r17	UTSW	5	109434380	missense	probably damaging	1.00
R4865:Vmn2r17	UTSW	5	109427119	missense	probably damaging	1.00
R4902:Vmn2r17	UTSW	5	109453354	missense	probably benign	0.14
R4989:Vmn2r17	UTSW	5	109427873	missense	probably benign	0.07
R5101:Vmn2r17	UTSW	5	109428351	missense	probably damaging	0.99
R5109:Vmn2r17	UTSW	5	109429476	missense	probably benign	0.06
R5123:Vmn2r17	UTSW	5	109427908	missense	possibly damaging	0.90
R5474:Vmn2r17	UTSW	5	109434284	missense	probably damaging	1.00
R5485:Vmn2r17	UTSW	5	109420106	missense	probably benign	0.06
R5611:Vmn2r17	UTSW	5	109428164	missense	probably damaging	0.97
R5652:Vmn2r17	UTSW	5	109429564	missense	probably benign	0.10
R5717:Vmn2r17	UTSW	5	109427274	missense	possibly damaging	0.94
R5735:Vmn2r17	UTSW	5	109452850	missense	possibly damaging	0.67
R5766:Vmn2r17	UTSW	5	109427273	missense	possibly damaging	0.46
R6645:Vmn2r17	UTSW	5	109428381	missense	probably damaging	1.00
R6786:Vmn2r17	UTSW	5	109427829	missense	probably benign	0.30
R6821:Vmn2r17	UTSW	5	109429465	missense	probably damaging	1.00
R6979:Vmn2r17	UTSW	5	109428399	missense	possibly damaging	0.46
R6984:Vmn2r17	UTSW	5	109452667	missense	probably benign	0.10
R7269:Vmn2r17	UTSW	5	109428471	missense	possibly damaging	0.88
R7509:Vmn2r17	UTSW	5	109427829	missense	probably benign	0.30
R7736:Vmn2r17	UTSW	5	109452891	missense	probably benign	0.05
R7789:Vmn2r17	UTSW	5	109452965	missense	possibly damaging	0.77
R7814:Vmn2r17	UTSW	5	109427873	missense	probably benign	0.07
R7847:Vmn2r17	UTSW	5	109420197	missense	probably damaging	1.00
R7863:Vmn2r17	UTSW	5	109420169	missense	probably benign
R7893:Vmn2r17	UTSW	5	109428078	missense	probably benign	0.05
R8234:Vmn2r17	UTSW	5	109453369	missense	probably benign	0.01
R8382:Vmn2r17	UTSW	5	109428521	missense	probably benign	0.01
R8435:Vmn2r17	UTSW	5	109428306	missense	probably benign	0.01
R8465:Vmn2r17	UTSW	5	109452825	missense	probably damaging	0.99
R8555:Vmn2r17	UTSW	5	109452944	missense	probably damaging	0.99
R8900:Vmn2r17	UTSW	5	109427997	missense	probably benign	0.25
R9293:Vmn2r17	UTSW	5	109452846	missense	probably damaging	1.00
R9308:Vmn2r17	UTSW	5	109452639	missense	probably damaging	0.98
R9378:Vmn2r17	UTSW	5	109427866	missense	possibly damaging	0.94
R9597:Vmn2r17	UTSW	5	109427803	missense	probably damaging	1.00

Posted On

2016-08-02