Incidental Mutation 'IGL03282:Gm10073'
ID415631
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm10073
Ensembl Gene ENSMUSG00000060019
Gene Namepredicted pseudogene 10073
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL03282
Quality Score
Status
Chromosome8
Chromosomal Location106572966-106573461 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 106573340 bp
ZygosityHeterozygous
Amino Acid Change Valine to Aspartic acid at position 4 (V4D)
Ref Sequence ENSEMBL: ENSMUSP00000129695 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000073722]
Predicted Effect probably benign
Transcript: ENSMUST00000073722
AA Change: V4D

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
SMART Domains Protein: ENSMUSP00000129695
Gene: ENSMUSG00000060019
AA Change: V4D

DomainStartEndE-ValueType
Pfam:Ribosomal_60s 22 113 4.2e-29 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atl1 A G 12: 69,954,464 I333M possibly damaging Het
Atxn2 A G 5: 121,785,235 T52A probably benign Het
Atxn7 T A 14: 14,100,564 L750H probably damaging Het
Cadps T C 14: 12,465,856 probably benign Het
Cts6 T A 13: 61,196,447 I264F possibly damaging Het
Dnah6 G T 6: 73,053,647 probably benign Het
Epg5 A G 18: 77,986,426 S1335G probably benign Het
Gpld1 T A 13: 24,971,408 M342K probably benign Het
Herc1 T A 9: 66,451,459 F2607L probably benign Het
Ighv2-9-1 T C 12: 113,769,865 Y112C probably damaging Het
Itga4 A T 2: 79,325,594 H968L probably damaging Het
Me1 C T 9: 86,613,596 R286Q probably damaging Het
Med1 G A 11: 98,156,817 T1051M probably damaging Het
Msh2 T G 17: 87,689,002 D379E probably benign Het
Mup4 T A 4: 59,958,547 M118L possibly damaging Het
Ostm1 A T 10: 42,698,231 S152C probably damaging Het
Pla2g1b A G 5: 115,470,880 N45D probably damaging Het
Rab21 A G 10: 115,298,898 probably benign Het
Rapgef4 G A 2: 72,205,752 probably benign Het
Slc38a8 G T 8: 119,499,716 N111K probably damaging Het
Snrnp35 A G 5: 124,490,309 T62A probably damaging Het
Strn3 T C 12: 51,627,209 I540V probably benign Het
Tgm1 A G 14: 55,711,070 V208A probably damaging Het
Vmn1r62 A T 7: 5,675,548 D76V possibly damaging Het
Vmn1r90 T A 7: 14,561,501 H224L probably benign Het
Vmn1r90 A T 7: 14,562,168 S2T possibly damaging Het
Other mutations in Gm10073
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01520:Gm10073 APN 8 106573269 missense probably benign 0.13
IGL02433:Gm10073 APN 8 106573319 missense probably benign 0.05
R1664:Gm10073 UTSW 8 106573232 missense probably damaging 1.00
Posted On2016-08-02