Incidental Mutation 'IGL03273:Gm11937'
ID415332
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm11937
Ensembl Gene ENSMUSG00000058725
Gene Namepredicted gene 11937
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL03273
Quality Score
Status
Chromosome11
Chromosomal Location99609794-99610189 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) C to T at 99609801 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000074461 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000074926] [ENSMUST00000076478]
Predicted Effect probably benign
Transcript: ENSMUST00000074926
SMART Domains Protein: ENSMUSP00000074461
Gene: ENSMUSG00000060756

DomainStartEndE-ValueType
Pfam:Keratin_B2_2 1 56 5.8e-4 PFAM
Pfam:Keratin_B2 1 72 2.6e-12 PFAM
Pfam:Keratin_B2_2 53 101 1.3e-5 PFAM
Pfam:Keratin_B2_2 92 131 6.1e-4 PFAM
Predicted Effect unknown
Transcript: ENSMUST00000076478
AA Change: C130Y
SMART Domains Protein: ENSMUSP00000075802
Gene: ENSMUSG00000058725
AA Change: C130Y

DomainStartEndE-ValueType
Pfam:Keratin_B2_2 1 56 5.8e-4 PFAM
Pfam:Keratin_B2 1 72 2.6e-12 PFAM
Pfam:Keratin_B2_2 53 101 1.3e-5 PFAM
Pfam:Keratin_B2_2 92 131 6.1e-4 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930524N10Rik A T X: 154,339,701 F114L probably benign Het
Aaas A G 15: 102,349,995 I29T probably damaging Het
Adam32 T A 8: 24,921,340 I102F probably damaging Het
Aldoart1 T C 4: 72,852,109 K154R probably benign Het
BC052040 A G 2: 115,631,991 Y68C probably damaging Het
Cep63 T C 9: 102,602,467 K349E probably benign Het
Col28a1 A G 6: 8,103,484 probably benign Het
Dennd4c A G 4: 86,777,796 N130S probably damaging Het
Dnah5 T G 15: 28,458,649 F4477L probably damaging Het
Fbln7 A T 2: 128,895,470 T402S probably benign Het
Frem2 A C 3: 53,537,509 Y2400* probably null Het
Guca1a T C 17: 47,395,173 D127G probably benign Het
Hrh3 T A 2: 180,100,648 T396S possibly damaging Het
Map1a A G 2: 121,300,238 N512D probably damaging Het
Mysm1 A C 4: 94,965,718 S215A probably damaging Het
Nelfcd G A 2: 174,426,832 A559T possibly damaging Het
Nup93 T A 8: 94,306,277 D556E probably benign Het
Ofcc1 T A 13: 40,180,525 K363N probably damaging Het
Psme4 T A 11: 30,848,130 S1374R probably damaging Het
Slitrk2 T C X: 66,653,996 I31T probably benign Het
Stk40 A G 4: 126,123,806 N42S possibly damaging Het
Tarbp1 A G 8: 126,453,835 L600P probably damaging Het
Tjp1 T C 7: 65,299,799 S1692G probably damaging Het
Tmem63c G T 12: 87,081,802 V534L probably damaging Het
Vmn2r77 A G 7: 86,811,286 K607E probably damaging Het
Zfp292 A T 4: 34,806,163 S2299T probably benign Het
Other mutations in Gm11937
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1355:Gm11937 UTSW 11 99609907 missense possibly damaging 0.94
R4401:Gm11937 UTSW 11 99610075 missense probably damaging 1.00
R6736:Gm11937 UTSW 11 99610074 missense probably damaging 0.97
Posted On2016-08-02