Incidental Mutation 'IGL03297:Sprr4'
ID416128
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sprr4
Ensembl Gene ENSMUSG00000045566
Gene Namesmall proline-rich protein 4
Synonyms
Accession Numbers

Genbank: NM_173070; MGI: 2654508

Is this an essential gene? Possibly non essential (E-score: 0.480) question?
Stock #IGL03297
Quality Score
Status
Chromosome3
Chromosomal Location92500263-92500493 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 92500424 bp
ZygosityHeterozygous
Amino Acid Change Proline to Serine at position 24 (P24S)
Ref Sequence ENSEMBL: ENSMUSP00000051559 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000062129]
Predicted Effect unknown
Transcript: ENSMUST00000062129
AA Change: P24S
SMART Domains Protein: ENSMUSP00000051559
Gene: ENSMUSG00000045566
AA Change: P24S

DomainStartEndE-ValueType
low complexity region 5 33 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adamtsl1 G A 4: 86,423,426 G1624S probably damaging Het
Adhfe1 A G 1: 9,549,948 probably benign Het
Ano6 C A 15: 95,962,277 T760N probably damaging Het
Camsap2 T C 1: 136,297,801 M196V probably benign Het
Cd209d T C 8: 3,878,476 D3G possibly damaging Het
Cdh5 T A 8: 104,128,199 F253Y probably damaging Het
Cnot10 T C 9: 114,598,716 E610G possibly damaging Het
Cnot4 T C 6: 35,024,223 N579S probably benign Het
Csmd1 G T 8: 16,009,432 S2101* probably null Het
Dgkq C A 5: 108,650,274 R706L probably damaging Het
Gm5422 T C 10: 31,249,731 noncoding transcript Het
Gpr34 A G X: 13,639,442 Y70C probably damaging Het
Herc6 T A 6: 57,662,389 L914Q probably benign Het
Ifitm6 T C 7: 141,016,035 Y115C probably damaging Het
Iqcg G T 16: 33,035,632 probably benign Het
Myo15 A G 11: 60,479,141 D909G probably damaging Het
Nefl A G 14: 68,084,224 T88A possibly damaging Het
Nfatc2 T A 2: 168,536,218 N509I probably damaging Het
Nkd1 T C 8: 88,574,274 probably benign Het
Npas2 T C 1: 39,292,690 V62A possibly damaging Het
Oas2 T G 5: 120,735,085 D635A possibly damaging Het
Obscn C T 11: 59,060,886 V4014M possibly damaging Het
Ogfr C A 2: 180,594,407 H262N possibly damaging Het
Olfr433 T G 1: 174,042,117 S56A probably benign Het
Olfr913 A T 9: 38,594,525 L101F probably benign Het
Pa2g4 T C 10: 128,563,236 D104G probably damaging Het
Parp11 T C 6: 127,490,082 probably benign Het
Ppp2r5a C T 1: 191,354,762 V360I probably benign Het
Ptpn13 A T 5: 103,541,077 K912I probably benign Het
Sec16a A G 2: 26,439,190 S938P probably benign Het
Slc15a1 A C 14: 121,486,684 I170S probably damaging Het
Smchd1 T C 17: 71,349,700 N1924S probably benign Het
Trim30b A T 7: 104,365,895 N95K probably benign Het
Tyw1 C T 5: 130,340,734 A687V probably damaging Het
Vmn2r14 T A 5: 109,216,107 I648F probably damaging Het
Vmn2r78 T A 7: 86,920,761 C162* probably null Het
Other mutations in Sprr4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01420:Sprr4 APN 3 92500384 missense unknown
N/A - 293:Sprr4 UTSW 3 92500343 nonsense probably null
R4765:Sprr4 UTSW 3 92500409 missense unknown
R6250:Sprr4 UTSW 3 92500463 missense unknown
Posted On2016-08-02