Incidental Mutation 'R0463:Myom2'
| ID |
41490 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
038663-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.148)
|
| Stock # |
R0463 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 15154123 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 687
(V687A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000033842
AA Change: V687A
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: V687A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000117573
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135393
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522L14Rik |
A |
G |
5: 109,884,926 (GRCm39) |
|
probably benign |
Het |
| Abcd2 |
C |
T |
15: 91,043,327 (GRCm39) |
M620I |
probably benign |
Het |
| Ada |
T |
A |
2: 163,572,271 (GRCm39) |
I243F |
probably benign |
Het |
| Adam12 |
T |
C |
7: 133,576,145 (GRCm39) |
|
probably null |
Het |
| Adarb2 |
A |
T |
13: 8,253,224 (GRCm39) |
|
probably benign |
Het |
| Adk |
A |
C |
14: 21,473,604 (GRCm39) |
Q287P |
probably benign |
Het |
| Ahnak |
A |
G |
19: 8,986,771 (GRCm39) |
|
probably benign |
Het |
| Aoc3 |
C |
T |
11: 101,222,432 (GRCm39) |
R223W |
probably damaging |
Het |
| Aqp11 |
T |
C |
7: 97,378,228 (GRCm39) |
D229G |
probably benign |
Het |
| Arhgap28 |
A |
G |
17: 68,203,220 (GRCm39) |
S78P |
probably damaging |
Het |
| Bfsp2 |
T |
A |
9: 103,303,854 (GRCm39) |
E383D |
possibly damaging |
Het |
| Bmpr1b |
A |
T |
3: 141,563,191 (GRCm39) |
V251D |
possibly damaging |
Het |
| Calhm1 |
C |
T |
19: 47,132,280 (GRCm39) |
V112I |
probably benign |
Het |
| Catsperd |
A |
G |
17: 56,966,554 (GRCm39) |
D508G |
probably damaging |
Het |
| Cfap54 |
A |
G |
10: 92,710,805 (GRCm39) |
|
probably null |
Het |
| Cfap70 |
A |
T |
14: 20,498,631 (GRCm39) |
Y19N |
probably damaging |
Het |
| Chga |
A |
T |
12: 102,529,210 (GRCm39) |
R396* |
probably null |
Het |
| Cntnap3 |
T |
C |
13: 64,926,690 (GRCm39) |
E560G |
probably damaging |
Het |
| Csmd1 |
T |
C |
8: 15,971,759 (GRCm39) |
T3024A |
probably damaging |
Het |
| Csrnp1 |
CCCTCCTCCTCCTCCTCCTC |
CCCTCCTCCTCCTCCTC |
9: 119,801,841 (GRCm39) |
|
probably benign |
Het |
| Cysltr1 |
A |
G |
X: 105,622,261 (GRCm39) |
V75A |
possibly damaging |
Het |
| Dnaaf11 |
T |
A |
15: 66,252,323 (GRCm39) |
M448L |
probably benign |
Het |
| Dnah2 |
A |
T |
11: 69,313,952 (GRCm39) |
M4140K |
probably damaging |
Het |
| Dph5 |
A |
G |
3: 115,722,352 (GRCm39) |
S277G |
probably benign |
Het |
| Eftud2 |
A |
T |
11: 102,755,597 (GRCm39) |
D203E |
probably damaging |
Het |
| Egf |
A |
G |
3: 129,499,882 (GRCm39) |
Y252H |
probably benign |
Het |
| Egf |
A |
G |
