Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03213:Vmn2r17'

413396

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r17

Ensembl Gene

ENSMUSG00000091879

Gene Name

vomeronasal 2, receptor 17

Synonyms

EG384221

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.092) question?

Stock #

IGL03213

Quality Score

Status

Chromosome

Chromosomal Location

109567879-109601253 bp(+) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

T to C at 109582256 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000131450 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171841]

AlphaFold

E9PYF5

Predicted Effect

probably null
Transcript: ENSMUST00000171841

SMART Domains

Protein: ENSMUSP00000131450
Gene: ENSMUSG00000091879

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:ANF_receptor	76	465	7e-26	PFAM
Pfam:NCD3G	508	562	3.5e-18	PFAM
Pfam:7tm_3	593	830	4.8e-55	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abi1	A	T	2: 22,831,971 (GRCm39)	D447E	probably damaging	Het
Aldh8a1	T	C	10: 21,260,616 (GRCm39)	V175A	probably damaging	Het
Aoc1l3	A	G	6: 48,965,279 (GRCm39)	D429G	possibly damaging	Het
Arap2	T	A	5: 62,906,438 (GRCm39)	T194S	probably benign	Het
Arih2	T	C	9: 108,484,546 (GRCm39)	T422A	probably damaging	Het
Arl5b	T	A	2: 15,074,676 (GRCm39)	N52K	probably damaging	Het
Atg13	G	A	2: 91,515,512 (GRCm39)	H227Y	probably damaging	Het
Ccdc178	T	C	18: 22,253,748 (GRCm39)	T164A	possibly damaging	Het
Cep192	T	C	18: 67,998,708 (GRCm39)	V2074A	probably damaging	Het
Ces2c	T	C	8: 105,574,672 (GRCm39)	I43T	probably benign	Het
Chrm3	G	A	13: 9,928,220 (GRCm39)	T272I	probably benign	Het
Cln8	A	G	8: 14,944,845 (GRCm39)	Y53C	probably damaging	Het
Cwc27	T	A	13: 104,932,911 (GRCm39)		probably benign	Het
Cyp3a13	A	T	5: 137,892,529 (GRCm39)		probably benign	Het
Dchs1	G	T	7: 105,404,279 (GRCm39)	N2754K	probably damaging	Het
Dclk1	A	T	3: 55,387,805 (GRCm39)	K84*	probably null	Het
Ednra	T	C	8: 78,446,848 (GRCm39)	T77A	probably benign	Het
Epn2	T	C	11: 61,410,510 (GRCm39)	N553D	probably damaging	Het
Fut2	C	T	7: 45,300,193 (GRCm39)	G193E	possibly damaging	Het
Gm10784	T	A	13: 50,099,310 (GRCm39)		noncoding transcript	Het
Gtf2e2	T	C	8: 34,242,525 (GRCm39)	F76L	probably damaging	Het
Hnrnpll	A	T	17: 80,341,527 (GRCm39)	V504E	probably damaging	Het
Ifitm2	A	G	7: 140,535,677 (GRCm39)	V51A	possibly damaging	Het
Il16	C	T	7: 83,295,708 (GRCm39)	E456K	probably damaging	Het
Lmod2	A	T	6: 24,603,615 (GRCm39)	I197F	possibly damaging	Het
Lrrc14	T	C	15: 76,597,983 (GRCm39)	S238P	possibly damaging	Het
Map3k1	A	G	13: 111,885,426 (GRCm39)		probably benign	Het
Phf11d	C	A	14: 59,586,797 (GRCm39)	R210S	probably benign	Het
Pigu	T	C	2: 155,177,291 (GRCm39)	N103S	probably damaging	Het
Rgsl1	A	G	1: 153,701,587 (GRCm39)	V289A	probably benign	Het
Rp1l1	T	A	14: 64,265,864 (GRCm39)	S483R	probably damaging	Het
Ryr2	A	T	13: 11,739,273 (GRCm39)		probably benign	Het
Sema3c	T	G	5: 17,899,637 (GRCm39)		probably benign	Het
Septin4	G	T	11: 87,458,184 (GRCm39)		probably null	Het
Sfmbt2	A	G	2: 10,409,385 (GRCm39)	Y110C	probably damaging	Het
Slc12a3	T	C	8: 95,061,933 (GRCm39)	V328A	possibly damaging	Het
Smarca2	G	A	19: 26,601,375 (GRCm39)	G31D	probably damaging	Het
Spmip1	G	A	6: 29,471,792 (GRCm39)	M89I	probably damaging	Het
Tenm2	T	G	11: 35,914,157 (GRCm39)	E2460A	probably benign	Het
Trim58	T	A	11: 58,541,993 (GRCm39)	W318R	probably benign	Het
Ube3a	C	T	7: 58,935,870 (GRCm39)	Q585*	probably null	Het
Zfp647	A	G	15: 76,796,177 (GRCm39)	V161A	possibly damaging	Het

