Incidental Mutation 'IGL03276:Slc30a9'
ID415430
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc30a9
Ensembl Gene ENSMUSG00000029221
Gene Namesolute carrier family 30 (zinc transporter), member 9
Synonyms2310024J23Rik, GAC63
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.916) question?
Stock #IGL03276
Quality Score
Status
Chromosome5
Chromosomal Location67306955-67358443 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 67349917 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000144067 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000113676] [ENSMUST00000162372] [ENSMUST00000202521]
Predicted Effect probably benign
Transcript: ENSMUST00000113676
SMART Domains Protein: ENSMUSP00000109306
Gene: ENSMUSG00000029221

DomainStartEndE-ValueType
low complexity region 17 32 N/A INTRINSIC
PDB:2ENK|A 103 196 2e-54 PDB
SCOP:d1d4ua1 106 174 3e-28 SMART
Pfam:Cation_efflux 219 547 1.6e-41 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000161169
Predicted Effect probably benign
Transcript: ENSMUST00000162372
SMART Domains Protein: ENSMUSP00000124047
Gene: ENSMUSG00000029221

DomainStartEndE-ValueType
low complexity region 17 32 N/A INTRINSIC
PDB:2ENK|A 123 216 2e-54 PDB
SCOP:d1d4ua1 126 194 5e-28 SMART
Pfam:Cation_efflux 239 449 1e-33 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000202521
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arhgef25 A C 10: 127,185,925 F202V possibly damaging Het
Atrnl1 A T 19: 57,652,927 N336Y probably damaging Het
Bicc1 T C 10: 70,953,438 D381G possibly damaging Het
Cabin1 A T 10: 75,732,413 L912Q probably damaging Het
Fam83e A G 7: 45,723,460 D165G possibly damaging Het
Foxn1 T A 11: 78,371,124 T140S probably benign Het
Ggt1 A G 10: 75,580,497 probably benign Het
Kctd8 A T 5: 69,340,586 M239K possibly damaging Het
Kdm4d A T 9: 14,464,542 C7S probably benign Het
Kdm5a T A 6: 120,402,708 probably benign Het
Klrb1b T C 6: 128,815,205 N191S probably benign Het
Krt35 C T 11: 100,093,127 S349N probably benign Het
Krt75 A T 15: 101,568,376 D359E probably damaging Het
Lipo5 T C 19: 33,467,842 D109G unknown Het
Lsm12 T G 11: 102,182,944 I58L probably benign Het
Mxd4 T C 5: 34,177,744 D99G probably benign Het
Nlrp4a T A 7: 26,464,190 N927K probably damaging Het
Olfm2 A G 9: 20,668,787 probably benign Het
Pkhd1l1 T C 15: 44,594,584 V4103A possibly damaging Het
Snap91 T C 9: 86,825,012 T242A possibly damaging Het
Srp19 A C 18: 34,331,790 T28P probably damaging Het
Tenm2 C T 11: 36,072,776 V943I possibly damaging Het
Tgfb3 T C 12: 86,057,868 E384G probably damaging Het
Tmem39a T A 16: 38,585,284 N74K probably benign Het
Tnfrsf11a A G 1: 105,821,490 Y211C probably damaging Het
Other mutations in Slc30a9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00792:Slc30a9 APN 5 67342109 missense probably damaging 1.00
IGL00975:Slc30a9 APN 5 67349826 missense probably damaging 1.00
IGL01129:Slc30a9 APN 5 67342143 missense probably damaging 1.00
IGL01377:Slc30a9 APN 5 67315830 missense probably benign
IGL01785:Slc30a9 APN 5 67346238 splice site probably benign
IGL01786:Slc30a9 APN 5 67346238 splice site probably benign
IGL02407:Slc30a9 APN 5 67352722 missense probably damaging 1.00
IGL03185:Slc30a9 APN 5 67333063 missense probably benign
IGL03380:Slc30a9 APN 5 67315711 missense probably benign 0.04
ANU74:Slc30a9 UTSW 5 67349852 missense probably damaging 1.00
R0539:Slc30a9 UTSW 5 67334610 missense probably damaging 1.00
R1401:Slc30a9 UTSW 5 67352662 missense probably benign
R1554:Slc30a9 UTSW 5 67326921 missense probably damaging 1.00
R1824:Slc30a9 UTSW 5 67348052 missense probably damaging 1.00
R2029:Slc30a9 UTSW 5 67339975 nonsense probably null
R4385:Slc30a9 UTSW 5 67315767 missense probably damaging 1.00
R4704:Slc30a9 UTSW 5 67342273 intron probably benign
R4868:Slc30a9 UTSW 5 67324683 missense probably benign
R4907:Slc30a9 UTSW 5 67346162 missense probably damaging 1.00
R5553:Slc30a9 UTSW 5 67345604 intron probably null
R6002:Slc30a9 UTSW 5 67342117 missense probably damaging 1.00
R6477:Slc30a9 UTSW 5 67328524 missense probably benign 0.01
R6718:Slc30a9 UTSW 5 67333100 missense probably damaging 1.00
R7113:Slc30a9 UTSW 5 67326862 missense probably benign 0.17
R7224:Slc30a9 UTSW 5 67315701 missense probably benign
R7327:Slc30a9 UTSW 5 67342119 missense probably damaging 1.00
R7394:Slc30a9 UTSW 5 67352766 critical splice donor site probably null
R7467:Slc30a9 UTSW 5 67345644 missense probably benign 0.08
R7514:Slc30a9 UTSW 5 67348078 missense possibly damaging 0.68
R8020:Slc30a9 UTSW 5 67307033 start gained probably benign
Z1176:Slc30a9 UTSW 5 67339958 missense probably damaging 1.00
Posted On2016-08-02