Incidental Mutation 'IGL03249:Galntl6'
ID414522
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Galntl6
Ensembl Gene ENSMUSG00000096914
Gene NameUDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.070) question?
Stock #IGL03249
Quality Score
Status
Chromosome8
Chromosomal Location57774052-58912640 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) G to T at 57777176 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000145321 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000204067] [ENSMUST00000204128]
Predicted Effect probably benign
Transcript: ENSMUST00000098757
SMART Domains Protein: ENSMUSP00000096353
Gene: ENSMUSG00000096914

DomainStartEndE-ValueType
Pfam:Glycos_transf_2 1 144 1.6e-18 PFAM
Pfam:Glyco_transf_7C 113 187 3.6e-12 PFAM
RICIN 268 401 7.9e-21 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000204067
SMART Domains Protein: ENSMUSP00000145016
Gene: ENSMUSG00000096914

DomainStartEndE-ValueType
Pfam:Ricin_B_lectin 1 47 6.2e-9 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000204128
SMART Domains Protein: ENSMUSP00000145321
Gene: ENSMUSG00000096914

DomainStartEndE-ValueType
transmembrane domain 13 31 N/A INTRINSIC
Pfam:Glyco_tranf_2_3 140 404 2.1e-9 PFAM
Pfam:Glycos_transf_2 143 328 7.3e-33 PFAM
Pfam:Glyco_tranf_2_2 143 356 1.2e-8 PFAM
Pfam:Glyco_transf_7C 297 371 6.2e-12 PFAM
RICIN 452 585 7.9e-21 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 18 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2410002F23Rik A G 7: 44,250,725 Y18C probably damaging Het
Abcc4 A G 14: 118,627,706 probably benign Het
Acnat2 T C 4: 49,381,787 K202E probably benign Het
Arid2 A T 15: 96,401,965 R1786S probably damaging Het
Atp2a1 C T 7: 126,462,805 E40K probably benign Het
Cdc23 A G 18: 34,644,016 probably benign Het
Ctnnd2 A G 15: 30,683,236 D461G probably benign Het
Gcc2 T A 10: 58,270,992 Y583* probably null Het
Olfr740 T C 14: 50,453,211 V53A probably damaging Het
Plekhg2 C A 7: 28,368,002 R281L probably damaging Het
Rbm27 A G 18: 42,301,747 D292G probably damaging Het
Ryr3 A T 2: 112,640,656 M4594K probably benign Het
Sec22a T C 16: 35,347,763 Y126C probably damaging Het
Svopl T C 6: 38,017,053 T348A probably benign Het
Svs1 A T 6: 48,988,369 H437L probably benign Het
Tecta T C 9: 42,391,886 E150G probably benign Het
Ttc8 T G 12: 98,943,821 probably benign Het
Zfp51 T A 17: 21,463,439 N105K probably damaging Het
Other mutations in Galntl6
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00489:Galntl6 APN 8 57857540 missense probably damaging 1.00
IGL00557:Galntl6 APN 8 58911417 missense possibly damaging 0.71
IGL01140:Galntl6 APN 8 57958322 missense probably damaging 1.00
IGL01412:Galntl6 APN 8 57777294 missense probably damaging 0.99
IGL01458:Galntl6 APN 8 58427709 missense probably damaging 1.00
IGL01575:Galntl6 APN 8 58427676 intron probably benign
IGL01700:Galntl6 APN 8 57958460 splice site probably benign
IGL01710:Galntl6 APN 8 58535968 missense probably damaging 0.97
IGL02611:Galntl6 APN 8 57958416 missense probably damaging 1.00
IGL02880:Galntl6 APN 8 57804272 missense probably benign 0.44
IGL03129:Galntl6 APN 8 58427716 missense probably damaging 1.00
IGL03215:Galntl6 APN 8 58911402 missense probably benign 0.00
Indubitably UTSW 8 58427770 missense probably damaging 1.00
PIT4677001:Galntl6 UTSW 8 57857587 missense probably damaging 1.00
R0600:Galntl6 UTSW 8 57837183 splice site probably null
R0731:Galntl6 UTSW 8 58535984 missense probably benign
R0961:Galntl6 UTSW 8 58911340 missense probably benign
R1381:Galntl6 UTSW 8 58472955 missense probably damaging 0.99
R2137:Galntl6 UTSW 8 58535905 critical splice donor site probably null
R4632:Galntl6 UTSW 8 58427823 missense probably damaging 1.00
R4731:Galntl6 UTSW 8 58427813 missense probably damaging 1.00
R4732:Galntl6 UTSW 8 58427813 missense probably damaging 1.00
R4733:Galntl6 UTSW 8 58427813 missense probably damaging 1.00
R4920:Galntl6 UTSW 8 58427773 missense probably damaging 0.97
R4964:Galntl6 UTSW 8 58699911 intron probably benign
R5357:Galntl6 UTSW 8 57884463 missense probably damaging 0.99
R5526:Galntl6 UTSW 8 58472970 missense probably benign
R5951:Galntl6 UTSW 8 57962402 missense probably benign 0.06
R5965:Galntl6 UTSW 8 57857531 missense probably benign 0.03
R6260:Galntl6 UTSW 8 57884481 missense probably damaging 1.00
R6368:Galntl6 UTSW 8 58911441 missense probably damaging 1.00
R6695:Galntl6 UTSW 8 58427770 missense probably damaging 1.00
R7593:Galntl6 UTSW 8 57777259 missense probably damaging 1.00
Posted On2016-08-02