Incidental Mutation 'IGL03255:AY761184'
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ID414610
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol AY761184
Ensembl Gene ENSMUSG00000058618
Gene NamecDNA sequence AY761184
SynonymsCRS1C-3
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.079) question?
Stock #IGL03255
Quality Score
Status
Chromosome8
Chromosomal Location21702519-21703645 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 21703518 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 29 (T29A)
Ref Sequence ENSEMBL: ENSMUSP00000071783 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000071886]
Predicted Effect possibly damaging
Transcript: ENSMUST00000071886
AA Change: T29A

PolyPhen 2 Score 0.707 (Sensitivity: 0.86; Specificity: 0.92)
SMART Domains Protein: ENSMUSP00000071783
Gene: ENSMUSG00000058618
AA Change: T29A

DomainStartEndE-ValueType
Pfam:Defensin_propep 1 51 1.8e-23 PFAM
low complexity region 67 91 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000121457
Predicted Effect noncoding transcript
Transcript: ENSMUST00000158155
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1600012P17Rik A G 1: 158,969,351 noncoding transcript Het
Alpk3 A G 7: 81,092,562 D709G probably benign Het
Capn3 G T 2: 120,489,708 R309L probably damaging Het
Card11 T C 5: 140,898,331 I398V possibly damaging Het
Cps1 T A 1: 67,145,801 Y162* probably null Het
Defa26 A T 8: 21,618,241 D20V probably damaging Het
Dnah8 T G 17: 30,741,381 L2244R probably damaging Het
Fhad1 T A 4: 141,972,880 N353I possibly damaging Het
Flt1 T A 5: 147,588,521 probably benign Het
Glyr1 G A 16: 5,048,757 probably null Het
Gm10220 A G 5: 26,116,901 S258P possibly damaging Het
Lama3 A T 18: 12,539,703 D845V probably damaging Het
Myh2 T A 11: 67,193,225 L1558Q probably damaging Het
Nelfb G T 2: 25,203,195 H482N probably benign Het
Olfr290 T C 7: 84,916,517 L246P possibly damaging Het
Olfr482 A G 7: 108,094,817 V251A probably damaging Het
Ppfia2 A G 10: 106,896,507 T972A possibly damaging Het
Slc5a4a G A 10: 76,150,512 V85M probably damaging Het
Slc6a12 T G 6: 121,354,287 C166G probably damaging Het
Tm7sf3 T C 6: 146,606,120 probably benign Het
Tmem94 G T 11: 115,792,068 probably benign Het
Tmod2 T C 9: 75,577,258 probably benign Het
Tmprss11c T A 5: 86,271,482 I73F probably damaging Het
Vmn1r10 A G 6: 57,113,926 M168V probably benign Het
Vmn2r77 T A 7: 86,811,923 M819K probably benign Het
Vmo1 C T 11: 70,514,410 probably null Het
Ywhab A G 2: 164,014,016 D104G probably benign Het
Other mutations in AY761184
AlleleSourceChrCoordTypePredicted EffectPPH Score
R2090:AY761184 UTSW 8 21702789 missense possibly damaging 0.96
R2426:AY761184 UTSW 8 21702637 missense possibly damaging 0.72
R4111:AY761184 UTSW 8 21702663 missense possibly damaging 0.53
R6339:AY761184 UTSW 8 21703469 missense possibly damaging 0.86
R7874:AY761184 UTSW 8 21702796 missense possibly damaging 0.53
R7957:AY761184 UTSW 8 21702796 missense possibly damaging 0.53
Posted On2016-08-02