Incidental Mutation 'IGL03243:Trav7d-4'
ID414326
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Trav7d-4
Ensembl Gene ENSMUSG00000094023
Gene NameT cell receptor alpha variable 7D-4
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.109) question?
Stock #IGL03243
Quality Score
Status
Chromosome14
Chromosomal Location52769753-52770390 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) C to A at 52770098 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000136110 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000178768]
Predicted Effect probably benign
Transcript: ENSMUST00000178768
SMART Domains Protein: ENSMUSP00000136110
Gene: ENSMUSG00000094023

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
IGv 38 111 2.74e-10 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000197998
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam26a T C 8: 43,568,696 T586A probably benign Het
Agtr1b T C 3: 20,315,795 T216A probably benign Het
Ankdd1a T C 9: 65,501,470 R505G probably benign Het
Anxa3 A T 5: 96,828,692 probably benign Het
Atp6v1c2 C T 12: 17,289,121 V210I probably benign Het
BC034090 G A 1: 155,225,655 P288S possibly damaging Het
Catsper2 T C 2: 121,406,819 H200R probably benign Het
Cntnap5c G T 17: 58,102,176 A470S probably benign Het
Fcho2 G A 13: 98,777,384 probably benign Het
Frem1 A C 4: 83,013,969 L165R probably damaging Het
Gm5155 A T 7: 17,918,649 noncoding transcript Het
Gpn1 G A 5: 31,510,831 probably null Het
Gpr179 T C 11: 97,351,475 N181S probably benign Het
Heatr5b A T 17: 78,763,080 probably benign Het
Kat6a A G 8: 22,910,222 N333S possibly damaging Het
Lrp5 T C 19: 3,630,159 T442A probably benign Het
Myo15 G T 11: 60,496,518 L722F probably damaging Het
Nlrp9c T G 7: 26,365,032 D957A probably damaging Het
Nupl1 T A 14: 60,221,616 T521S probably benign Het
Olfr58 T G 9: 19,783,268 I45S probably damaging Het
Plek C A 11: 16,995,319 V4L possibly damaging Het
Sell T A 1: 164,065,342 H42Q possibly damaging Het
Slfn8 A T 11: 83,003,707 I702K probably damaging Het
Svep1 T C 4: 58,133,387 I573V probably benign Het
Tgm1 T A 14: 55,705,907 I526F probably damaging Het
Tmem30c A T 16: 57,276,150 S203T probably benign Het
Tox T C 4: 6,697,597 N402S possibly damaging Het
Unc13d A T 11: 116,067,844 V784D probably benign Het
Vmn2r68 A G 7: 85,233,755 V263A possibly damaging Het
Zfp385c A T 11: 100,634,747 V56D probably damaging Het
Znrf2 A T 6: 54,884,769 I222L possibly damaging Het
Other mutations in Trav7d-4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02997:Trav7d-4 APN 14 52770256 missense probably damaging 0.97
IGL03014:Trav7d-4 UTSW 14 52769896 missense unknown
R2964:Trav7d-4 UTSW 14 52770127 nonsense probably null
R2966:Trav7d-4 UTSW 14 52770127 nonsense probably null
R3803:Trav7d-4 UTSW 14 52770118 nonsense probably null
R5689:Trav7d-4 UTSW 14 52770194 missense probably damaging 0.98
R6408:Trav7d-4 UTSW 14 52770167 missense probably damaging 0.98
R6905:Trav7d-4 UTSW 14 52770313 missense possibly damaging 0.93
Z1176:Trav7d-4 UTSW 14 52770113 missense probably damaging 1.00
Posted On2016-08-02