Incidental Mutation 'IGL03252:Tas2r125'
ID 414573
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r125
Ensembl Gene ENSMUSG00000059410
Gene Name taste receptor, type 2, member 125
Synonyms mGR25, Tas2r25, mt2r59, T2R26
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.066) question?
Stock # IGL03252
Quality Score
Status
Chromosome 6
Chromosomal Location 132909651-132910587 bp(+) (GRCm38)
Type of Mutation splice site (3 bp from exon)
DNA Base Change (assembly) A to G at 132910590 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000075483 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000076119]
AlphaFold Q7M710
Predicted Effect probably null
Transcript: ENSMUST00000076119
SMART Domains Protein: ENSMUSP00000075483
Gene: ENSMUSG00000059410

DomainStartEndE-ValueType
Pfam:TAS2R 1 300 1.1e-90 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
B4galnt2 A G 11: 95,873,931 S237P probably damaging Het
Btla A G 16: 45,239,146 H71R possibly damaging Het
Calml3 T A 13: 3,803,759 K149* probably null Het
Cyp2c29 T C 19: 39,287,175 W20R probably damaging Het
Dnah8 G A 17: 30,673,920 probably null Het
Elf3 T C 1: 135,254,953 T345A probably damaging Het
Erc2 T C 14: 28,475,649 probably benign Het
Gm10375 C T 14: 43,604,832 C147Y probably damaging Het
Gsdma2 A G 11: 98,649,090 R13G probably damaging Het
Hist1h3a G A 13: 23,761,960 probably null Het
Ighg3 G T 12: 113,360,564 P101H unknown Het
L3mbtl3 A G 10: 26,331,812 probably benign Het
Micall2 T C 5: 139,716,726 N254S probably benign Het
Myh4 A T 11: 67,252,216 D990V probably damaging Het
Ncapd3 T A 9: 27,051,449 F394I probably damaging Het
Nek1 C T 8: 61,072,330 Q601* probably null Het
Olfr1281 T A 2: 111,328,780 Y120* probably null Het
Olfr668 C T 7: 104,925,387 V126I probably benign Het
Plcb1 C T 2: 135,370,428 P980S probably benign Het
Puf60 T C 15: 76,071,850 D224G probably damaging Het
Pus7l T A 15: 94,525,810 H586L probably benign Het
Rims2 T C 15: 39,452,352 S585P probably benign Het
Rxfp1 T A 3: 79,667,683 D207V probably benign Het
Scgb2b7 A T 7: 31,705,081 C65S probably damaging Het
Sptlc2 A G 12: 87,355,657 I165T probably benign Het
Sult2a3 A G 7: 14,067,634 V260A probably damaging Het
Tbx18 T A 9: 87,705,580 I495F probably damaging Het
Top2b A T 14: 16,393,163 N274I possibly damaging Het
Vmn2r53 T G 7: 12,606,391 T52P probably damaging Het
Other mutations in Tas2r125
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0090:Tas2r125 UTSW 6 132910398 missense probably benign 0.21
R0725:Tas2r125 UTSW 6 132910122 missense probably benign 0.44
R1901:Tas2r125 UTSW 6 132910176 missense probably benign 0.13
R1902:Tas2r125 UTSW 6 132910176 missense probably benign 0.13
R2679:Tas2r125 UTSW 6 132910227 missense probably benign 0.43
R4770:Tas2r125 UTSW 6 132909787 missense probably damaging 1.00
R4784:Tas2r125 UTSW 6 132909903 missense probably benign 0.16
R5795:Tas2r125 UTSW 6 132909658 missense probably damaging 1.00
R7535:Tas2r125 UTSW 6 132910324 missense probably damaging 1.00
R7820:Tas2r125 UTSW 6 132909878 missense probably benign 0.02
R9071:Tas2r125 UTSW 6 132910437 missense probably benign 0.00
Z1177:Tas2r125 UTSW 6 132909656 missense probably damaging 0.99
Posted On 2016-08-02