Other mutations in Vmn2r17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00325:Vmn2r17	APN	5	109,575,858 (GRCm39)	missense	probably benign	0.15
IGL01457:Vmn2r17	APN	5	109,600,898 (GRCm39)	missense	probably benign	0.00
IGL01527:Vmn2r17	APN	5	109,601,006 (GRCm39)	missense	probably damaging	1.00
IGL01693:Vmn2r17	APN	5	109,600,384 (GRCm39)	missense	probably damaging	1.00
IGL01738:Vmn2r17	APN	5	109,577,364 (GRCm39)	missense	probably damaging	1.00
IGL01767:Vmn2r17	APN	5	109,567,903 (GRCm39)	missense	probably benign	0.01
IGL01932:Vmn2r17	APN	5	109,574,916 (GRCm39)	missense	probably benign	0.00
IGL01970:Vmn2r17	APN	5	109,575,813 (GRCm39)	missense	probably damaging	0.97
IGL02009:Vmn2r17	APN	5	109,600,714 (GRCm39)	missense	possibly damaging	0.67
IGL02365:Vmn2r17	APN	5	109,601,175 (GRCm39)	missense	probably damaging	1.00
IGL02385:Vmn2r17	APN	5	109,582,247 (GRCm39)	missense	probably damaging	1.00
IGL02457:Vmn2r17	APN	5	109,601,012 (GRCm39)	missense	probably damaging	1.00
IGL02646:Vmn2r17	APN	5	109,600,946 (GRCm39)	missense	probably damaging	1.00
IGL02741:Vmn2r17	APN	5	109,568,077 (GRCm39)	missense	probably benign
IGL03216:Vmn2r17	APN	5	109,600,756 (GRCm39)	missense	probably damaging	1.00
IGL03342:Vmn2r17	APN	5	109,575,782 (GRCm39)	missense	probably damaging	1.00
IGL03408:Vmn2r17	APN	5	109,577,238 (GRCm39)	splice site	probably benign
R0349:Vmn2r17	UTSW	5	109,576,202 (GRCm39)	missense	probably damaging	1.00
R0418:Vmn2r17	UTSW	5	109,600,747 (GRCm39)	missense	probably damaging	1.00
R0800:Vmn2r17	UTSW	5	109,575,192 (GRCm39)	splice site	probably benign
R0836:Vmn2r17	UTSW	5	109,575,822 (GRCm39)	missense	possibly damaging	0.89
R1715:Vmn2r17	UTSW	5	109,576,110 (GRCm39)	missense	probably benign	0.00
R1738:Vmn2r17	UTSW	5	109,576,377 (GRCm39)	missense	probably benign	0.10
R1801:Vmn2r17	UTSW	5	109,576,344 (GRCm39)	missense	probably damaging	1.00
R2054:Vmn2r17	UTSW	5	109,600,352 (GRCm39)	missense	probably damaging	0.98
R2060:Vmn2r17	UTSW	5	109,575,075 (GRCm39)	missense	probably benign	0.00
R2192:Vmn2r17	UTSW	5	109,582,144 (GRCm39)	missense	possibly damaging	0.81
R2315:Vmn2r17	UTSW	5	109,575,897 (GRCm39)	missense	probably damaging	1.00
R2374:Vmn2r17	UTSW	5	109,575,104 (GRCm39)	missense	probably benign
R3612:Vmn2r17	UTSW	5	109,577,463 (GRCm39)	missense	probably benign	0.00
R3832:Vmn2r17	UTSW	5	109,576,262 (GRCm39)	missense	probably damaging	1.00
R4273:Vmn2r17	UTSW	5	109,600,832 (GRCm39)	missense	probably benign	0.44
R4494:Vmn2r17	UTSW	5	109,576,335 (GRCm39)	missense	probably damaging	1.00
R4597:Vmn2r17	UTSW	5	109,577,428 (GRCm39)	missense	probably benign	0.01
R4675:Vmn2r17	UTSW	5	109,575,049 (GRCm39)	missense	probably benign	0.00
R4701:Vmn2r17	UTSW	5	109,575,849 (GRCm39)	missense	probably damaging	0.99
R4754:Vmn2r17	UTSW	5	109,600,715 (GRCm39)	missense	probably damaging	0.99
