Incidental Mutation 'IGL03222:Xkr9'
ID 413678
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Xkr9
Ensembl Gene ENSMUSG00000067813
Gene Name X-linked Kx blood group related 9
Synonyms LOC381246
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.067) question?
Stock # IGL03222
Quality Score
Status
Chromosome 1
Chromosomal Location 13668771-13701723 bp(+) (GRCm38)
Type of Mutation nonsense
DNA Base Change (assembly) T to A at 13701281 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Tyrosine to Stop codon at position 340 (Y340*)
Ref Sequence ENSEMBL: ENSMUSP00000085900 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088542]
AlphaFold Q5GH62
Predicted Effect probably null
Transcript: ENSMUST00000088542
AA Change: Y340*
SMART Domains Protein: ENSMUSP00000085900
Gene: ENSMUSG00000067813
AA Change: Y340*

DomainStartEndE-ValueType
Pfam:XK-related 9 346 2.8e-87 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 22 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921511C20Rik A G X: 127,395,470 D344G probably benign Het
Aqr A T 2: 114,121,256 L877Q probably damaging Het
Ctr9 T C 7: 111,043,050 Y328H probably benign Het
Ebf2 A G 14: 67,411,992 probably null Het
Ebpl A G 14: 61,342,233 probably benign Het
Efcab5 A T 11: 77,137,367 D515E probably benign Het
Gon4l A G 3: 88,895,643 N1187S possibly damaging Het
Hmces A G 6: 87,925,692 R172G probably damaging Het
Ighv14-2 T C 12: 113,994,494 D109G possibly damaging Het
Kcnn1 C T 8: 70,848,199 R423H probably damaging Het
Muc13 T C 16: 33,798,965 S28P unknown Het
Olfr495 A T 7: 108,395,186 D22V possibly damaging Het
Olfr862 G T 9: 19,884,199 Y35* probably null Het
Polg T C 7: 79,454,656 T824A probably damaging Het
Rapgef2 A T 3: 79,087,995 V782D probably damaging Het
Rin2 T A 2: 145,860,195 C270* probably null Het
Sdk2 C A 11: 113,838,431 V1107L probably benign Het
Sema5a T A 15: 32,628,158 V539E probably benign Het
Tiam2 T C 17: 3,438,708 S764P probably damaging Het
Tnfrsf11a A G 1: 105,821,490 Y211C probably damaging Het
Ttn T C 2: 76,755,739 T21883A probably damaging Het
Xkr5 T C 8: 18,937,299 T117A probably damaging Het
Other mutations in Xkr9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01990:Xkr9 APN 1 13700979 missense probably benign 0.00
IGL02090:Xkr9 APN 1 13701376 missense probably damaging 1.00
IGL02405:Xkr9 APN 1 13672773 splice site probably benign
IGL02523:Xkr9 APN 1 13684250 missense probably benign 0.01
IGL02792:Xkr9 APN 1 13700803 missense probably damaging 1.00
IGL02820:Xkr9 APN 1 13700949 missense probably benign
IGL02821:Xkr9 APN 1 13672575 missense probably damaging 1.00
IGL03170:Xkr9 APN 1 13700812 missense possibly damaging 0.72
R0044:Xkr9 UTSW 1 13684062 nonsense probably null
R0044:Xkr9 UTSW 1 13684062 nonsense probably null
R0595:Xkr9 UTSW 1 13700784 missense probably benign 0.02
R1337:Xkr9 UTSW 1 13701124 missense possibly damaging 0.94
R1670:Xkr9 UTSW 1 13700943 missense probably damaging 0.97
R5007:Xkr9 UTSW 1 13701163 missense probably damaging 0.98
R6133:Xkr9 UTSW 1 13684135 missense probably benign 0.01
R6302:Xkr9 UTSW 1 13672502 missense probably damaging 1.00
R8153:Xkr9 UTSW 1 13684139 missense probably benign 0.10
R8440:Xkr9 UTSW 1 13701379 missense probably benign 0.31
R8520:Xkr9 UTSW 1 13701379 missense probably benign 0.31
R8823:Xkr9 UTSW 1 13672608 missense probably benign 0.43
R8985:Xkr9 UTSW 1 13700766 missense probably benign
R9084:Xkr9 UTSW 1 13672509 missense probably benign 0.15
R9441:Xkr9 UTSW 1 13701363 missense possibly damaging 0.94
R9658:Xkr9 UTSW 1 13701094 missense probably damaging 1.00
X0025:Xkr9 UTSW 1 13672634 missense probably benign 0.43
Posted On 2016-08-02