3: 129,531,198 (GRCm39) |
S126P |
probably damaging |
Het |
| Faf1 |
C |
T |
4: 109,748,138 (GRCm39) |
A481V |
probably benign |
Het |
| Fat2 |
A |
T |
11: 55,153,655 (GRCm39) |
V3519D |
probably damaging |
Het |
| Fbln7 |
C |
A |
2: 128,719,431 (GRCm39) |
A76E |
probably benign |
Het |
| Galnt1 |
A |
T |
18: 24,387,582 (GRCm39) |
K49N |
probably benign |
Het |
| Glb1 |
ACCC |
ACC |
9: 114,250,812 (GRCm39) |
|
probably null |
Het |
| Grk1 |
T |
C |
8: 13,459,279 (GRCm39) |
Y277H |
probably damaging |
Het |
| Hap1 |
A |
G |
11: 100,240,131 (GRCm39) |
L555P |
probably damaging |
Het |
| Ier3 |
T |
C |
17: 36,133,000 (GRCm39) |
I94T |
possibly damaging |
Het |
| Il11 |
T |
C |
7: 4,779,023 (GRCm39) |
T36A |
probably damaging |
Het |
| Il5ra |
A |
T |
6: 106,708,851 (GRCm39) |
D296E |
probably damaging |
Het |
| Itk |
A |
T |
11: 46,222,816 (GRCm39) |
V551E |
probably damaging |
Het |
| Kcna2 |
T |
A |
3: 107,012,476 (GRCm39) |
D352E |
probably benign |
Het |
| Kif5a |
A |
T |
10: 127,071,521 (GRCm39) |
S776T |
probably benign |
Het |
| Klrb1c |
T |
C |
6: 128,757,366 (GRCm39) |
E233G |
probably benign |
Het |
| Kpna7 |
T |
C |
5: 144,944,804 (GRCm39) |
K12R |
possibly damaging |
Het |
| Lhpp |
C |
T |
7: 132,212,406 (GRCm39) |
|
probably benign |
Het |
| Lhx8 |
A |
T |
3: 154,033,808 (GRCm39) |
|
probably null |
Het |
| Magel2 |
T |
A |
7: 62,027,778 (GRCm39) |
H227Q |
possibly damaging |
Het |
| Man1a |
A |
G |
10: 53,950,594 (GRCm39) |
V176A |
probably damaging |
Het |
| Mapkbp1 |
T |
A |
2: 119,853,632 (GRCm39) |
M1152K |
probably benign |
Het |
| Mcoln3 |
T |
A |
3: 145,846,331 (GRCm39) |
L547* |
probably null |
Het |
| Myof |
T |
C |
19: 37,904,952 (GRCm39) |
D1624G |
probably damaging |
Het |
| Nav1 |
C |
A |
1: 135,379,945 (GRCm39) |
V1586F |
possibly damaging |
Het |
| Ndufb8 |
T |
C |
19: 44,538,784 (GRCm39) |
E179G |
possibly damaging |
Het |
| Nfam1 |
T |
C |
15: 82,885,684 (GRCm39) |
T223A |
probably damaging |
Het |
| Nrcam |
T |
A |
12: 44,598,124 (GRCm39) |
V371E |
probably damaging |
Het |
| Nup210l |
A |
G |
3: 90,087,518 (GRCm39) |
Q1097R |
probably null |
Het |
| Obox5 |
T |
A |
7: 15,491,571 (GRCm39) |
M37K |
probably damaging |
Het |
| Obscn |
A |
T |
11: 58,952,356 (GRCm39) |
N4270K |
probably benign |
Het |
| Or4d2 |
G |
A |
11: 87,784,022 (GRCm39) |
H243Y |
probably damaging |
Het |
| Or5ak25 |
T |
A |
2: 85,268,630 (GRCm39) |
S291C |
probably damaging |
Het |
| Or6c1 |
A |
G |
10: 129,517,708 (GRCm39) |
M300T |
probably benign |
Het |
| Or8c15 |
G |
A |
9: 38,120,360 (GRCm39) |
A2T |
probably benign |
Het |
| Or8k16 |
T |
C |
2: 85,520,183 (GRCm39) |
S137P |
possibly damaging |
