Incidental Mutation 'IGL03245:Cuedc1'
ID414389
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cuedc1
Ensembl Gene ENSMUSG00000018378
Gene NameCUE domain containing 1
SynonymsC330016O16Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL03245
Quality Score
Status
Chromosome11
Chromosomal Location88098058-88194140 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 88177262 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000120867 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000018522] [ENSMUST00000154812]
Predicted Effect probably benign
Transcript: ENSMUST00000018522
SMART Domains Protein: ENSMUSP00000018522
Gene: ENSMUSG00000018378

DomainStartEndE-ValueType
low complexity region 6 33 N/A INTRINSIC
CUE 50 92 6.55e-15 SMART
low complexity region 94 110 N/A INTRINSIC
low complexity region 121 136 N/A INTRINSIC
low complexity region 207 222 N/A INTRINSIC
low complexity region 331 340 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000133149
Predicted Effect probably benign
Transcript: ENSMUST00000154812
SMART Domains Protein: ENSMUSP00000120867
Gene: ENSMUSG00000018378

DomainStartEndE-ValueType
low complexity region 6 33 N/A INTRINSIC
CUE 50 92 6.55e-15 SMART
low complexity region 94 110 N/A INTRINSIC
low complexity region 121 136 N/A INTRINSIC
low complexity region 207 222 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 22 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akap13 C T 7: 75,609,752 A708V probably damaging Het
Cdh3 A G 8: 106,552,999 N749S probably damaging Het
Col3a1 G A 1: 45,331,109 probably benign Het
Csmd2 T A 4: 128,509,122 S2334R probably benign Het
Cubn T C 2: 13,355,689 T1741A probably benign Het
Cutc T C 19: 43,768,182 S228P possibly damaging Het
Dnmt1 G T 9: 20,915,760 N1013K probably damaging Het
Dst G T 1: 34,211,148 probably null Het
Lamc2 A T 1: 153,133,757 probably null Het
Mettl25 T C 10: 105,826,497 N204S possibly damaging Het
Micall2 G A 5: 139,719,259 H107Y probably damaging Het
Olfr1155 T A 2: 87,942,742 R295S possibly damaging Het
Olfr461 A G 6: 40,544,142 V279A probably damaging Het
Olfr945 T A 9: 39,257,998 I225F probably damaging Het
Ptger4 A T 15: 5,235,107 I331N probably damaging Het
Rad54l2 A G 9: 106,703,628 F898S probably damaging Het
Smr2 A G 5: 88,108,850 N129S probably benign Het
Tmeff2 T C 1: 51,181,817 F317S probably benign Het
Trpm6 A T 19: 18,877,701 E1908V probably damaging Het
Ugt2a3 G A 5: 87,336,580 P195L probably damaging Het
Xpo7 T A 14: 70,688,294 D436V probably damaging Het
Zfp804b C A 5: 6,772,253 S234I possibly damaging Het
Other mutations in Cuedc1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01129:Cuedc1 APN 11 88183254 missense possibly damaging 0.56
IGL02103:Cuedc1 APN 11 88188799 missense probably damaging 0.99
IGL02325:Cuedc1 APN 11 88170173 missense probably null 1.00
IGL03001:Cuedc1 APN 11 88182489 missense probably benign 0.02
R0242:Cuedc1 UTSW 11 88184621 splice site probably benign
R0511:Cuedc1 UTSW 11 88183405 missense probably damaging 1.00
R1013:Cuedc1 UTSW 11 88188027 missense possibly damaging 0.68
R1382:Cuedc1 UTSW 11 88177363 missense probably benign 0.08
R2004:Cuedc1 UTSW 11 88177390 missense probably damaging 1.00
R5320:Cuedc1 UTSW 11 88177310 missense probably damaging 1.00
R5381:Cuedc1 UTSW 11 88187986 splice site probably null
R5782:Cuedc1 UTSW 11 88170032 missense probably damaging 1.00
R6282:Cuedc1 UTSW 11 88183402 missense probably damaging 1.00
R6918:Cuedc1 UTSW 11 88187073 missense probably benign 0.00
R7329:Cuedc1 UTSW 11 88169866 missense unknown
Posted On2016-08-02