Incidental Mutation 'IGL03287:Krt87'
ID415771
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Krt87
Ensembl Gene ENSMUSG00000047641
Gene Namekeratin 87
SynonymsKrt83, Krt2-25
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.103) question?
Stock #IGL03287
Quality Score
Status
Chromosome15
Chromosomal Location101431038-101438804 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 101432337 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000080613 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000068904] [ENSMUST00000081945]
Predicted Effect probably benign
Transcript: ENSMUST00000068904
SMART Domains Protein: ENSMUSP00000069900
Gene: ENSMUSG00000023039

DomainStartEndE-ValueType
low complexity region 27 42 N/A INTRINSIC
Pfam:Keratin_2_head 43 81 3.2e-12 PFAM
Filament 84 396 1.95e-174 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000081945
SMART Domains Protein: ENSMUSP00000080613
Gene: ENSMUSG00000047641

DomainStartEndE-ValueType
Pfam:Keratin_2_head 3 107 1e-12 PFAM
Filament 110 421 6.45e-148 SMART
low complexity region 425 440 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000131069
Predicted Effect noncoding transcript
Transcript: ENSMUST00000183401
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 21 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930519G04Rik A T 5: 114,870,176 D17V probably damaging Het
Cdh5 T A 8: 104,128,115 V225E probably damaging Het
Cfap52 C T 11: 67,935,976 probably benign Het
Cib4 A G 5: 30,488,543 L127P probably benign Het
Fbln2 A G 6: 91,233,494 H140R probably damaging Het
Grm8 A G 6: 27,760,255 F359L possibly damaging Het
Kat7 A T 11: 95,300,109 D150E probably damaging Het
Kif1b A G 4: 149,214,981 I944T possibly damaging Het
Mast1 T C 8: 84,913,353 S1142G probably benign Het
Neb A G 2: 52,137,323 Y6889H probably damaging Het
Olfr1 A T 11: 73,396,019 M1K probably null Het
Olfr1337 A G 4: 118,782,354 V77A possibly damaging Het
Plk4 A T 3: 40,805,118 I150L probably benign Het
Scn5a T C 9: 119,489,778 D1598G probably damaging Het
Skor2 A G 18: 76,876,135 K925E probably damaging Het
Slc25a29 A T 12: 108,831,209 F22L possibly damaging Het
Slc27a2 A G 2: 126,553,392 T80A probably damaging Het
Tlr3 A G 8: 45,402,780 V121A probably benign Het
Tubgcp3 A T 8: 12,639,630 D545E possibly damaging Het
Zdhhc8 T C 16: 18,225,100 Y412C probably benign Het
Zmynd12 A G 4: 119,453,579 E328G probably damaging Het
Other mutations in Krt87
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00987:Krt87 APN 15 101438446 missense probably benign 0.00
IGL01019:Krt87 APN 15 101438431 missense possibly damaging 0.84
IGL01066:Krt87 APN 15 101438385 critical splice donor site probably null
IGL01087:Krt87 APN 15 101431825 missense probably benign 0.27
IGL01572:Krt87 APN 15 101436533 missense probably benign 0.33
IGL02716:Krt87 APN 15 101434604 missense possibly damaging 0.52
R0144:Krt87 UTSW 15 101438661 missense probably benign 0.04
R2196:Krt87 UTSW 15 101438433 missense probably damaging 0.99
R2209:Krt87 UTSW 15 101433108 missense probably benign 0.42
R5651:Krt87 UTSW 15 101434029 missense possibly damaging 0.94
R6437:Krt87 UTSW 15 101438392 missense possibly damaging 0.95
R6615:Krt87 UTSW 15 101436562 missense probably benign 0.02
R6680:Krt87 UTSW 15 101433978 missense probably damaging 1.00
R7541:Krt87 UTSW 15 101438634 missense probably damaging 1.00
R7617:Krt87 UTSW 15 101438545 missense probably benign 0.38
Posted On2016-08-02