R4841:Vmn2r17	UTSW	5	109,582,246 (GRCm39)	missense	probably damaging	1.00
R4842:Vmn2r17	UTSW	5	109,582,246 (GRCm39)	missense	probably damaging	1.00
R4865:Vmn2r17	UTSW	5	109,574,985 (GRCm39)	missense	probably damaging	1.00
R4902:Vmn2r17	UTSW	5	109,601,220 (GRCm39)	missense	probably benign	0.14
R4989:Vmn2r17	UTSW	5	109,575,739 (GRCm39)	missense	probably benign	0.07
R5101:Vmn2r17	UTSW	5	109,576,217 (GRCm39)	missense	probably damaging	0.99
R5109:Vmn2r17	UTSW	5	109,577,342 (GRCm39)	missense	probably benign	0.06
R5123:Vmn2r17	UTSW	5	109,575,774 (GRCm39)	missense	possibly damaging	0.90
R5474:Vmn2r17	UTSW	5	109,582,150 (GRCm39)	missense	probably damaging	1.00
R5485:Vmn2r17	UTSW	5	109,567,972 (GRCm39)	missense	probably benign	0.06
R5611:Vmn2r17	UTSW	5	109,576,030 (GRCm39)	missense	probably damaging	0.97
R5652:Vmn2r17	UTSW	5	109,577,430 (GRCm39)	missense	probably benign	0.10
R5717:Vmn2r17	UTSW	5	109,575,140 (GRCm39)	missense	possibly damaging	0.94
R5735:Vmn2r17	UTSW	5	109,600,716 (GRCm39)	missense	possibly damaging	0.67
R5766:Vmn2r17	UTSW	5	109,575,139 (GRCm39)	missense	possibly damaging	0.46
R6645:Vmn2r17	UTSW	5	109,576,247 (GRCm39)	missense	probably damaging	1.00
R6786:Vmn2r17	UTSW	5	109,575,695 (GRCm39)	missense	probably benign	0.30
R6821:Vmn2r17	UTSW	5	109,577,331 (GRCm39)	missense	probably damaging	1.00
R6979:Vmn2r17	UTSW	5	109,576,265 (GRCm39)	missense	possibly damaging	0.46
R6984:Vmn2r17	UTSW	5	109,600,533 (GRCm39)	missense	probably benign	0.10
R7269:Vmn2r17	UTSW	5	109,576,337 (GRCm39)	missense	possibly damaging	0.88
R7509:Vmn2r17	UTSW	5	109,575,695 (GRCm39)	missense	probably benign	0.30
R7736:Vmn2r17	UTSW	5	109,600,757 (GRCm39)	missense	probably benign	0.05
R7789:Vmn2r17	UTSW	5	109,600,831 (GRCm39)	missense	possibly damaging	0.77
R7814:Vmn2r17	UTSW	5	109,575,739 (GRCm39)	missense	probably benign	0.07
R7847:Vmn2r17	UTSW	5	109,568,063 (GRCm39)	missense	probably damaging	1.00
R7863:Vmn2r17	UTSW	5	109,568,035 (GRCm39)	missense	probably benign
R7893:Vmn2r17	UTSW	5	109,575,944 (GRCm39)	missense	probably benign	0.05
R8234:Vmn2r17	UTSW	5	109,601,235 (GRCm39)	missense	probably benign	0.01
R8382:Vmn2r17	UTSW	5	109,576,387 (GRCm39)	missense	probably benign	0.01
R8435:Vmn2r17	UTSW	5	109,576,172 (GRCm39)	missense	probably benign	0.01
R8465:Vmn2r17	UTSW	5	109,600,691 (GRCm39)	missense	probably damaging	0.99
R8555:Vmn2r17	UTSW	5	109,600,810 (GRCm39)	missense	probably damaging	0.99
R8900:Vmn2r17	UTSW	5	109,575,863 (GRCm39)	missense	probably benign	0.25
R9293:Vmn2r17	UTSW	5	109,600,712 (GRCm39)	missense	probably damaging	1.00
R9308:Vmn2r17	UTSW	5	109,600,505 (GRCm39)	missense	probably damaging	0.98
R9378:Vmn2r17	UTSW	5	109,575,732 (GRCm39)	missense	possibly damaging	0.94
R9597:Vmn2r17	UTSW	5	109,575,669 (GRCm39)	missense	probably damaging	1.00

Posted On

2016-08-02