Het |
| Patj |
G |
A |
4: 98,562,545 (GRCm39) |
E1505K |
probably damaging |
Het |
| Pnliprp1 |
T |
A |
19: 58,726,628 (GRCm39) |
Y328* |
probably null |
Het |
| Ppp1r36 |
G |
A |
12: 76,465,741 (GRCm39) |
E43K |
probably damaging |
Het |
| Ptch1 |
C |
T |
13: 63,668,121 (GRCm39) |
V939I |
probably damaging |
Het |
| Rgs22 |
C |
A |
15: 36,093,084 (GRCm39) |
K396N |
probably damaging |
Het |
| Rsrc1 |
A |
T |
3: 67,088,194 (GRCm39) |
H176L |
probably damaging |
Het |
| Ryr3 |
A |
T |
2: 112,492,046 (GRCm39) |
F3743L |
probably damaging |
Het |
| Scn7a |
C |
T |
2: 66,506,084 (GRCm39) |
G1602R |
probably benign |
Het |
| Sftpc |
A |
T |
14: 70,760,110 (GRCm39) |
V49E |
probably damaging |
Het |
| Slc16a10 |
A |
G |
10: 39,916,612 (GRCm39) |
V430A |
probably benign |
Het |
| Slco4c1 |
A |
C |
1: 96,795,645 (GRCm39) |
S138A |
possibly damaging |
Het |
| Snd1 |
T |
C |
6: 28,724,955 (GRCm39) |
I501T |
probably benign |
Het |
| Stxbp2 |
T |
A |
8: 3,682,559 (GRCm39) |
D49E |
probably damaging |
Het |
| Sytl4 |
A |
T |
X: 132,862,936 (GRCm39) |
D16E |
probably benign |
Het |
| Tbc1d9b |
G |
A |
11: 50,035,894 (GRCm39) |
G130E |
probably benign |
Het |
| Tdrd6 |
T |
A |
17: 43,936,452 (GRCm39) |
D1532V |
probably damaging |
Het |
| Tekt1 |
T |
C |
11: 72,242,778 (GRCm39) |
D243G |
probably damaging |
Het |
| Tet2 |
A |
G |
3: 133,192,427 (GRCm39) |
L669S |
possibly damaging |
Het |
| Tnnt3 |
A |
G |
7: 142,066,072 (GRCm39) |
N201S |
probably benign |
Het |
| Trdn |
A |
G |
10: 33,342,417 (GRCm39) |
|
probably null |
Het |
| Trim36 |
T |
C |
18: 46,311,523 (GRCm39) |
E259G |
possibly damaging |
Het |
| Trpm1 |
C |
T |
7: 63,870,002 (GRCm39) |
P436S |
probably benign |
Het |
| Vmn1r183 |
T |
A |
7: 23,754,926 (GRCm39) |
L243Q |
probably damaging |
Het |
| Vps13b |
T |
C |
15: 35,597,555 (GRCm39) |
S1032P |
probably damaging |
Het |
| Vps37d |
T |
C |
5: 135,105,395 (GRCm39) |
E76G |
probably damaging |
Het |
| Vps72 |
A |
G |
3: 95,028,615 (GRCm39) |
H202R |
probably benign |
Het |
| Wdr75 |
T |
C |
1: 45,858,762 (GRCm39) |
S644P |
probably damaging |
Het |
| Wrn |
T |
A |
8: 33,770,843 (GRCm39) |
E697V |
possibly damaging |
Het |
| Xirp2 |
A |
G |
2: 67,345,262 (GRCm39) |
D2501G |
probably benign |
Het |
| Zfp472 |
T |
C |
17: 33,194,936 (GRCm39) |
W24R |
probably damaging |
Het |
| Zmym6 |
T |
C |
4: 127,016,565 (GRCm39) |
V782A |
probably damaging |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCAGGATCTCAGACTCTGACAC -3'
(R):5'- AGTAGAGGCACTAACGTGGTCTTCC -3'
Sequencing Primer
(F):5'- TCATTTACGACACTGAATACGAGGG -3'
(R):5'- TCCATATTTAATTGGTATGGTGTTGG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation