Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03246:Mageb11'

414407

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mageb11

Ensembl Gene

ENSMUSG00000091497

Gene Name

MAGE family member B11

Synonyms

LOC212952, Gm44

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL03246

Quality Score

Status

Chromosome

Chromosomal Location

89935748-89936740 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 89936008 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Glutamine at position 87 (H87Q)

Ref Sequence

ENSEMBL: ENSMUSP00000129722 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000172155]

AlphaFold

G3UW88

Predicted Effect

probably benign
Transcript: ENSMUST00000172155
AA Change: H87Q

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000129722
Gene: ENSMUSG00000091497
AA Change: H87Q

Domain	Start	End	E-Value	Type
MAGE_N	3	79	1.68e0	SMART
MAGE	98	268	7.16e-91	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921511C20Rik	T	A	X: 126,303,238 (GRCm39)	H392Q	probably benign	Het
Alox8	T	A	11: 69,076,841 (GRCm39)	I547L	probably damaging	Het
Capn13	T	C	17: 73,689,855 (GRCm39)	H52R	probably benign	Het
Cfap57	T	A	4: 118,433,842 (GRCm39)	I979L	probably benign	Het
Ctdnep1	T	C	11: 69,875,156 (GRCm39)		probably benign	Het
Ercc5	C	A	1: 44,206,241 (GRCm39)	P385T	probably damaging	Het
Fam98a	C	T	17: 75,845,848 (GRCm39)	M299I	probably damaging	Het
Flcn	A	T	11: 59,684,936 (GRCm39)	I505N	possibly damaging	Het
Fn1	G	A	1: 71,663,455 (GRCm39)	T1011I	possibly damaging	Het
Klhl28	T	C	12: 65,004,060 (GRCm39)	D151G	probably benign	Het
Klk13	T	A	7: 43,370,422 (GRCm39)	N28K	probably damaging	Het
Macc1	T	C	12: 119,410,420 (GRCm39)	V396A	probably benign	Het
Magi2	T	A	5: 20,563,948 (GRCm39)	I360K	probably damaging	Het
Myh7b	T	C	2: 155,459,792 (GRCm39)	I251T	probably damaging	Het
Naalad2	A	T	9: 18,296,395 (GRCm39)	I85K	possibly damaging	Het
Or5ae1	T	C	7: 84,565,919 (GRCm39)	C311R	probably benign	Het
Pbrm1	A	T	14: 30,832,506 (GRCm39)	M1490L	probably benign	Het
Pclo	C	T	5: 14,727,631 (GRCm39)		probably benign	Het
Pdcd6ip	T	C	9: 113,507,485 (GRCm39)	K357R	possibly damaging	Het
Pnpla6	C	T	8: 3,581,530 (GRCm39)	T601I	probably benign	Het
Pof1b	A	T	X: 111,557,817 (GRCm39)	N366K	probably benign	Het
Prr9	A	G	3: 92,030,286 (GRCm39)		probably benign	Het
Ptprz1	G	T	6: 22,986,159 (GRCm39)	A320S	probably damaging	Het
Ripor1	A	G	8: 106,342,490 (GRCm39)	Y187C	possibly damaging	Het
Rnf13	A	G	3: 57,676,471 (GRCm39)	E42G	probably damaging	Het
Sdf4	T	C	4: 156,085,154 (GRCm39)	V163A	probably benign	Het
Smc2	C	T	4: 52,440,301 (GRCm39)	Q16*	probably null	Het
Srsf3-ps	T	A	11: 98,516,119 (GRCm39)	R85*	probably null	Het
Tbck	T	A	3: 132,480,331 (GRCm39)	C737S	probably benign	Het
Tra2a	A	T	6: 49,226,019 (GRCm39)	Y140*	probably null	Het
Vcpip1	A	C	1: 9,816,182 (GRCm39)	L734V	probably benign	Het
Vmn1r87	G	A	7: 12,866,288 (GRCm39)		probably benign	Het

Other mutations in Mageb11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02944:Mageb11	APN	X	89,935,868 (GRCm39)	missense	probably benign	0.00
R1385:Mageb11	UTSW	X	89,935,874 (GRCm39)	missense	probably benign	0.01

Posted On

2016-08-02