Incidental Mutation 'IGL03284:Gm7257'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm7257
Ensembl Gene ENSMUSG00000023093
Gene Namepredicted gene 7257
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.074) question?
Stock #IGL03284
Quality Score
Chromosomal Location36431884-36434938 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 36433463 bp
Amino Acid Change Cysteine to Serine at position 96 (C96S)
Ref Sequence ENSEMBL: ENSMUSP00000048154 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000041537]
Predicted Effect probably damaging
Transcript: ENSMUST00000041537
AA Change: C96S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000048154
Gene: ENSMUSG00000023093
AA Change: C96S

signal peptide 1 21 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810013L24Rik A G 16: 8,855,922 I238V possibly damaging Het
Adam5 A T 8: 24,786,338 probably benign Het
Atxn7l3b T C 10: 112,928,526 D66G probably benign Het
Dmac2 T C 7: 25,622,426 probably null Het
Ephb2 A G 4: 136,661,516 M590T probably damaging Het
Fbxo41 C T 6: 85,479,765 R474H probably damaging Het
Fcgbp G T 7: 28,085,432 A306S possibly damaging Het
Hmg20a A G 9: 56,481,617 D156G probably benign Het
Mast4 A G 13: 102,751,397 V1168A probably damaging Het
Oog2 A G 4: 144,196,607 probably benign Het
Pkhd1l1 T A 15: 44,547,518 probably benign Het
Psmd6 A T 14: 14,112,546 N351K probably benign Het
Ralgps1 T C 2: 33,146,565 probably benign Het
Rbl1 C T 2: 157,194,069 probably benign Het
Smarcc1 G A 9: 110,175,074 V399I probably benign Het
Srek1 C A 13: 103,760,537 V99F probably damaging Het
Styxl1 A G 5: 135,757,095 V32A possibly damaging Het
Tnn C T 1: 160,125,452 V673I probably benign Het
Vmn2r107 T A 17: 20,356,911 D390E probably benign Het
Other mutations in Gm7257
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00329:Gm7257 APN 9 36432902 splice site probably benign
IGL01799:Gm7257 APN 9 36432883 missense possibly damaging 0.59
IGL03018:Gm7257 APN 9 36433427 missense possibly damaging 0.89
IGL03178:Gm7257 APN 9 36432836 missense probably benign
R1157:Gm7257 UTSW 9 36432847 missense probably benign 0.01
R2032:Gm7257 UTSW 9 36432899 critical splice donor site probably null
R4879:Gm7257 UTSW 9 36432793 missense probably damaging 1.00
R4954:Gm7257 UTSW 9 36432860 missense probably benign 0.28
R5019:Gm7257 UTSW 9 36431902 missense probably benign 0.05
Posted On2016-08-02