Incidental Mutation 'IGL03261:Vmn1r120'
ID414803
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r120
Ensembl Gene ENSMUSG00000093986
Gene Namevomeronasal 1 receptor 120
SynonymsGm5730
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.057) question?
Stock #IGL03261
Quality Score
Status
Chromosome7
Chromosomal Location21052867-21053784 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 21053525 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Proline at position 87 (L87P)
Ref Sequence ENSEMBL: ENSMUSP00000100837 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000105202]
Predicted Effect probably damaging
Transcript: ENSMUST00000105202
AA Change: L87P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000100837
Gene: ENSMUSG00000093986
AA Change: L87P

DomainStartEndE-ValueType
Pfam:TAS2R 8 297 2.3e-15 PFAM
Pfam:7tm_1 31 286 3.6e-6 PFAM
Pfam:V1R 41 296 6.4e-13 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310022A10Rik T G 7: 27,580,438 Y281* probably null Het
5830411N06Rik A G 7: 140,294,833 H408R probably benign Het
Adamts3 T C 5: 89,882,897 probably benign Het
Afp T C 5: 90,491,751 probably null Het
Ap1g2 T C 14: 55,100,530 T634A probably benign Het
Cidec A G 6: 113,433,172 V32A probably benign Het
Dip2a G A 10: 76,305,148 P315S possibly damaging Het
Hoxc11 T C 15: 102,954,743 V73A probably benign Het
Jmjd1c A G 10: 67,232,070 Y1784C probably damaging Het
Mmp21 A G 7: 133,674,674 V480A probably benign Het
Nek4 C T 14: 30,975,290 T471I probably benign Het
Nr4a2 A G 2: 57,110,187 V299A probably benign Het
Olfr761 A T 17: 37,952,806 S73T possibly damaging Het
Olfr774 A G 10: 129,238,403 T85A possibly damaging Het
Ptprg A G 14: 12,225,552 D505G probably damaging Het
Rag2 A G 2: 101,630,263 D306G probably damaging Het
Rpap2 T A 5: 107,598,560 S38T possibly damaging Het
Scgb2b7 A T 7: 31,705,081 C65S probably damaging Het
Slx4ip A T 2: 137,046,739 R113S probably benign Het
Smyd5 T A 6: 85,432,018 M5K probably benign Het
Stkld1 A T 2: 26,952,777 H587L probably benign Het
Taf4b A G 18: 14,821,528 T554A probably benign Het
Tex16 C A X: 112,118,855 D350E possibly damaging Het
Tex38 T C 4: 115,780,526 K27E possibly damaging Het
Trdv4 T C 14: 54,075,418 L83P possibly damaging Het
Ugt2a3 G A 5: 87,336,580 P195L probably damaging Het
Zfp236 T C 18: 82,630,608 D916G possibly damaging Het
Other mutations in Vmn1r120
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00474:Vmn1r120 APN 7 21053010 missense probably benign 0.00
IGL02533:Vmn1r120 APN 7 21053138 missense probably damaging 1.00
R0539:Vmn1r120 UTSW 7 21053472 missense probably damaging 0.99
R0973:Vmn1r120 UTSW 7 21053016 missense probably damaging 1.00
R1831:Vmn1r120 UTSW 7 21053631 missense probably benign
R2034:Vmn1r120 UTSW 7 21052958 missense possibly damaging 0.56
R2149:Vmn1r120 UTSW 7 21052964 missense probably damaging 0.98
R3437:Vmn1r120 UTSW 7 21053657 missense probably damaging 1.00
R5449:Vmn1r120 UTSW 7 21053149 missense possibly damaging 0.53
R5548:Vmn1r120 UTSW 7 21053557 missense probably benign 0.01
R5730:Vmn1r120 UTSW 7 21053009 missense possibly damaging 0.80
R6305:Vmn1r120 UTSW 7 21053606 missense possibly damaging 0.95
R7348:Vmn1r120 UTSW 7 21053452 missense probably damaging 1.00
R8435:Vmn1r120 UTSW 7 21053632 missense probably benign 0.44
R8486:Vmn1r120 UTSW 7 21053102 missense probably benign
Posted On2016-08-02