Incidental Mutation 'IGL03284:Gm7257'
ID415655
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm7257
Ensembl Gene ENSMUSG00000023093
Gene Namepredicted gene 7257
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.074) question?
Stock #IGL03284
Quality Score
Status
Chromosome9
Chromosomal Location36431884-36434938 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 36433463 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Serine at position 96 (C96S)
Ref Sequence ENSEMBL: ENSMUSP00000048154 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000041537]
Predicted Effect probably damaging
Transcript: ENSMUST00000041537
AA Change: C96S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000048154
Gene: ENSMUSG00000023093
AA Change: C96S

DomainStartEndE-ValueType
signal peptide 1 21 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810013L24Rik A G 16: 8,855,922 I238V possibly damaging Het
Adam5 A T 8: 24,786,338 probably benign Het
Atxn7l3b T C 10: 112,928,526 D66G probably benign Het
Dmac2 T C 7: 25,622,426 probably null Het
Ephb2 A G 4: 136,661,516 M590T probably damaging Het
Fbxo41 C T 6: 85,479,765 R474H probably damaging Het
Fcgbp G T 7: 28,085,432 A306S possibly damaging Het
Hmg20a A G 9: 56,481,617 D156G probably benign Het
Mast4 A G 13: 102,751,397 V1168A probably damaging Het
Oog2 A G 4: 144,196,607 probably benign Het
Pkhd1l1 T A 15: 44,547,518 probably benign Het
Psmd6 A T 14: 14,112,546 N351K probably benign Het
Ralgps1 T C 2: 33,146,565 probably benign Het
Rbl1 C T 2: 157,194,069 probably benign Het
Smarcc1 G A 9: 110,175,074 V399I probably benign Het
Srek1 C A 13: 103,760,537 V99F probably damaging Het
Styxl1 A G 5: 135,757,095 V32A possibly damaging Het
Tnn C T 1: 160,125,452 V673I probably benign Het
Vmn2r107 T A 17: 20,356,911 D390E probably benign Het
Other mutations in Gm7257
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00329:Gm7257 APN 9 36432902 splice site probably benign
IGL01799:Gm7257 APN 9 36432883 missense possibly damaging 0.59
IGL03018:Gm7257 APN 9 36433427 missense possibly damaging 0.89
IGL03178:Gm7257 APN 9 36432836 missense probably benign
R1157:Gm7257 UTSW 9 36432847 missense probably benign 0.01
R2032:Gm7257 UTSW 9 36432899 critical splice donor site probably null
R4879:Gm7257 UTSW 9 36432793 missense probably damaging 1.00
R4954:Gm7257 UTSW 9 36432860 missense probably benign 0.28
R5019:Gm7257 UTSW 9 36431902 missense probably benign 0.05
Posted On2016-08-02