Incidental Mutation 'IGL03253:Gm8394'
ID414587
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm8394
Ensembl Gene ENSMUSG00000050490
Gene Namepredicted gene 8394
Synonyms
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.889) question?
Stock #IGL03253
Quality Score
Status
Chromosome10
Chromosomal Location85313488-85314439 bp(+) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) A to G at 85313692 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000079684
SMART Domains Protein: ENSMUSP00000078625
Gene: ENSMUSG00000050490

DomainStartEndE-ValueType
Proteasome_A_N 8 30 6.32e-8 SMART
Pfam:Proteasome 31 220 5.6e-57 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2700049A03Rik G A 12: 71,140,883 V98I probably benign Het
Aadacl4 G T 4: 144,623,288 V372L probably benign Het
Acp5 A T 9: 22,127,787 I210N probably damaging Het
Ash1l G A 3: 88,984,674 A1287T probably damaging Het
AU018091 A T 7: 3,164,172 C72S probably damaging Het
Ccdc178 G A 18: 21,845,011 Q800* probably null Het
Cd47 A T 16: 49,894,198 H190L probably benign Het
Clca2 T A 3: 145,071,563 H849L probably benign Het
Cmya5 G A 13: 93,091,270 Q2437* probably null Het
Depdc5 T C 5: 32,868,813 probably benign Het
Erp44 T A 4: 48,208,750 I237F probably benign Het
Gramd1a C T 7: 31,139,846 W8* probably null Het
Gucy2d C T 7: 98,451,664 A398V probably benign Het
Hecw2 T C 1: 53,832,716 E1357G possibly damaging Het
Ighv1-11 T C 12: 114,615,848 probably benign Het
Itih3 A C 14: 30,911,923 probably null Het
Kcnk5 A G 14: 20,142,337 V252A probably benign Het
Kif14 A G 1: 136,487,460 E771G probably damaging Het
Klc1 T C 12: 111,781,644 probably benign Het
Myom3 A G 4: 135,783,097 E567G possibly damaging Het
Olfr1242 A G 2: 89,493,799 V171A possibly damaging Het
Pfpl A G 19: 12,430,029 D548G probably damaging Het
Rad54l2 A G 9: 106,704,223 V833A probably damaging Het
Scnn1g A T 7: 121,737,933 K6* probably null Het
Sun1 T C 5: 139,223,586 probably benign Het
Synj2 A G 17: 6,003,159 probably null Het
Ttc1 T A 11: 43,738,823 E172V probably benign Het
Ttn A G 2: 76,769,020 V19215A probably damaging Het
Vwa3a A G 7: 120,778,869 I461V probably benign Het
Wdr73 A G 7: 80,897,946 M110T probably benign Het
Zfand4 A T 6: 116,284,809 D111V probably damaging Het
Zscan4f T A 7: 11,401,343 N225K probably benign Het
Other mutations in Gm8394
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01336:Gm8394 APN 10 85314164 exon noncoding transcript
IGL01467:Gm8394 APN 10 85314122 exon noncoding transcript
IGL02638:Gm8394 APN 10 85313834 exon noncoding transcript
R1929:Gm8394 UTSW 10 85313731 exon noncoding transcript
R2271:Gm8394 UTSW 10 85313731 exon noncoding transcript
R2893:Gm8394 UTSW 10 85313984 exon noncoding transcript
R4689:Gm8394 UTSW 10 85314201 exon noncoding transcript
R4711:Gm8394 UTSW 10 85313803 exon noncoding transcript
R5537:Gm8394 UTSW 10 85314049 exon noncoding transcript
R5934:Gm8394 UTSW 10 85314281 exon noncoding transcript
T0722:Gm8394 UTSW 10 85313593 exon noncoding transcript
Posted On2016-08-02