Incidental Mutation 'IGL03271:Sult3a1'
ID415252
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sult3a1
Ensembl Gene ENSMUSG00000069668
Gene Namesulfotransferase family 3A, member 1
SynonymsSultx2
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.223) question?
Stock #IGL03271
Quality Score
Status
Chromosome10
Chromosomal Location33857721-33879532 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 33864001 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 19 (T19A)
Ref Sequence ENSEMBL: ENSMUSP00000151228 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000092597] [ENSMUST00000218204]
Predicted Effect probably benign
Transcript: ENSMUST00000092597
AA Change: T19A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000090259
Gene: ENSMUSG00000069668
AA Change: T19A

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 36 283 1.8e-81 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000218204
AA Change: T19A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 51 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Actbl2 G T 13: 111,255,874 V248L probably benign Het
Actl6b T A 5: 137,565,984 I256N probably damaging Het
Agl G T 3: 116,779,127 T825K probably benign Het
Arid5b A T 10: 68,097,457 S629T possibly damaging Het
Atp13a2 T C 4: 141,000,397 I495T possibly damaging Het
Bcl6 G T 16: 23,970,006 H537Q probably benign Het
Cdh12 A G 15: 21,586,453 E786G probably benign Het
Cep290 T A 10: 100,537,801 N1307K probably benign Het
Cops3 A T 11: 59,833,063 N89K probably damaging Het
Cyp4a29 T C 4: 115,254,508 V494A probably damaging Het
Dlg1 A G 16: 31,857,892 H675R possibly damaging Het
Dnajc6 T A 4: 101,508,077 probably benign Het
Dock10 C A 1: 80,505,409 K2107N probably damaging Het
Dopey1 T A 9: 86,504,222 L382* probably null Het
Faxc A C 4: 21,948,757 K156N possibly damaging Het
Fut2 C T 7: 45,650,769 G193E possibly damaging Het
Gapvd1 C A 2: 34,727,207 probably benign Het
Gfm1 T C 3: 67,474,743 Y717H probably damaging Het
Gm4884 A T 7: 41,043,275 T223S probably benign Het
Gstm3 C A 3: 107,966,197 V153F possibly damaging Het
H2-M10.5 G T 17: 36,773,351 L68F possibly damaging Het
Hmcn1 G T 1: 150,598,424 H4756N possibly damaging Het
Ift140 C A 17: 25,087,906 R872S probably damaging Het
Lars2 T A 9: 123,459,484 probably null Het
Ltbp4 A G 7: 27,329,815 V149A unknown Het
Mpp2 A T 11: 102,063,423 probably benign Het
Mybbp1a A G 11: 72,443,918 probably benign Het
Nxpe4 C A 9: 48,393,045 P144Q probably damaging Het
Olfr1341 T A 4: 118,709,785 I126N probably damaging Het
Olfr478 C T 7: 108,031,507 V279M probably damaging Het
Parp4 C A 14: 56,585,625 N67K probably benign Het
Pdk1 G T 2: 71,880,030 probably benign Het
Phip A T 9: 82,884,824 probably benign Het
Pls1 A G 9: 95,776,830 S202P probably benign Het
Pmpcb A G 5: 21,738,876 Y36C probably benign Het
Pole T C 5: 110,318,319 S1296P probably benign Het
Ptpn13 T C 5: 103,462,148 S4P probably damaging Het
Scgb2b7 A T 7: 31,705,081 C65S probably damaging Het
Sec61a2 A T 2: 5,882,934 L79* probably null Het
Slc2a5 T C 4: 150,135,583 L152P probably damaging Het
Smu1 C T 4: 40,738,408 G442D probably benign Het
Spag16 T A 1: 69,853,352 N97K probably benign Het
Spag6l C T 16: 16,780,728 D300N probably damaging Het
Ttll6 A G 11: 96,156,687 H704R probably benign Het
Uba1 T A X: 20,675,717 D569E probably damaging Het
Umodl1 T A 17: 30,986,499 Y689* probably null Het
Unc80 A G 1: 66,695,603 probably benign Het
Utp15 C A 13: 98,253,694 V282F probably damaging Het
Vmn1r184 A G 7: 26,267,609 Y260C probably benign Het
Vmn1r69 A G 7: 10,580,669 V45A probably benign Het
Vmn2r4 C A 3: 64,398,429 R524L probably benign Het
Other mutations in Sult3a1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01984:Sult3a1 APN 10 33879209 nonsense probably null
IGL02269:Sult3a1 APN 10 33879263 missense probably benign 0.25
IGL02302:Sult3a1 APN 10 33866575 missense possibly damaging 0.81
IGL02947:Sult3a1 APN 10 33864050 missense possibly damaging 0.92
IGL02966:Sult3a1 APN 10 33877273 splice site probably benign
IGL03367:Sult3a1 APN 10 33877346 missense probably benign 0.01
R0539:Sult3a1 UTSW 10 33866523 missense probably damaging 1.00
R0627:Sult3a1 UTSW 10 33864014 missense probably benign 0.00
R0838:Sult3a1 UTSW 10 33879288 missense probably damaging 0.99
R1538:Sult3a1 UTSW 10 33870170 missense probably benign 0.29
R1604:Sult3a1 UTSW 10 33866620 missense probably damaging 1.00
R1622:Sult3a1 UTSW 10 33870250 missense probably benign 0.39
R3031:Sult3a1 UTSW 10 33877349 missense possibly damaging 0.70
R4933:Sult3a1 UTSW 10 33866554 missense probably damaging 1.00
R5943:Sult3a1 UTSW 10 33866641 missense probably damaging 0.99
R6440:Sult3a1 UTSW 10 33870202 missense possibly damaging 0.46
R7140:Sult3a1 UTSW 10 33877287 missense probably damaging 1.00
R7356:Sult3a1 UTSW 10 33866583 missense probably benign 0.25
R8342:Sult3a1 UTSW 10 33866521 missense probably damaging 1.00
Posted On2016-08-02